References: P through S

References P-S used for Sacred Cacti 4th edition.

This references list is still in progress and will continue to be modified during the editing process. If anything new has not been added yet and you need to know it now; drop me an email.

[Brackets around a title indicates it is an English translation of the actual title. ]

Incomplete citations or the use of the qualifier “From” usually indicates that the paper listed was a second-hand reference. This means that this work was unavailable to us and was the reference that was cited by our information source.

As a single listing

A through D

E through J

K through O

T through Z

 

 

 

Pálenícek T et al. (2008) Psychopharmacology (Berl). 196 (1): 51–62. “Mescaline effects on rat behavior and its time profile in serum and brain tissue after a single subcutaneous dose.” (T. Pálenícek, M. Balíková, V. Bubeníková-Valesová & J. Horácek)

Palmieri, V.M. (1942) Rassegna Clinica Scientifica, 20. “La mescalina e l’ebbrezza peyotilica nell’uomo.”

Palmieri, V.M. & G. Lacroix (1941) Atti Congresso de medicina legale, 8 (1940): 540–549. “Ulteriori ricerche sull’intossicazione da mescalina.”

Palomino Yamamoto, Manuel (1972) Doctoral Thesis. Universidad Nacional Mayor de San Marcos (UNMSM), Lima. “Farmacoquimica de Cactaceae(sic) peruana.” This noncirculating work exists as a single copy in the Library of the Instituto Nacional de Salud, Av. Salaverry, Lima. The whole thesis is devoted to the biochemical study of Trichocereus santaensis Rauh et Backeberg. Photocopying is not permitted so Dr. Carlos Ostolaza graciously read it on my behalf and provided information on its contents.]

Pang, Hildegard [Hilda] Delgado (1992) Pre-Columbian Art. Investigations and Insights. University of Oklahoma Press. 330 pages. ISBN-10: 0806123796; ISBN-13: 978-0806123790. (first edition)

Panico, A.M. et al. (2007) Journal of Ethnopharmacology, 111 (2): 315–321. “Effect of hyaluronic acid and polysaccharides from Opuntia ficus indica (L.) cladodes on the metabolism of human chondrocyte cultures.” (A.M. Panico, V. Cardile, F. Garufi, C. Puglia, F. Bonina & S. Ronsisvalle)

Pap, Z. (1936)b Zeitschrift für die gesamte Neurologie und Psychiatrie, 155: 655–664. “Einwirkung des Meskalinrausches auf die post-hypnotischen Sinnestäuschungen.” [See also (1936)a Orvosi hetilap, 80: 75–78.]

Pardanani, J.H. et al. (1977) Lloydia, 40 (6): 585–590 “Cactus Alkaloids. XXXVI. Mescaline and related compounds from Trichocereus peruvianus.” (J.H. Pardanani, J.L. McLaughlin, R.W. Kondrat & R.G. Cooks.)

Pardanani, J.H. et al. (1978) Lloydia, 41 (3): 286–288 “Cactus Alkaloids. XXXVII. Mescaline and Related Compounds from Opuntia spinosior.” (J.H. Pardanani, B.N. Meyer, J.L. McLaughlin, W.H. Earle & R.G. Engard )

Parikh, V.M. & J.K.N. Jones (1966) Canadian Journal of Chemistry, 44: 327–333. “Cholla Gum. I. Structure of the Degraded Cholla Gum.”

Paris, René (1951) Comptes Rendus Hebdomaires des Séances de L’Académie des Sciences, 233: 90–92. “Sur un flavonoside des fleurs d’Opuntia vulgaris Miller.”

Paris, René & Hélène Moyse-Mignon (1949) Comptes Rendus Hebdomaires des Séances de L’Académie des Sciences, 229: 86–88. “Étude chimique et pharmacodynamique préliminaire d’une Loganiacée du Gabon: Mostuea stimulans A.Chev.”

Park, E.-H. et al. (2001) Fitoterapia,72: 288–290. “An anti-inflammatory principle from cactus.”

Park, E.-H. et al. (1998) Archives of Pharmacal Research, 21 (1998) 30–34. “Studies on the pharmacological actions of cactus: identification of its anti-inflammatory effect.” (E.-H. Park, J.H. Kahng & E.-A. Paek)

Parmentier (1838) L’Horticulteur Belge, 5: 66 [Cereus terscheckii] [From Britton & Rose] See also Pfeiffer 1837

Pascarosa, Paul & Futterman, Sanford (1976) Journal of Psychedelic Drugs, 8 (3): 215–221. “Ethnopsychedelic Therapy for Alcoholics: Observations in the Peyote Ritual of the Native American Church.”

Passie, Torsen (1994) Jahrbuch des Europäischen Collegiums für Bewußtseinsstudien, 1993/1994: 103–111. “Ausrichtungen, Methoden und Ergebnisse früher Meskalinforschungen im deutschsprachigen Raum (bis 1950)”

Patel, A.R. (1968) Fortschritte der Arzneimittelforschung (i.e. Progress in Drug Research), 11: 11–47. (E. Jucker, ed.) “Mescaline and Related Compounds.” [Birkhäuser Verlag, Basel und Stuttgart.]

Patterson, Alex (1992) Rock Art Symbols of the Greater Southwest. Johnson Books: Boulder, Colorado.

Patton, Mark (1990) Current Anthropology 31 (5): 554–558 “On Entoptic Images in Context: Art, Monuments and Society in Neolithic Brittany.”

Patton, Mark (1993) Statements in Stone. Routledge: London.

Patzig, B. & W. Block (1953) Naturwissenschaften, 40: 13–17. “Zur Auffassung des schizophrenen Prozessgeschehens nach Tierversuchen mit 14C-radioaktivem Meskalin.”

Paul, A.G. (1973) Lloydia, 36 (1): 36–45. “Biosynthesis of the peyote alkaloids.”

Paul, A.G. et al. (1969)a The Chemical Society, London. Chemical Communications, [Journal of the Chemical Society, D.] 14: 838. “Biosynthesis of Peyote Alkaloids.” (A.G. Paul, K.L. Khanna, H. Rosenberg & M. Takido)

Paul, A.G. et al. (1969)b Lloydia, 32 (1): 36–39. “The Roles of 3,4,5-Trihydroxyphenethylamine and 3,4-Dimethoxyphenethylamine in the Biosynthesis of Mescaline.” (A.G. Paul, H. Rosenberg & K.L. Khanna)

Paulson, James C. & William O. McClure (1973) Molecular Pharmacology, 9 (1): 41–50. “Inhibition of Axoplasmic Transport by Mescaline and Other Trimethoxyphenylalkylamines.” [Mescaline is a reversible inhibitor of axoplasmic transport.]

Pawar, R.S. et al. (2014) Journal of Pharmaceutical and Biomedical Analysis, 88: 457–466. “Determination of selected biogenic amines in Acacia rigidula plant materials and dietary supplements using LC–MS/MS methods.” (Rahul S. Pawar, Erich Grundel, Ali Reza Fardin-Kia & Jeanne I. Rader)

Payne (1961) Industrial Chemist, 37: 523.

Pearl, Irwin S. (1948) Journal of the American Chemical Society, 70 (5): 1746–1748. “Synthesis of Syringaldehyde.”

Pechánek, J. (1969) Kaktusy, 69: 76–81 & 109–113. “Lophophora Coult.” [L. lewinii Rusby & L. jourdaniana Krzgr] [Habermann 1975 gives as “69, 4, ; 76 and 69, 5, p. 103–113.”]

Pechánek, J. (1983) Kaktusy,19: 50–53. “Lophophora Williamsii var. decipiens Croizat.”

Pekkarinen, A. & M.-E. Pitkanen (1955) Scand. J. Clin. Lab. Inves. 7: 1 [from Usdin & Efron 1979]

Pellerin, J. et al. (1958) Revue Canadienne de Biologie,  17 (3): 267–298. “Biogenesis and Metabolism of Catecholamines.” (J. Pellerin, J. Leduc and A. D’Iorio)

Pemberton, I.J. et al. (1993) Journal of Animal Sciences, 71:467–470. “Technical note: an improved method for extraction and quantification of toxic phenethylamines from Acacia berlandieri.” (I.J. Pemberton, G.R. Smith, T.D.A Forbes & C.M. Hensarling)

Pennes, Harry H. (1954) Journal of Nervous and Mental Disease, 119 (2): 95–112. “Clinical reactions of schizophrenics to Sodium Amytal, Pervitin Hydrochloride, Mescaline Sulfate, and D-Lysergic Acid Diethylamide (LSD-25).”

Pennington, Campbell W. (1963) The Tarahumar of Mexico. Univ. Utah Press (Reprinted 1974: ISBN-10 0874800935; ISBN-13 9780874800937) 267 pages. (Also reprinted in 1996 by Editorial Agata, Guadalajara, Jalisco, Mexico, with 33 b/w & 12 full-colour photographs (found only in this edition) & 4 fold out maps in a back pocket)

Penington, N.J. & R.J. Reiffenstein (1986) European Journal of Pharmacology, 122 (3): 373–377. “Direct comparison of hallucinogenic phenethylamines and D-amphetamine on dorsal raphe neurons.”

Pepper, J.M. & J.A. MacDonald (1953) Canadian Journal of Chemistry, 31: 476–483. “The Synthesis of Syringaldehyde from Vanillin.”

Pereira, N.A. & D.S. de Oliveira (1961) Rev. Brasil Farm., 42: 13 [CA (1962) 56: 6486] [From Deulofeu & Ruveda 1971]

Perfumi, M. & R. Tacconi (1996) International Journal of Pharmacognosy, 34: 41–47. “Antihyperglycemic Effect of Fresh Opuntia dillenii Fruit from Tenerife (Canary Islands).”

Perry et al. (1965) “Studies of amines in normal and schizophrenic subjects.”from Amines Schizophrenia, Pap. Symp, Atlantic City. 1965: 31 [CA 68: 37621] (from Crosby & McLaughlin 1973)

Perry, S.Y. et al. (1991) Molecular Biotherapy, 3: 79–87. “Decreased mortality of normal murine sarcoma in mice treated with the immunomodulator, Acemannan.”

Petershofer-Halbmeyer, H. et al. (1982) Scientia pharmaceutica, 50: 29–34. “Isolierung von Hordenin (“Cactin”) aus Selenicereus grandiflorus (L.) Britt. & Rose und Selenicereus pteranthus (Link & Otto) Britt. & Rose” (H. Petershofer-Halbmayer, O. Kubelka, J. Jurenitsch & W. Kubelka)

Petrullo, Vincenzo (1934) The Diabolic Root. A Study of Peyotism, the New Indian Religion Among the Delaware. University of Pennsylvania Press, The University Museum. [Still a good book today.]

Peyote Foundation 1998 Press release re: 11,200 living peyote plants. Peyote Foundation: POBox 778, Kearny, AZ 85237.

Pfeiffer, Louis Georg(e) Karl (1837) Alg. Gartenz. 5: 370 [Cereus terscheckii Parmentier] [From Britton & Rose]

Piattelli, Maurio (1981) “The Betalains: Structure, Biosynthesis, and Chemical Taxonomy.” pp. 557–575, in: E.E. Conn (editor) The Biochemistry of Plants: A Comprehensive Treatise. Volume 7: Secondary Plant Products. Academic Press. ISBN 0-12-67507-1.

Piattelli, Maurio & F. Imperato (1969) Phytochemistry, 8: 1503–1507. “Betacyanins of the Family Cactaceae.”

Piattelli, Maurio & Luigi Minale (1964)a Phytochemistry, 3: 307–311. “Pigments of Centrospermae – II. Distribution of Betacyanins.”

Piattelli, Maurio & Luigi Minale (1964)b Phytochemistry, 3: 547–557. “Pigments of Centrospermae – I. Betacyanins from Phyllocactus Hybridus Hort. and Opuntia ficus-indica Mill.”

Piccinelli, D. (1955) Boll. Soc. Eustachiana e Ist. Sci. Univ. Camerino, 48: 105. [CA 53: 8372a] [From Smith 1977]

Piattelli, M. et al. (1964)a Rend. Accad. Sci. Fis. Mat. (Soc. Naz. Sci., Napoli), 31: 39–41. “Isolation and Structure of Indicaxanthine, a β-Xanthine from Opuntia ficus-indica.” (Mario Piattelli, Luigi Minale & Giuseppe Prota) [From 1966 CA 64: 5037a]

Piattelli, M. et al. (1964)b Tetrahedron, 20: 2325–2329. “Isolation, Structure and Absolute Configuration of Indicaxanthin.” (Mario Piattelli, Luigi Minale & Giuseppe Prota)

Piattelli, M. et al. (1965) Phytochemistry, 4: 121–125. “Pigments of Centrospermae – II. Betaxanthins from Beta vulgaris L..” (Mario Piattelli, Luigi Minale & Giuseppe Prota) [Mentions isolation from Opuntia ficus-indica]

Pictet et al. 1911 Ber 44: 2036

Pinkley, Homer V. (1969) Lloydia, 32 (3): 305–314. “Plant Admixtures to Ayahuasca, the South American Hallucinogenic Drink.” [Epiphyllum]

Pinkson, Tom Soloway (1995) Flowers of Wiricuta: A Gringo’s Journey To Shamanic Power. Wakan Press 0-9647542-0-7. 302 pages.

Pinschmidt, N.W. et al. (1945) Journal of Pharmacology and Experimental Therapeutics, 83: 45 -52. “Studies on the Antagonism of Sodium Succinate to Barbiturate Depression.” (N.W. Pinschimdt, Helen Ramsey & H.B. Haag)

Pittier, H. (1926) Manual de las Plantas Usuales de Venezuela. Litografia del Comercio, Caracas.

Pizzetti, Mariella (1985) Simon and Schuster’s Guide to Cacti and Succulents. ISBN: 0-671-55846-3/ 0-671-60231–4 (paperback) [Originally published in Italian as “Piante grasse” by Arnoldo Mondadori Editore S.p.A. Milan, 1985.]

Platonova, T.F. et al. (1958) Journal of General Chemistry of the USSR, 28: 3159- 3161. “Alkaloïds of Chenopodiaceæ: Arthrophytum leptocladum Popov.”

Plotkin, Mark (1994) Tales of a Shaman’s Apprentice. Penguin. ISBN 0-14-012991-X.

Plotnikoff, N.P. & H. Washington (1958) Proceedings of the Society for Experimental Biology and Medicine, 98 (3): 660–662. “Bioassay of Ataraxics Against Lethal Action of Mescaline in Mice.”

Pohorecky, L.A. et al. (1969) Journal of Pharmacology & Experimental Therapeutics, 165 (2): 190–195. “Enzymatic conversion of norepinephrine to epinephrine by the brain.” (L.A. Pohorecky, M. Zigmond, H. Karten & R.J. Wurtman)

Poisson, Jacques (1960) Annales Pharmaceutiques Françaises, 18: 764–765. “Présence de mescaline dans une Cactacée péruvienne.”

Poisson, Jacques (1961) Chemical Abstracts 55: 8448 [Abstracts Poisson 1960]

Polache, Ana & Luis Granero (2013) Frontiers in Behavioral Neuroscience, 7: 74. “Salsolinol and ethanol-derived excitation of dopamine mesolimbic neurons: new insights.”

Polia, Mario (1990) Quaderni di Avallon 23: 59–69. “Alcune riflessioni sull’uso delle droghe rituali nello sciamenesimo amerindio.”

Polia, Mario (1993) Altrove 1: 77–92. “L’uso del cactus mescalinico Trichocereus pachanoi nella medicina tradizionale andina.”

Polia, Mario (1997) Il Sangue Del Condor; Sciamani Delle Ande. Xenia Edizioni, Milano; 281 pages. ISBN 88-7273–203–4.

Pollard, J.C. et al. (1960) Comprehensive Psychiatry,  1: 377–380, “Controlled sensory input: a note on the technique of drug evaluation with a preliminary report on a comparative study of Sernyl, psilocybin and LSD.” (J.C. Pollard, C. Bakker, L. Uhr & D.F. Feurfile)

Poloni, A. (1956) Cervello 32: 400.

Polono, A. & G. Maffezzoni (1952) Sistema nervoso, 4: 578–581. “Le variazione dell’ attività colinergica del tessuto cerebrale per effetto della bulbocapnina, della mescalina e della dietilamide dell’ acido lisergico.”

Popelak, A. & G. Lettenbauer (1967) “The mesembrine alkaloids.” pp. 467–482 in Manske & Holmes (eds.) The Alkaloids. Vol. 9.

Popelak, A. et al. (1960)a Naturwissenschaften, 47: 156. “Zur Konstitution des Mesembrins.” (A. Popelak, E. Haack, G. Lettenbauer & H. Spingler) [From DeSmet 1996]

Popelak, A. et al. (1960)b Naturwissenschaften, 47: 231–232. “Die Strukture des Mesembrins und Mesembrenins.” (A. Popelak, G. Lettenbauer, E. Haack & H. Spingler) [From DeSmet 1996]

Popelak, A. et al. (1960)c Naturwissenschaften, 47: 241

Pophof, B. et al. (2005) Chemical Senses, 30 (1): 51–68. “Volatile organic compounds as signals in a plant-herbivore system: electrophysiological responses in olfactory sensilla of the moth Cactoblastis cactorum.”

Popoff, E.I. (1897) Vrach (St. Petersburg) 28: 1361. “K farmakologii pellotina.”

Porsch, Otto (1938) Cactaceae. Jahrbücher der Deutschen Kakteen-Gesellschaft. Entire May issue. “Das Bestäubungsleben der Kakteenblüte I.”

Post, R.M. et al. (1980) p. 685, in: Wood, J.M. (ed.) Neurobiology of Cerebralspinal Fluid. Vol. One., Plenum Press, New York.

Powell, A Michael & James F. Weedin (2004) Cacti of the Trans-Pecos & Adjacent Areas. Texas Tech University Press. ISBN 0-89672-531-6, 510 pages + 313 plates. This is quite possibly the best book that has ever been written about cacti.

Powell, C.E. & K.K. Chen (1956) Journal of the American Pharmaceutical Association, Scientific Edition, 45 (8): 559–561. “Pilocereine, a Cactus Alkaloid.”

Prajer, Z. (1968)a Informator Polskiego Towartzstwa Miƚosników Kaktusów, pp. 22–29, 111–129. “Peyotl-Bog-Diabeƚ-czy tylko zwykƚy kaktus?”

Prajer, Z. (1968)b Informator Polskiego Towartzstwa Miƚosników Kaktusów, pp. 120–129. “Peyotl-przez ‘mędrca skieƚko’.”

Prajer, Z. (1969) Swiat Kaktusów, 2: 35–43. “Peyotl-przez ‘mędrca skieƚko’.”

Pratesi et al. 1959 J. Chem Soc. 4062

Prentiss, D.W. & Francis P. Morgan (1895) Therapeutic Gazette, 19: 577–585. “Anhalonium Lewinii (Mescal Buttons). A Study of the Drug with Special Reference to its Physiological Action upon Man.”

Prentiss, D.W. & Francis P. Morgan (1896) Medical Record, (August 22) 258–266. “Mescal Buttons. Anhalonium Lewinii — Hennings (Lophophora Williamsii Lewinii — Coulter).”

Prentiss, D.W. & Francis P. Morgan (1896) Therapeutic Gazette, 20: 4–7. “Therapeutic Uses of Mescal-Buttons.”

Price, D.A. & W.T. Hardy (1953) J. Am. Vet. Med. Assoc., 26, 223

Prieto, Alejandro (1873) Historia, Geografia y Estadistica del Estado De Tamaulipas. Mexico Tip. Escalerillas Num. 13.

Proskurnina & Orekhov (1937) J. Gen. Chem. USSR, 7: 1999 check and insert all a or b

Proskurnina & Orekhov 1937 Bull Soc. Chim. Fr. 4: 1265 check and insert all a or b

Proskurnina & Orekhov 1939 Bull Soc. Chim. Fr. 6: 144.

Proskurnina et al. (1937) Bull Soc. Chim. Fr. 4: 1265 CHECK IF Et al. OR NOT

Psotta, K. et al. (1979) Journal of the Chemical Society, Perkins Transactions I. 1063–1065. “Joubertinamine: A Novel seco-Mesembrane Alkaloid.” (Klaus Psotta, Franz Strelow & Adrian Wiechers)

Pugh, Caecilia Elisabeth Mary & Juda Hirsch Quastel (1937) Biochemical Journal, 31: 2306–2321. “CCLXXXIII. Oxidation of Amines by Animal Tissues.”

Pulse, T.L. & Elizabeth Uhlig (1990) Journal of Advancement in Medicine, 3: 4. “A significant improvement in a clinical pilot study utilizing nutritional supplements, essential fatty acids and stabilized Aloe vera juice in 29 HIV seropositive, ARC and AIDS patients.”

Pummangura & McLaughlin 1982 in the literature meant Pummangura et al. 1982a

Pummangura, S. & J.L. McLaughlin (1981) Journal of Natural Products, 44 (4): 498–499. “Cactus alkaloids. XLVI. 3-Methoxytyramine and Lemaireocereine from Backebergia militaris

Pummangura, S. et al. (1977) Journal of Pharmaceutical Sciences. 66 (10): 1485–1487. “Cactus alkaloids. XXXIII. β-Phenethylamines from the Guatemalan cactus Pilocereus maxonii” (S. Pummangura, D.E. Nichols & J.L. McLaughlin)

Pummangura et al. 1981 JNP 44: 498 in the literature See as Pummangura & McLaughlin 1981

Pummangura, S. et al. (1981) Journal of Natural Products, 44 (5): 614–616. “Cactus Alkaloids. XLVII. β-Phenethylamines from the “Missouri Pincushion”, Coryphantha (Neobessya) missouriensis” (S. Pummangura, J.L. McLaughlin & R.C. Schifferdecker)

Pummangura, S. et al. (1982)a Journal of Natural Products, 45 (2): 224–225. “Cactus Alkaloids. LI. Lack of Mescaline Translocation in Grafted Trichocereus” (S. Pummangura, J.L. McLaughlin & R.C. Schifferdecker)

Pummangura, S. et al. (1982)b Phytochemistry, 21 (9): 2375–2377. “Two Simple Tetrahydroisoquinoline Alkaloid N-oxides from Cacti.” (S. Pummangura, Y.A.H. Mohamed, C.-J. Chang & J.L. McLaughlin)

Pummangura, S. et al. (1982)c Journal of Natural Products, 45: 277–282. “Cactus Alkaloids. XLIX. New Trace Alkaloids (Dehydrosalsolidine and Heliamine) from the Saguaro,
Carnegiea gigantea, and Confirmation by MIKES (MS/MS).” (S. Pummangura, J.L. McLaughlin*, D.V. Davis & R.G. Cooks)

Pummangura et al. (1983) Phytochemistry, “in press” (in the literature) meant Pummangura et al. 1982b.

Pummangura et al. (1983) Journal of Natural Products, (In Press). [S. Pummangura, J.L. McLaughlin, D.V. Davis & R.G. Cooks) [from Lundström 1983: This is not in either the 1983 or 1984 author index under any name listed. Probably 1982c?]

Pummangura, S. et al. (1983)b Phytochemistry, (In Press). (S. Pummangura, Y.A.H. Mohamed, C.-J. Chang & J.L. McLaughlin) (in the literature) meant Pummangura et al. 1982b

Pyne et al. (1986) Chem Soc. Chem. Comm. 1686

Qin, S. et al. (2006).Chin. Tradit. Herb. Drugs, 37, 917–921. “Inhibitory activity of endophytic fungi from three plants of Opuntia Mill.” (S. Qin, K. Xing, S.H. Wu, Q. Zhang, & Y.W. Chen) [from Wu et al. 2008]

Qin, W. et al. (2004) Food Sci./Shipin Kexue 25: 64–66. [Studies on characteristics and inhibition of
polyphenoloxidase (PPO) in Opuntia dillenii] in Chinese with English Abstract. (W. Qin, S. Qian, & R. Zhou) [from Qiu et al. 2007]

Qiu, Y., Yoshikawa, M., Li, Y., Dou, D., Pei, Y., Chen, Y. (2000) J. Shenyang Pharm. Univ./ Shenyang Yaoke Daxue Xuebao 17: 267–268. [A study of chemical constituents of the stems of Opuntia dillenii (Ker-Gaw.) Haw.] in Chinese with English Abstract. (= Chemical Abstracts, 134, 136510j, 2000). [from Qiu et al. 2007]

Qiu, Y. et al. (2002) Chemical & Pharmaceutical Bulletin, 50 (11): 1507–1510. “Constituents with Radical Scavenging Effect from Opuntia dillenii: Structures of New α-Pyrones and Flavonol Glycoside.” (Yingkiun Qiu, Yingjie Chen, Yupin Pei, Hisashi Matsuda & Masayuki Yoshikawa)

Qiu, Y., Chen, Y., Pei, Y., Matsuda, H., Yoshikawa, M. (2003a) J. Chin. Pharm. Sci. 12: 1–5. “New Constituents from the Fresh Stems of Opuntia dillenii.” [from Qiu et al. 2007]

Qiu, Y. et al. (2003b) Yao Xue Xue Bao, 38 (7): 523–525. [The isolation and identification of a new alpha-pyrone from Opuntia dillenii,] Article is in Chinese. (Y.K. Qiu, D.Q. Dou, Y.P. Pei, M. Yoshikawa, H. Matsuda & Y.J. Chen) [from PubMed]

Qiu, Y.K. et al. (2005) Zhongguo Zhong Yao Za Zhi, 30 (23): 1824–1826. [Study on chemical constituents from Opuntia dillenii.] Article is in Chinese. (Y.K. Qiu, D.Q. Dou, Y.P. Pei, M. Yoshikawa, H. Matsuda & Y.J. Chen) [from PubMed]

Qiu, Y.K. et al. (2007) Archives of Pharmacal Research, 30 (6): 665–669. “Two New α-Pyrones and Other Components from the Cladodes of Opuntia dillenii.” (Ying Kun Qiu, Yan Yan Zhao, De Qiang Dou, Bi Xia Xu & Ke Liu)

Quertemont, E. et al. (2005) Progress in Neurobiology, 75 (4): 247–274. “The role of acetaldehyde in the neurobehavioral effects of ethanol: a comprehensive review of animal studies.” (E. Quertemont, S. Tambour & E. Tirelli)

Quastel, Juda Hirsch & Arnold Herbert Maurice Wheatley (1933) Biochemical Journal, 27: 1609–1613. “CCXIX. The Effects of Amines on Oxidations of the Brain.”

Quereshi, M.Y. et al.(1977) Phytochemistry, 16: 477–479. “The Neurolathryogen, α-Amino-β-oxalylaminopropionic Acid in Legume Seeds.” (M. Yasin Quereshi, David J. Pilbeam, Christine S. Evans & E. Arthur Bell)

Raadstroem, M. et al. (1995) Acta Anaesthesiol. Scand. 39: 1084. (M. Raadstroem, J. Bengtsson, S. Edberg, A. Bengtsson, A. C. Loswick and J. P. Bengtsson)

Rabitzsch, G. (1959) Planta Medica, 7 (3): 268–297. “Zur Analytik und Biochemie der p-Hydroxy-β-Phenyl-Alkylamine in Hordeum vulgare L”

Rabusic, Emil & Miroslav Gregor (1967) Spisy Prirodovedecke Fakulty University J.E. Purkkyne v. Brne. 480: 85–92 [from CA (1968) 68: 86944.] “Aminoalkylation of phenol ethers.”

Raffauf, Robert F. (1970) The Handbook of Alkaloids and Alkaloid Bearing Plants. Wiley Inter-Science.

Rahmat A. (2004) Daun jarum tujuh bilah untuk barah, sakit kepala. Malaysia: Utusan Melayu (M) Bhd; 5 December 2004. [from Sim et al. 2010]

Rahwan, Ralf G. (1974) Life Sciences. 15: 617–633. “Speculations on the biochemical pharmacology of ethanol.”

Rahwan, Ralf G. (1975) Toxicology & Applied Pharmacology.

34: 3–27. “Toxic effects of ethanol: Possible role ofacetaldehyde, tetrahydroisoquinolines, and tetrahydro-β-carbolines.”

Rahwan, Ralf G. & Patrick J. O’Neill (1976) Pharmacologist 18: 190. “Absence of formation of brain salsolinol during chronic ethanol administration to mice.”

Rahwan, R.G. et al. (1974) Life Sciences, 14: 1927–1938. “Differential secretion of catecholamines and tetrahydroisoquinolines from the bovine adrenal medulla.” (R.G. Rahwan, P.J. O’Neill & D.D. Miller)

Raiford, L.Chas. & Donald E. Fox (1944) Journal of Organic Chemistry, 9: 170–174. “Condensation of Vanillin Substitution Products With Nitromethane.”

Rajan, K.S. et al. 1976 Bioinorg. Chem 6: 93

Rajotte, P. et al. (1961) Society of Biological Psychiatry, 278–287. “Studies on Mescaline. XII: Effects of prior administration of various psychotropic drugs.” (Paul Rajotte, Herman C.B. Denber, and Dorothy Kauffman)

Ramirez, Fausto A. & Alfred Burger (1950) Journal of the American Chemical Society, 72: 2781–2782. “The reduction of Phenolic β-Nitrostyrenes by Lithium Aluminum Hydride.”

Ranieri, Richard L. & Jerry L. McLaughlin (1975a) Journal of Chromatography, 111: 234–237. “Cactus alkaloids. XXVII. Use of fluorescamine as a thin-layer chromatographic visualization reagent for alkaloids.”

Ranieri, Richard L. & Jerry L. McLaughlin (1975b) Lloydia, 38 (6): 537 (Proceedings.) “Cactus alkaloids XXVIII. β-Phenethylamines and Tetrahydroisoquinolines from
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Ranieri, Richard L. & Jerry L. McLaughlin (1976) Journal of Organic Chemistry, 41 (2): 319–323. “β-Phenethylamines and Tetrahydroisoquinoline Alkaloids from the Mexican Cactus Dolichothele longimamma.

Ranieri, Richard L. & Jerry L. McLaughlin (1977) Lloydia, 40 (2): 173–177. “Cactus Alkaloids. XXXI. β-Phenethylamines and Tetrahydroisiquinolines from the Mexican Cactus
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Ranieri, R.L. et al. (1976) Lloydia, 39 (2-3): 172–174. “Cactus
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Rao, G. Subba (1970) Journal of Pharmacy and Pharmacology,
22: 544–545. “Identity of Peyocactin, an antibiotic from peyote (Lophophora Williamsii ), and Hordenine.”

Raoul, Yves (1936) Thèse Sciences, Paris. “Contribution à l’étude biochimique de l’hordénine.” [From Raoul 1937b]

Raoul, Yves (1937)a Bull. Soc. Chim. biol. (Paris) 19: 675–685. “Sur la formation de l’hordénine par un processus d’allure biologique.”

Raoul, Yves (1937)b Comptes Rendus Hebdomaires des Séances de L’Académie des Sciences, 204: 74–76. “Nouvelle synthèse de l’hordénine.” [from tyrosine]

Rasmussen, Kurt & George K. Aghajanian (1986) Brain Research, 385: 395–400, “Effect of hallucinogens on spontaneous and sensory-evoked locus coeruleus unit activity in the rat: reversal by selective 5-HT2 antagonists.”

Rasmussen, Kurt & George K. Aghajanian (1988) Neuropsychopharmacology, 1: 101–107, “Potency of antipsychotics in reversing the effects of a hallucinogenic drug on locus coeruleus neurons correlates with 5-HT2 binding affinity.”

Ratcliffe, J. & P. Smith (1959) Chemistry and Industry, 925. “Metabolism of Mescaline.”

Rathbun, Richard (1912-1916) Contributions from the United States National Herbarium, 16. “Systematic Investigations of Phanaerogams, Ferns and Mosses.”

Rätsch, Christian (1995) “Eine bisher nicht beschriebene Zubereitungsform von Trichocereus pachanoi.” pp. 267–281 in: Rätsch & Baker (eds.) Jahrbuch für Ethnomedizin und Bewußtseinsforschung. Issue #4.

Rätsch, Christian (1998) Enzyklopädie der Psychoaktiven Pflanzen. Botanik, Ethnopharmakologie und Anwendung. ISBN 3-85502-570-3. AT Verlag, Switzerland. Also as The Encyclopedia of Psychoactive Plants: Ethnopharmacology and its Applications. Rochester: Park Street Press.

Rätsch, Christian (1999) Eleusis, 3: 3–36. “Dall’idromele dell’ispirazione allo spirito del vino: Le bevande alcoliche nella medicina popolare, nella scienze medica e nella farmacologia/ From mead of inspiration to spirit of wine: Alcoholic brews and Folk medicine, medical science & pharmacology.”

Rätsch, Christian & John R. Baker (eds.) Jahrbuch für Ethnomedizin und Bewußtseinsforschung [Yearbook for Ethnomedicine and the Study of Consciousness] Issue #4. VWB: Berlin. ISBN 3-86135-031-9.

Rauh, Werner (1958) Beitrag zur Kenntnis der peruanischen Kakteenvegetation. 361–362. Springer–Verlag Heidelberg

Rauh, Werner (1978) Schöne Kakteen und andere Sukkulenten.

Rauh, Werner & Curt Backeberg 1956 see as Backeberg 1956

Ray, O.S. & C. Ksir (1990) Drugs, Society, and Human Behavior. Times Mirror/ Mosby; St. Louis

Raymond-Hamet, M. (1931) Bulletin de l’Academie Nationale de Médecine (Paris), 105: 46–54. [CA (1932) 26: 1347–1348.] [“The Physiological action of mezcaline, principle alkaloid of Peyotl.”]

Raymond-Hamet, M. (1933)a Archiv für experimentelle Pathologie
und Pharmacologie, 
169: 97–113. “Neue Beobachtungen über die physiologische Wirkung des Mescalins.”

Raymond-Hamet, M. (1933)b Comptes Rendus Hebdomaries des Séances et Mémoires de la Société de Biologie et de ses Filiales Associées, 113: 386–387. “Action de l’hordenine sur le rein à vaisseaux sectionnés puis anastomosés à ceux du cou”

Raymond-Hamet, M. (1933)c Comptes Rendus Hebdomaries des Séances et Mémoires de la Société de Biologie et de ses Filiales Associées, 113: 875–877. “Sur les effets cardiaques de l’hordénine”

Raymond-Hamet 1936 Comptes Rendus, 209: 67 in the literature referred to Raymond-Hamet 1939

Raymond-Hamet, M. (1936) Comptes Rendus Hebdomaries des Séances et Mémoires de la Société de Biologie et de ses Filiales Associées, 121: 112–115. “Sur une propriété physiologique encore inconnue de l’hordénine”

Raymond-Hamet, M. (1939) Comptes Rendus Hebdomaries des Séances de L’Académie des Sciences, 209: 67–69. “L’action nicotinique de l’hordénine n’est pas supprimée par l’introduction dans la molécule d’un second oxyhydrile phénolique, celui-ci en position méta.” 

Raymond-Hamet, M. (1940) Comptes Rendus Hebdomaries des Séances et Mémoires de la Société de Biologie et de ses Filiales Associées, 133: 570–572. “L’oxytyramine doit-elle être tenue pour une amine véritablement sympathomimétique?”

Read, J. & I.G.M. Campbell (1930) J. Chem. Soc. 2682.

Rebut, [Pierre] catalog (nd) Rebut Catalogue de Cactées et Plantes Grasses Diverses. [As cited in Lewin 1894 & Schultes 1940] (1894 page 5; according to Grym 1997) [Anhalonium jourdanianum Rebut or Anhalonium jourdanianum Hort.?]

Rebut, Pierre (1905) Monatschr. f. Kakteenk. 15: 122 [Echinocactus jourdanianus (Rebut) Rebut ] [From Schultes 1940] [Grym 1997 gives this citation as C.A. Maass 1905]

Reggiani, A. et al. (1980) Substance and Alcohol Actions/Misuse, 1: 151–158. “Role of dopaminergic-enkephalinergic interactions in the neurochemical effects of ethanol.” (Reggiani, M.L. Barbaccia, P.F Spano & M. Trabucchi)

Reich (1991) Horticulture 69 (1): 58–59. “Grafting.”

Reichel-Dolmatoff, G. (1978)a Beyond the Milky Way: Hallucinatory Images of the Tukano Indians. Latin American Studies No. 42.

Reichel-Dolmatoff, Gerardo (1978)b “Drug Induced optical Sensations and Their Relationship to Applied Art among Some Colombian Indians.” 289–304, in Michael Greenhalgh & Vincent McGraw (eds.) Art and Society. Duckworth: London.

Reichert, Benno (1936) German Patent 629,313 April 30 1936; [CA (1936) 30: 4875]

Reidlinger, Thomas J. (ed.) (1997) The Sacred Mushroom Seeker. Tributes to R. Gordon Wasson. Park Street Press. ISBN 0-89281-338–5. [1990 by Timber Press]

Reinberg, P. (1921) Journal de la Société des Américanistes Paris, 13: 25–54, 197–216. “Contributión a l’étude des biossons toxiques des indiens du nord-ouest de l’Amazone: l’ayahuasca, le yagé, le huánto. Étude comparative toxico-physiologique d’une experience personelle.”

Reko, Blas Pablo (1928) Memorias y Revista de la Sociedad Cientifica”Antonio Alzeta”. (Mexico), 49: 379. “Alcaloide y Glucosidos en Plantas Mexicanas.”

Reko, Blas Pablo (1928) Mem. Soc. Cient. “Antonio Alzate” 49: 380. [From Neal et al. 1972]

Ressler, Bob R. (2000) Cactus & Succulent Journal, (US) 72 (6): 309–312. “Trichocereus cuzcoensis – A hardy Peruvian columnar cactus.”

Retamozo, Bióloga Edith (2000) Quepo, 16: 28–32. “Formas Polinicas de Cactáceae en Arequipa.”

Reti, Ladislao (1933)a Comptes Rendus des séances de la Société de Biologie et de ses filiales, 114: 811–814. [(1933) Rev. Soc. Argentina Biol. 9: 344] “Sur les alcaloïdes de la cactacée Trichocereus candicans (Br et Rose)”

Reti, Ladislao (1939) Atti. X. Congr. int. Chim. Roma, 5: 396–405. “Nuovi alcaloidi di cactacee argentine” (Paper presenting his preliminary report on T. terscheckii.)

Reti, Ladislao (1947) Ciencia e Investigación. Revista Patrocinada por la Asociación Argentina, October: 405–411. “Alcaloides de las cactáceas y substancias naturales relacionadas.”

Reti, Ladislao (1950) Forstschritte der Chemie Organischer Naturstoffe (Progress in the Chemistry of Organic Natural Products.) 6: 242–289. “Cactus Alkaloids and Some Related Compounds”

Reti, Ladislao (1953) “β-Phenethylamines.” pp. 313–348, (Chapter 22) in: R.H.F. Manske & H.L. Holmes (eds.) The Alkaloids. Chemistry and Physiology. Volume III.

Reti, Ladislao (1954)a “Simple Isoquinoline Alkaloids”, p. 7–21, (Chapter 26), in: R.H.F. Manske & H.L. Holmes (eds.) The Alkaloids. Chemistry and Physiology. Vol 4.

Reti, Ladislao (1954)b “Cactus Alkaloids” pp. 23–28, (Chapter 27), in: R.H.F. Manske & H.L. Holmes (eds.) The Alkaloids. Chemistry and Physiology. Vol 4.

Reti, L & R.L. Arnolt (1935) Actas y trabajo del V. Congr. Nac. de Medicina, Rosario, 3: 39. “Alcaloids del Trichocereus lamprochlorus (Lem.) Britton and Rose”

Reti, Ladislao & Juan A. Castrillón (1951) Journal of the American Chemical Society, 73 (4): 1767–1769. “Cactus alkaloids. I. Trichocereus tersheckii (Parmentier) Britton and Rose”

Reti, L. et al. (1935) Comptes Rendus des séances de la Société de Biologie et de ses filiales, (Société de Biologie de Rosario 25 Octobre 1934) 118: 591–593. [(1934) Rev. Soc. Argentina biol. 10: 437] “Sur un alcaloïde du Cereus coryne Salm. (1850)” (L. Reti, R.I. Arnolt & F.P. Ludueña)

Reutter, L. (1924) Schweizerische Apotheker-Zeitung, 62: 441–443. “Du Peyolt [sic], comme drogue sensorielle.”

Revel, Jean-François (1977) The Totalitarian Temptation. [Hardcover; Doubleday: NY/ Paperback; Penguin: NY (Again in 1978] 311 pages.

Reyna Pinedo, Víctor & Flores Garcés, José (2001) Quepo, 15: 28–37. “El uso del “San Pedro” (Echinopsis pachanoi) en medicina tradicional peruana.”

Reynolds, P.C. & E.J. Jindrich (1985) Journal of Analytical Toxicology, 9: 183–184. “A mescaline associated fatality.”

Rhodes, Willard (1958) Journal of the International Folk Music Council, 10: 42–49. “A study of musical diffusion based on the wandering of the opening peyote song.”

Riccobono, Vincenzo (1909) Bollettino delle R[eale] Orto Botanico di Palermo, 8: 215–266. “Studii sulle Cattee del R. Orto Botanico di Palermo.”

 Aporocactus flagelliformis 260–261

 Cereus grandiflorus 249–250

 Eriocereus jusberti 240

 Eriocereus tephracanthus 244–245

 Myrtillocactus geometrizans 224–225

 Pilocereus euphorbioides 254–255

 Piptanthocereus beneckei 226–227

 Piptathocereus jamacaru 229–230

 Piptanthocereus peruvianus 232–233

 Stenocereus stellatus 253–254

 Trichocereus macrogonus 236–237

 Trichocereus spachianus 237–238

Riccobono, Vincenzo (1909) Bollettino delle R[eale] Orto Botanico di Palermo, 8: 244 -245. “Sp. 8. ° Eriocereus tephracanthus (BERG. l. c. p. 74).”

Riccobono, Vincenzo (1909) Bollettino delle R[eale] Orto Botanico di Palermo, 8: 236–237. [i.e. Bollettino del R. Orto Botanico e Giardino Coloniale] “Sp. 1. ° Trichocereus macrogonus (BERG. 1. c, p. 83).”

Rice, W.B. & J.D. McColl (1960) Archives Internationales de Pharmacodynamie et de Thérapie, 127: 249–259. “Antagonism of psychotomimetic agents in the conscious cat.“

Richardson, A.B. et al. (1891) Cincinnati Lancet and Clinic 27: 829. “Cactus grandiflorus as a Heart Tonic.” (A.B. Richardson, J.C. Oliver & L.C. Colter)

Richardson, A.B. et al. (1891) Cincinnati Lancet and Clinic, 27: 828–829. “Cactina, a New Cardiac Tonic.” (A.B. Richardson, J.C. Oliver & L.C. Colter)

Richardson, D.A. (1896) The Denver Times, 16 (6): 214–217. “Anhalonium Lewinii – Mescale Button – A Report of Five Cases in Which the Tinture was Exhibited in Four-Drop Doses Daily.”

Richardson, Mick (1978) Biochemical Systematics and Ecology, 6: 283–286. “Flavonols and C-Glycosylflavonoids of the Caryophyllales.”

Richter, Derek (1938) Biochemical Journal, 32: 1763–1769. “CCXXIX. Elimination of Amines in Man.”

Rico-Bobadilla, A.C. et al. (2001) XXXII Congreso Nacional de Microbiología. Guanajuato, Guanajuato. México. Abril 3–5. “Efecto antimicrobiano del extracto liofillizado de músaro (Lophocereus schottii).” (AC Rico-Bobadilla, OLE Gassós & FA Félix) [from Garza Padrón 2010]

Riedlinger, Thomas (ed.) (1990) The Sacred Mushroom Seeker. Tributes to R. Gordon Wasson. Park Street Press: Rochester. ISBN 0-89281-338-5.

Rietschel, Hans G. (1937)a Naunyn-Schmiedebergs Arch. exp. Path. Pharmakol. 186: 387–408. “Zur Pharmakologie des Hordenins.”

Rietschel, Hans G. (1937)b Klinische Wochenschrift 16 (20): 714–715. “Zur Pharmakologie des Hordenins.”

Rigal-Cellier, Bernadette (2004) The Peyote Way Church of God: Native Americans v. New Religions v. the Law.

Riggins, R.M. & P.T. Kissinger (1976) Journal of Agricultural and Food Chemistry, 24: 900. “Identification of salsolinol as a phenolic component in powdered cocoa and cocoa-based products.”

Riggin, Ralph M. & Peter T. Kissinger (1977) Analytical Chemistry, 49 (4): 530-.533 “Determination of Tetrahydroisoquinoline Alkaloids in Biological Materials with High Performance Liquid Chromatography.”

Riggin, R. M. et al. (1976) Journal of Agricultural and Food Chemistry, 24: 189–191. “Identification of salsolinol as a major dopamine metabolite in the banana.” (R.M. Riggin, M.J. McCarty & P.T. Kissinger)

Říha, J. & R. Šubík (1979) Aztekia 1: 9–14. “Lophophora diffusa.

Ríha, J. & R. Šubík (1981) The Illustrated Encyclopedia of Cacti & Other Succulents. Artia, Prague. ISBN 0-7064-1492-6.

Říha, Jan (1996) Kaktusy, 32: 70–73. “Lophophora diffusa var. koehresii.“

Remington, J.P. et al. (eds.) (1918) The Dispensatory of the United States, 20th edition. (Joseph P. Remington, Horatio C. Wood, & others) [From the online version at The Southwest School of Botanical Medicine http://www.swsbm.com]

Rimington et al. (1938) J. Vet. Sci. Animal Ind. 9: 187. [CA (1938) 32: 42799]. [From Merck 9th] Also cited as Rimington, C. & G.C.S. Roets (1937) Onderstepoort Journal of Veterinary Science and Animal Industry 9: 187–191. “Notes upon the isolation of the alkaloidal constituent of the drug ‘channa’ or ‘kougoed’ (Mesembryanthemum anatomicum and Mesembryanthemum tortuosum).” [From Smith 1996] (Unable to obtain a copy.)

Rinaldi, Franco & H.E. Himwich (1955) Journal of Nervous and Mental Disease, 122 (5): 424–432. “The cerebral electroencephalographic changes induced by LSD and mescaline are corrected by frequel.”

Rinkel, Max (1956) “Biochemical Reflections on the Psychosis Problem.” in L. Cholden (ed.) Lysergic Acid and Mescaline in Experimental Psychiatry. New York: Grune and Stratton.]

Rinkel, Max (1957) Journal of Nervous and Mental Disease, 125 (3): 424–427. “Pharmacodynamics of LSD and Mescaline.”

Rinkel, Max (1965) The Presidential address: the LSD movement in America. (Paper read at Soc. Biol. Psychiat., New York City April-May, 1965.)

Rinkel, Max & H.C.B. Denber (eds.) (1958) Chemical Concepts of Psychosis. NewYork: McDowell.

Rinkel, Max, et al. (1952) American Journal of Psychiatry, 108: 572–578. “Experimental Schizophrenia-like symptoms.” (Max Rinkel, H.J. Deschon, R.W. Hyde & H.C. Solomon)

Rinne, U.K. & V. Sonninen (1967) Nature, (London) 216: 489.

Ritter, Friedrich (1958) “Die von Curt Backeberg in “ Descriptiones Cactacearum novarum “ veröffentlichten Diagnosen “ n e u e r “ peruanischer Kakteen nebst grundsätzlichen Erörterungen über taxonomische und nomenklatorische Fragen.” Friedrich Ritter Verlag, Hamburg.

Ritter, Friedrich (1962) Kakteen und andere Sukkulenten, 13 (10): 165–167. “Trichocereus fulvilanus Ritter spec. nov. “

Ritter, Friedrich (1966) Cactus (Paris). Organe de l’Association Française des Amateurs de Cactus et Plantes Grasses. Paris. 21 (87): 13–14. “Trichocereus crassicostatus Ritter spec. nov.”

Ritter, Friedrich (1966) Cactus (Paris). Organe de l’Association Française des Amateurs de Cactus et Plantes Grasses. Paris. 21(87): 14–15. “Trichocereus scopulicola Ritter spec. nov.” [Using the citation “Cactus, Paris, No. 87. Page 14” (obtained from the Index Kewensis CD-ROM), we were unsuccessful in locating this paper despite over 5 years of active effort and the help of numerous professionals. Interlibrary loan insisted repeatedly that no such journal existed. Our thanks to Dr. M. Terry for his help in finally obtaining a copy.]

Ritter, Friedrich (1980) Kakteen in Südamerika. Argentinien/Boliviens Vol. 2: 375–856. (Trichocereus: 437–456) F.Ritter/self-published

Ritter, Friedrich (1981) Kakteen in Sudamerika. Peru. Vol. 4: 1239–1692. (Trichocereus: 1324–1329) F.Ritter/self-published

Rivas, Augustin. “Canto Musica Ayahuasca en la Silva de Peru: Agustin Rivas.” Tape available through the Basement Shaman.

River, Liliana & Joseph Rael (1984) Beautiful Painted Arrow: A Medicine Story. Path-ways: Virginia Beach. [P.O.Box 4308/ 23454] No ISBN. 129 pages.

Rivier, Laurent & Jan-Erik Lindgren (1972) Economic Botany, 26: 101–129. “ “Ayahuasca”, the South American Hallucinogenic Drink: an Ethnobotanical and Chemical Investigation.” [Epiphyllum]

Rivier, Laurent & Paul-Émile Pilet (1971) L’Anneée Biologique 10 (3-4): 129–149. “Composés Hallucinogènes Indoliques Naturels.”

Robb, George L. (1957) Botanical Museum Leaflets. Harvard University, 17 (10): 265–316 “The Ordeal Poisons of Madagascar and Africa.”

Robert (Bob) Schick (2003) Echinopsis Revisited. PDF posted on Cactus etc (http://www2.labs.agilent.com/bot/cactus_home).

Roberti, C.E. & H. Heymann (1937) Rassegna di studi psichiatrici 26: 245, 353. “Dell’ allucinazioni.”

Robinson, G. (1954) in H.A. Abramson, (ed.) Problems of Consciousness, 5th Conference, 1954, Princeton. J. Macy, Jr. Foundation.

Robinson, John C, Jr., & H.R. Snyder (1955) “β-Phenethylamine (Phenethylamine)” pp. 720–722, in E.C. Horning (ed.) Organic Synthesis. Collective Volume III.

Robiola, P.F. (1955) Minerva Medica, 46 (103): 1975–1976. [A New Drug Compound with Cereus grandiflorus Mill., a Mexican Cactus with Cardiotonic Action] (article is in Italian) [From Aardvark 2006]

Robles, Clemente & José Gomez Robleda (1931) Anales del Instituto de biologia de la Universidad Nacional Autonoma de México. 2 (1): 15–46. “Trabajo inicial acerca de la acción fisiológica del chlorhidrato de peyotina.”

Roca, Juan (1930) Anales del Instituto de Biologia de la Universidad Nacional de México, 1 (3): 204. “Nota Preliminar Acerca del Estudio Quimico del Pachycereus Marginatus.

Roca, Juan (1931) Anales del Instituto de Biologia de la Universidad Nacional de México, 2 (2): 133–137. “Estudio Quimico Preliminar del Pachycereus Marginatus.”

Roca, Juan (1932) Anales del Instituto de Biologia de la Universidad Nacional de México, 3 (1): 19–23. “Analisis Quimico del Pachycereus Marginatus.”

Rodríguez, G.R.G, et al. (2008) VI Simposio Internacional sobre Flora Silvestre en Zonas Áridas. La Paz, B.C.S., Marzo 12–15. “Actividad biológica de Ariocarpus kotschoubeyanus (Lemaire), Ariocarpus retusus (Scheidweiler) y Fouquieria splendens (Engelmann).” (GRG Rodríguez, SMJ Verde, CA Oranday, RME Morales, MC Rivas, GMA Núñez & NJF Treviño) [from Garza Padrón 2010]

Rodriguez, Miguel Angel (2010) “Preparación necesaria para la Sanación con Híkuri o Peyote, Ayahuasca y San Pedro (Huachuma).” Paper from 2010 Congreso Internacional de medicina traditcional y salud pública. “El peyote, medicina tradicional o droga lúdica” 20–23 October, Toluca, México

Roitman, M.F. et al. (2002) Journal of Neuroscience, 22: 225-? “Induction of a Salt Appetite Alters Dendritic Morphology in Nucleus Accumbens and Sensitizes Rats to Amphetamine.” (Mitchell F. Roitman, Elisa Na, Gregory Anderson, Theresa A. Jones, & Ilene L. Bernstein) See also re: article in Journal of Neuroscience. http://www.sciencedaily.com/releases/2002/06/020604073144.htm “Rats Depleted Of Salt Become Sensitized To Amphetamine, Show Unusual Growth Of Brain Cells.”

Rojas Aréchiga, Mariana (2008) Ciencias, 91: 44–49. “El Controvertido Peyote”

Romariz, I.C. (1946) Portugaliae Acta Biol. Ser. A. 1: 235–250. [“Unusual carotenoids in young leaves.”] [From 1949 CA 43: 1836i-1837a] See also 1947 Biological Abstracts, 21: 1511.

Romero, M.L. (1983) J. Chromatogr. 281: 245

Rose, Joseph Nelson (1899) Contributions from the US National Herbarium, 5 (4): 209–259. “Notes on Useful Plants of Mexico.”

Roseghini, M. et al. (1976) Comparative Biochemistry and Physiology. Part C, Comparative Pharmacology, 54 (1): 31–43. “Indole-, imidazole- and phenyl-alkylamines in the skin of one hundred amphibian species from Australia and Papua New Guinea. “ (M. Roseghini, V. Erspamer & R. Endean)

Roseghini, M. et al. (1976) Z. Naturforsch. C. 31: 118

Roseghini, M. et al. (1988) Comparative Biochemistry and Physiology. Part C, Comparative Pharmacology, 91 (2): 281–286. “Biogenic amines and active peptides in the skin of fifty-two African amphibian species other than bufonids.” (M. Roseghini, G. Falconieri Erspamer & C. Severini)

Roseghini, M. et al. (1989) Comparative Biochemistry and Physiology. Part C, Comparative Pharmacology,  94 (2): 455–460. “Biogenic amines and active peptides in extracts of the skin of thirty-two European amphibian species.” (M. Roseghini, G. Falconieri Erspamer, C. Severini & M. Simmaco)

Roseman, Bernard (1968) The Peyote Story. The Indian Mind Drug. Wiltshire: Hollywood.

Rose-Munch, F. et al. (2000) Inorganica Chimica Acta, 300-302: 693–697. “Mescaline synthesis via tricarbonyl (η6-1,2,3-trimethoxybenzene)chromium complex.” (Françoise Rose-Munch, René Chavignon, Jean-Philippe Tranchier, Vanessa Gagliardini & Eric Rose)

Rosenberg, H. & A.G. Paul (1969) Tetrahedron Letters, 13: 1039–1042. “Dolichotheline, a novel imidazole alkaloid from Dolichothele sphaerica” [The only alkaloid they reported in this paper.]

Rosenberg, H. & A.G. Paul (1970) Phytochemistry, 9 (3): 655–657. “The isolation and biosynthesis of dolichotheline” [From Dolichothele sphaerica]

Rosenberg, H. & S.J. Stohs (1974) Phytochemistry, 13: 1861–1863. “The Utilization of Tyrosine For Mescaline and Protein Biosynthesis in Lophophora Williamsii.”

Rosenberg, H. & S.J. Stohs (1976) Phytochemistry, 15 (4): 501–503. “Effects of histidine decarboxylase inhibitors on the production of an aberrant alkaloid in Dolichothele sphaerica.”

Rosenberg, H. et al. (1964) Psychopharmacologia, 5: 217–227. “The effect of N,N-dimethyltryptamine in human subjects tolerant to lysergic acid diethylamide.”

Rosenberg, H. et al. (1967) Lloydia, 30 (1): 100–105. “The Cactus Alkaloids. III. Phenylalanine, DOPA and DOPAmine as precursors to Mescaline in Lophophora Williamsii.”

Rosenberg, H. et al. (1969) Lloydia, 32 (3): 334–338. “The Biosynthesis of Mescaline in Lophophora Williamsii.” (H. Rosenberg, K. L. Khanna, M. Takido & A. G. Paul)

Rosenberg, H. et al. (1974) Phytochemistry, 13 (5) 823–828. “Directed biosynthesis of unnatural alkaloids in Dolichothele sphaerica.” (Harry Rosenberg, Sidney J. Stohs & Ara G. Paul)

Rosenberg et al. 1976 in the literature See as Rosenberg & Stohl 1976

Rosenmund, Karl W. (1909) Berichte der Deutschen Chemischen Gesellschaft, 42 (4): 4778–4783. “Über p-oxyphenyl-äthylamin”

Rosenmund, Karl W. (1910) Berichte der Deutschen Chemischen Gesellschaft, 43: 306. “Die Synthese des Hordenine, eines Alkaloids aus Gerstenkeimen, und über α-p-Oxyphenyl-äthylamin.”

Rosenthaler, L. (1931) Pharmaceutische Zeitung, 76: 653–654. “Beitrage zum Nachweis organischer Verbindungen. IV. Mikrochemische Reaktionen des Mezcalins.” [From Reti 1950] Listed elsewhere as “Détection de composes organiques. Réaction microchemiques de la mescaline.” and “Detection of organic compounds: microchemical reactions of mescalin.”

Rosenthaler, L. (1935) Toxikologische Mikroanalyse. p. 15. Borntraeger, Berlin.

Rösler, H. et al. (1966) Phytochemistry, 5: 189–192. “The Flavonoid Pigments of Opuntia lindheimeri.” (Heinz Rösler, Ursula Rösler, Tom. J. Mabry & Jacques Kagan)

Rosler, H. et al. (1978) Lloydia, 41 (4): 383–384. “The Isolation of 6-Methoxyharmane From Grewia mollis.” (Heinz Rosler, Helene Framm & Ralph N. Blomster)

Rösner, P. et al. (2007) Mass Spectra of Designer Drugs, Including Drugs, Chemical Warfare Agents, and Precursors, Vol. 2. (P. Rösner, T. Junge, F. Westphal & F. Fritsch) Wiley-VCH Verlag/Weinheim. 2067 pages.

Ross (1978) Alcoholism: Clin. Exp. Res. 2: 139–143.

Ross, Brian & Jill Rackmill (2000) ABC 20/20, 18 February. “Homicide Within the DEA” See http://www.abcnews.go.com/onair/2020/2020_000217_ross_feature.html

Roth, R.H. & N.J. Giarman (1970) Phytochemistry, 19: 1087–1093. “Natural Occurrence of Gamma-Hydroxybutrate in Mammalian Brain.”

Rotondo, H. (1943) Revista de neuropsiquiatria (Lima), 6: 58–143. “Fenomenología de la intoxicación mescalinica y análisis funcional del pensamiento en su decurso.”

Rouhier, Alexandre (1925) Revue metapsychique, pp. 144–145. “Phénomènes de metagnomie expérimentale observés au course d’une experience fait avec le peyotl.”

Rouhier, Alexandre (1926) Thesis, Doct. Pharm. Facultié de Pharmacie de Paris. Monographie du Peyotl.

Rouhier, Alexandre (1927)a La Plante qui fait les yeux émerveillés. LePeyotl (Echinocactus williamsii). Gaston Doin & Cie, Paris. [Also in 1926 by G. Tredaniel: Paris) [See also (1989) Éditions de la Maisnie. 409 pp. ISBN 2-85707-332-1.]

Rouhier, Alexandré (1927)b Les Plantes divinatoires. Doin, Paris. (Huachuma page 12).

Rouhier, Alexandre (1988) “L’ebbrezza peyotica (Studio sull’esperienza di Havelock Ellis).” pp. 69–79 in J.C. Bailey & J.P. Guimard L’esperienza allucinogena. Dedalo: Bari.

Rouhier, Alexandre (1996) Die Hellsehen hervorrufenden Pflanzen. VWB: Berlin (reprint)

Round Table. Psychodynamic and Therapeutic Aspects of Mescaline and Lysergic acid Diethylamide. See Denber & Rinkel (eds.) 1957.

Roush, R. et al. (1985) Analytical Chemistry, 57: 109–114. “Search for New Alkaloids in Pachycereus weberi by Tandem Mass Spectrometry.” (Robin A. Roush, R. Graham Cooks, Stephanie A. Sweetana & Jerry L. McLaughlin)

Rowley, Gordon D. (1974) IOS Bulletin, 3(3): 93–99. “Reunion of the Genus Echinopsis

Rowley, Gordon D. (1978) The Illustrated Encyclopedia of Succulents. Crown Publ, New York 1978. ISBN # 0-517-53309-X. Very nice book but hardly encyclopedic.

Rubini (1864) Therapeut. et Pathog. (October): 268-?. “Pathogénésie du Cactus grandiflorus observée sur l’homme sain et confirmée sur le malade.” [From Hobschette 1929]

Ruchirawat et al. (1984) Synth. Commun. 14: 1221

Ruck, C.A.P. et al. (1979) Journal of Psychoactive Drugs, 11 (1–2): 145–146: “Entheogens.” (Carl A.P. Ruck, Jeremy Bigwood, Danny Staples, Jonathan Ott & R. Gordon Wasson)

Ruckebusch, Y. et al. (1965)a Comptes Rendus des séances de la Société de Biologie et de ses filiales, 159 (4): 911–914. “Synergie et antagonisme de l’activité hyperthermisante de la mescaline.” (Y. Ruckebusch, M.L. Grivel & M. Roche)

Ruckebusch, Y. et al. (1965)b Comptes Rendus des séances de la Société de Biologie et de ses filiales, 159: 1745–1748. “Parallélisme des effets des psychodysleptiques majeurs sur da toxicité de groupe et le taux cérébral en sérotonine.” (Y. Ruckebusch, M. Roche & D. Schurch)

Rudgley, Richard (1995) Addiction 90: 163–164. “The Archaic Use of Hallucinogens in Europe: An Archaeology of Altered States.”

Ruiz de Alarcón See as De Alarcon

Ruiz, S.O. et al. (1973) An. Asoc. Quim. Argen. 61: 41. “Alcaloides de Cactaceas: Gymnocalycium schickendantzii (Weber) Br. & R, y Cereus aethiops Haworth.” (S.O. Ruiz, G. Neme, M. Nieto & A.T. D’Arcangelo)

Rümpler, Theodor (1886) Carl Friedrich Förster’s Handbuch der Cacteenkunde Second ed. Leipzig: Verlag von Im. Tr. Woller. Page 233. [from Grym 1997 & Anderson 1980] 2nd ed. is given as 1885 in Britton & Rose and also by Croizat. Page 712: Cereus tephracanthus bolivianus Weber; Page 688: Pilocereus terscheckii Rümpler; Page 827: Echinocereus strigosus var. spinosior Rümpler & Echinocereus strigosus var. rufispinus Rümpler

Rusby, H. (1894) Bulletin of Pharmacy, 8: 306.

Rusby, H.H. (1888) Bulletin of Pharmacy, 2: 126. “A. Lewinii.” [From LaBarre]

Rusby, H.H. (1894) Bulletin of Pharmacy, 8: 306. “Mescal Buttons.” [From Grym 1997 & LaBarre]

Rusby, H.H. (1894) Bulletin of Pharmacy, 8: 306. “Mescal Buttons.” [From Grym 1997 & LaBarre]

Rusby, H.H. (1903) Reference Handbook of the Medical Sciences, 6: 456. “Mescal Buttons.” [from LaBarre]

Saag, L.M.K. et al. (1975)  in the literature meant Mindt et al. 1975. (L.M.K. Saag was created by a lack of a comma in “Lothar Mindt Karl Saag”.)

Sacred Succulents’ Grafting Guide was available from Sacred Succulents, POBox 781, Sebastopol, California, 95473. Catalog $2. (Cost was $6 in 1999.)

Safford, William E. (1908) Washington Annual Report Smithsonian Institution of Sciences, 1908. 525–563 (with 15 plates; one of the plates faces page 525.) “Cactaceae of Northeastern and Central Mexico, Together With a Synopsis of the Principal Mexican Genera.”

Safford, William E. (1915) Journal of Heredity. 6: 291–311. “An Aztec Narcotic.”

Safford, William E. (1916)a Annual Report. Smithsonian Institution, 1916: 387–424, plus 17 plates. “Narcotic Plants and Stimulants of the Ancient Americans.”

Safford, William E. (1916)b Washington Academy of Sciences, 6: 547–562. “Identity of cohoba, the narcotic snuff of ancient Haiti.”

Safford, William E. (1921) Journal of the American Medical Association, 77 (16): 1278–1279. “Peyote, the Narcotic Mescal Button of the Indians.”

de Sahagún, Bernadino (1829 & 1830) (finished circa 1578) Historia general de las cosas de Nueva España (ed. C.M. de Bustamante) 2: 366 & 3: 241 [3 volumes: 1829–1830; Mexico] Later republished as the Florentine Codex. The Franciscan friar Bernardino de Sahagún. Bernardino originally titled it: La Historia General de las Cosas de Nueva España (in English: the General History of the Things of New Spain) Bernadino de Sahagún [1490–1590]

de Sahagún, Bernadino (1880) Histoire générale des chosas de la Nouvelle-Espagne (tr. & ed. by D. Jourdanet & Rémi Siméon) Paris.

de Sahagún, Bernadino (1932) A History of Ancient Mexico by Fray Bernardino de Sahagún, Vol. 1 (tr. by Fanny R. Bandlier) Nashville.

de Sahagún, Bernadino (1938) Historia general de las cosas de Nueva España (5 Volumes) P. Robredo: México.

Sahu, N.P. et al. (1974) Phytochemistry, 13: 529–530. “A new saponin of oleanolic acid from Pereskia grandifolia.” (N.P. Sahu, N. Banerji & R.N. Chakravarti)

Sai-Halász, A. (1962) Experientia, 18: 137–138. “The effect of Antiserotonin on the Experimental Psychosis Induced by Dimethyltryptamine.”

Sailer & Stumpf (1957) Archiv für Experimentelle Pathologie und Pharmakologie, 230: 378.

Salcedo, Mario B. (1986) Un Herbolario de Ch’ajaya Devela sus Secretos. Ediziones Senpas: La Paz, Bolivia. 165 pages.

Saleem, R. et al. (2005) Biological & Pharmaceutical Bulletin, 28 (10): 1844–1851. “Hypotensive activity, toxicology and histopathology of opuntioside-I and methanolic extract of Opuntia dillenii.” (Rubeena Saleem, Mohammad Ahmad, Aisha Azmat, Syed Iqbal Ahmad, Zareen Faizi, Lubna Abidi & Shaheen Faizi)

Saleem, M. et al. (2006) Phytochemistry, 67: 1390–1394. “Secondary metabolites from Opuntia ficus-indica var. saboten.” (Muhammad Saleem, Hyoung Ja Kim, Chang Kyun Han, Changbae Jin & Yong Sup Lee)

Salerno, Enrique V. & Alberto Tallaferro (1957) Semana Médica (Buenos Aires), 110 (1): 47–48, 52. [Chemical Abstracts (1957) 51: 8997b.] [“Mescaline, D-lysergic acid diethylamide, and menstrual function.”]

Salm-Dyck (1834) Cact. Hort. Dyck 1834: 334 [Cereus strigosus] [From Britton & Rose]

Salm-Dyck, Jos. de (1845) Cacteæ in Horto Dyckensi cultæ anno 1844. Additis tribuum generumque characteribus emendatis. Parisiis e Typis Crapelet. 51 pages.

 Cereus strigosus: 27

 Cereus candicans : 27

 Cereus chilensis: 27

 Cereus chilensis f. fulvibarbis: 27

 Cereus chilensis f. brevispinulus = C. quintero: 27

 Cereus gladiatus: 28

Salm-Dyck, Jos. de (1850) Cacteæ in Horto Dyckensi cultæ anno 1849. Secundum tribus et genera digestæ, additis adnotationibus botanicis characteribusque specierum in enumeratione diagnostica cactearum doct. Pfeifferi non descriptarum. Bonnæ apud Henry & Cohen. Typis C. Georgii. 266 pages + 1 page addendum.

 Cereus candicans : 51

 Cereus bridgesii: 48 & 208–209

 Cereus candicans : 43

 Cereus chilensis : 44 & 198

 Cereus chiloensis 44

 Cereus eburneus : 47

 Cereus Forbesii: 47 & 206

 Cereus fulvibarbis 44

 Cereus fulvispinus 46

 Cereus gladiatus 48

 Cereus grandiflorus 51 & 216

 Cereus intricatus 43 & 194

 Cereus lamprochlorus 43 & 195

 Cereus longispinus 44 & 196

 Cereus macrogonus 46 & 203

 Cereus nigricans 46 & 202

 Cereus spachianus : 43 & 194

 Cereus tenuispina 62

 Cereus Terscheckii 46

 Cereus tetragonus 47

 Cereus validus: 48

 Echinopsis bridgesii: 38 & 181

 Echinopsis valida: 39 & 181

Salm-Dyck 1909 (in the literature) refers to Riccobono 1909.

Salmoiraghi, Gian Carlo & Irvine H. Page (1957) Journal of Pharmacology and Experimental Therapeutics, 120 (1): 20–25. “Effects of LSD-25, BOL 148, Bufotenine, Mescaline and Ibogaine on the Potentiation of Hexobarbitol Hypnosis Produced by Serotonin and Reserpine.” [Reported that the entheogenically inactive BOL 148 could be enabled to be active when given with large doses of serotonin.]

Salomon, Kurt & Albert F. Bina (1946) Journal of the American Chemical Society, 68: 2403. “Ultraviolet Absorption Spectra of Mescaline Sulfate and β-Phenethylamine Sulfate.”

Salomon, Kurt et al. (1947) Federation Proceedings. Federation of American Societies for Experimental Biology, 6: 367–368. “Investigation of the psycho-chemical basis of visual hallucinations produced by mescaline.” [Abstract of a paper presented to the 37th Annual Meeting: the American Society for Pharmacology and Experimental Therapeutics.] (Kurt Salomon, Thomas Thale and Beverly Westscott [sic?] Gabrio)

Salomon, Kurt et al. (1949) Journal of Pharmacology and Experimental Therapeutics, 95 (4): 455–459. “A study of mescaline in human subjects.” (Kurt Salomon, Beverly Wescott Gabrio and Thomas Thale)

Salt, T.M. et al. (1987) Phytochemistry, 26 (3): 731–733. “Dominance of Δ5-Sterols in Eight Species of the Cactaceae.” (Thomas A. Salt, Joel E. Tucker & John H. Adler)

Samorini, Giorgio (1998)a Allucinogeni, empatogeni, cannabis. Bibliografia italiana commentata, Grafton 9: Bologna. 165 pp.

Samorini, Giorgio (1998)b Eleusis n.s., 1: 87–108. “Gli “alberi-fungo” nell’arte cristiana.” / “Mushroom-Trees” in Christian Art.”

Sanchez, Victor (1996) Toltecs of the New Millenium. Bear and Co. (Ingram) ISBN 1-879181-35-5. 228 pages.

Sandler et al. 1982 in Bloom

Sandler, M. et al. (1973) Nature, 241: 439–443. “Tetrahydroisoquinoline alkaloids: in vivo metabolism of l-DOPA in man.” (M. Sandler, S.B. Carter, K.R. Hunter & G.M. Stern)

Sandoval, A. et al. (1957) Journal of the American Chemical Society, 79: 4468–4472. “Terpenoids. XXX. The Structure of the Cactus Triterpene Chichipegenin.” (A. Sandoval, A. Manjarrez, P.R. Leeming, G.H. Thomas & Carl Djerassi)

Sands, Lila & Rosalind Klaas (1929) Journal of the American Chemical Society, 51: 3441–3446. “The Composition of Cholla Gum. I. The Isolation of l-Arabinose, d-Galactose and l-Rhamnose.”

Sanguin 1829 in the literature refers to Sahagún 1829.

Santi-Soncin, E. & M. Furlenut (1972) Fitoterapia,43: 21.

Sarkis, Alia & Víctor Campos (1991) Curanderismo Tradicionale del Costariccense. Curaciones con plantas medicinales y remedios caseros. Second Edition (first edition was 1985) Lehmann Editores: San José, Costa Rica. ISBN 9977-949-23-9. 188 pages.

Saskai, Y. et al. (2009) Biological & Pharmaceutical Bulletin, 32 (5): 887–891. “Rapid and Sensitive Detection of Lophophora Williamsii by Loop-Mediated Isothermal Amplification” (Yohei Sasaki, Tsuguto Fujimoto, Masako Aragane, Ichiro Yasuda & Seiji Nagumo)

Sato, M. et al. (1967) Jpn. J. Pharmacol. 17: 153–163. “Studies on tetrahydroisoquinolines. II. Pharmacological action on cardiovascular system.” (M. Sato, I. Yamaguchi & A. Kiyomoto)

Sato, P.T. et al. (1973) Journal of Pharmaceutical Sciences. 62 (3): 411–414. “Cactus Alkaloids. XVI. Isolation and identification of alkaloids in Coryphantha ramillosa” (P.T. Sato, J.M. Neal, L.R. Brady & J.L. McLaughlin)

Sato, Tony (1996) Cactus Handbook. Japan Cactus Planning Company, Fukushima, Japan.

Sava, V. (1929) Thèse doctorale de Médicine, Bucharest.
“Recherche sur l’audition colorée et l’intoxication
expérimentale par la mescaline.”

Sawyer, Alan R. (1975) Ancient Peruvian Ceramics. From the
Kehl and Nena Markley Collection. Museum of Art,
Pennsylvania State University Publication.

Sax, N. Irving (1984) Dangerous Properties of Industrial
Materials
. Sixth Edition. Page 1757.

Sax, N. Irving & Richard J. Lewis, Sr. (1989) Dangerous Properties of Industrial Materials. 7th edition. 3 volumes. Van Nostrand Reinhold. ISBN 0-442-28020-3 (set). Entries MDI500 (mescaline as base), MDI750 (as hydrochloride) and MDJ000 (as sulfate)

Saxena, A. et al. (1962) Archives Internationales de Pharmacodynamie et de Thérapie, 140: 327–335. “Behavioural studies in fish with mescaline, LSD, and thiopropazate and their interactions with serotonin and dopa.” (A. Saxena, B K. Bhattacharya & B. Mukerji)

Schaafsma, Polly (1980) Indian Rock Art of the Southwest. University of New Mexico Press: Albuquerque.

Schaefer, Stacy (1989) Journal of Latin American Lore, 15 (2): 179–194. “The Loom and Time in the Huichol World.”

Schaefer, Stacy (1993)a “The Loom as a Sacred Power Object in Huichol Culture.” pp. 118–130 in R. Anderson & K. Field (eds.) Art in Small Scale Societies. Prentice Hall: New York.

Schaefer, Stacy (1993)b Latin American Art, Spring 93: 70–73. “Huichol Indian Costumes: A Transforming Tradition.”

Schaefer, Stacy (1995) Integration, 5: 35–49. “The Crossing of the Souls: Peyote, Perception and Meaning Among the Huichol Indians of Mexico.”

Schaefer, Stacy (1997) Jahrbuch für Ethnomedizin und Bewußtseinforschung, 5 (1996) “Peyote and Pregnancy.”

Schaefer, Stacy (1998)a Becoming a Weaver: The Woman’s Path in Huichol Culture. University of Utah Press.

Schaefer, Stacy (1998)b “Dove le anime si incontrano. La percezione huichol del peyote.” pp. 57–77 in Giovani Feo (ed.) Sciamani delle due Americhe. Stampa Alternativa: Rome

Schaefer, Stacy (1998)c Altrove 5: 43–48. “Quando si incontrano le anime. L’importanza del peyote nella cultura Huichol.”

Schaefer, Stacy & Furst, Peter (eds.) (1996) People of the Peyote: Huichol Indian History, Religion, and Survival. University of New Mexico Press: Albuquerque. ISBN 0-8263-1684-0. 608 pages.

Schäfer, George & Cuz, Nan (1968) In Reiche des Mescal. Synthesis Verlag: Essen.

Schelle, Ernst (1926) Kakteen. Tübingen: A. Fischer Vlg.
page 150 “Reihe: Macrogonus, groβrippige.” Figure 19. “Cereus macrogonus Salm-Dyck.” [Great image but sadly preserving Glaziou’s mistaken guess as to its origin.]

Schenker, F. et al. (1971) Journal of Heterocyclic Chemistry, 8: 665–668. “Monophenolic 1,2,3,4-tetrahydroisoquinolines and their methyl ethers.” (F. Schenker, R.A. Schmidt, T. Williams & A. Brossi)

Schepetkin, I.A. et al. (2008) International Immunopharmacology, 8: 1455–1466. “Macrophage immunomodulatory activity of polysaccharides isolated from Opuntia polyacantha.” (Igor A. Schepetkin, Gang Xie, Liliya N. Kirpotina, Robyn A. Klein, Mark A. Jutila & Mark T. Quinn)

Schlumberger, Boris O. & Susanne S. Renner (2012) American Journal of Botany, 99(8): 1335–1349. “Molecular phylogenetics of Echinopsis (Cactaceae). Polyphyly at all levels and convergent evolution of pollinaton modes and growth forms.”

Schlumpberger, B.O. et al. (2004) International Journal of Plant Science, 165 (6): 1007–1015. “Musty-Earthy Scent in Cactus Flowers: Characterization of Floral Scent Production in Dehydrogeosmin-Producing Cacti.” (Boris O. Schlumpberger, Andreas Jux, Maritta Kunert, Wilhelm Boland & Dieter Wittmann)

Schlumpberger, B.O. et al. (2006) Plant Biology (Stuttgart), 8 (2): 265–270. “A unique cactus with scented and possibly bat-dispersed fruits: Rhipsalis juengeri.” (B. O. Schlumpberger, R. A. Clery & W. Barthlott)

Schmidt, Paul (1969) Journal of the Cactus and Succulent Society of America, 4 (6): 265. “Hybridization of Lophophora Williamsii with Turbinicarpus and Mammillaria.”

Schneck, Marcus (1992) Cacti. An Illustrated Guide to over 150 Representative Species. Crescent Books: New York/Avenel, New Jersey. ISBN 0-517-07321-8.

Schneider, Woldemar & Bertold Müller (1958) Justus Liebigs Annalen der Chemie, 615 (1) 34–42. “Beiträge zur Chemie der Carbinolamine. I Untersuchungen an Py-Tetrahydroisochinolinen.”

Schnoll, S.H. et al. (1972) Journal of Psychedelic Drugs, 5 (1): 75–78. “A Rapid Thin Layer Chromatographic Screening Procedure for Various Abused Psychotropic Agents.” (Sidney H. Schnoll, Richard D. Cohen & Wolfgang H. Vogel)

Schöpf, C. & H. Bayerle (1934) Annalen der Chemie, 513: 190–202. “Zur frage der biogenese der isochinolin-alkaloide. Die synthese des 1-methyl-6,7-dioxy-1,2,3,4-tetrahydroisochindins inter physiologisschen bedinigemgen.”

Schueler, F.W. (1948) Journal of Laboratory and Clinical Medicine, 33: 1297–1303. “The effect of succinate in mescaline hallucinations.”

Schultes, Richard Evans (1936) Thesis, Harvard University. “Peyote Intoxication, A Review of the Literature on the Chemistry, Physiology and Psychological Effects of Peyotl.”

Schultes, Richard Evans (1937)a Botanical Museum Leaflets. Harvard University, 4 (8): 129–152. “Peyote and Plants Used in the Peyote Ceremony.”

Schultes, Richard Evans (1937)b Botanical Museum Leaflets. Harvard University, 5 (5): 61–88. “Peyote (Lophophora Williamsii) and Plants Confused With It.”

Schultes, Richard Evans (1938) American Anthropologist, N.S. 40: 698–715. “The Appeal of Peyote (Lophophora Williamsii)as a Medicine.”

Schultes, Richard Evans (1939) Harvard University, Botanical Museum Leaflets, 7 (3): 37–54. “Plantae Mexicanae II. The Identification of Teonanacatl, a Narcotic Basidiomycete of the Aztecs.”

Schultes, Richard Evans (1940) Journal of the Cactus and Succulent Society of America, 12 (11): 177–181. “The Aboriginal Therapeutic Uses of Lophophora Williamsii.”

Schultes, Richard Evans (1967) “The Place of Ethnobotany in the Ethnopharmacological Search for Psychotomimetic Drugs.” pp. 33–57 in: Ethnopharmacological Search For Psychoactive Drugs. United States Government Printing Office, Publication #1645.

Schultes, Richard Evans (1969) Botanical Museum Leaflets. Harvard University, 22 (4): 133–164. “De plantis toxicariis e mundo novo tropicale commentationes. IV.” (Page 142)

Schultes, Richard Evans (1969) Science, 163: 245–254. “Hallucinogens of Plant Origin.”

Schultes, Richard Evans (1972) “An Overview of Hallucinogens in the Western Hemisphere.” pp. 3–54 in Furst (ed.) 1972

Schultes, Richard Evans (1972)a Botanical Museum Leaflets. Harvard University, 23 (3): 137–147. “De Plantis Toxicariis e Mundo Novo Tropicale Commentationes X. New Data on the Malpighiaceous Narcotics of South America.” [Epiphyllum]

Schultes, Richard Evans (1972)c Plant Science Bulletin, 18 (4): 34–40. “De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XI. The Ethnotoxicological Significance of Additives to New World Hallucinogens.” [Epiphyllum]

Schultes, Richard Evans (1998) The Heffter Review of Psychedelic Research, 1: 1–7. “Antiquities of the New World Hallucinogens.”

Schultes, Richard Evans & Albert Hofmann (1980) Botany and Chemistry of the Hallucinogens. Second Edition. Charles C. Thomas, Springfield, Illinois. ISBN # 0-398-03863-5.[ Paperback ISBN 0-398-06416-4] 462 pages.[See also as Schultes & Hofmann (1983) Botanica e chimica degli allucinogeni. Roma (Cesco Ciapanna)]

Schultes, Richard Evans & Albert Hofmann (1992) Plants of the Gods. Origins of Hallucinogenic Use. Healing Arts Press. [Also (1979) Plants of the Gods. Origins of Hallucinogenic Use. Alfred Van Der Marck Editions 1979. Originally published by McGraw-Hill: New York 1979 [See also as (1993) Les Plantes des Dieux. Les Éditions du Lézard. 232 pp. ISBN 2-910718-02-6 & ISBN 2-9507264-2-9 or as (1993) Plantas de los Dioses. Fondo de Cultura Económica. 192 pp. ISBN 968-16-1023-7; or as (1995) Pflanzen der Götter. AT Verlag. 191 pp. ISBN 3-85502-543-6.]

Schultes, Richard Evans & Robert F. Raffauf (1990) The Healing Forest: Medicinal and Toxic Plants of the Northwest Amazonia. Dioscorides Press.

Schumann, K. (1894) Monatsschrift für Kakteenkunde 4: 36–37. “Echinocactus Williamsii Lem.”

Schumann, K. (1895) Monatsschrift für Kakteenkunde 5: 11–15. “Kleine Mitteilungen und Fingerzeige.”

Schumann, Karl Moritz (1895) Berichte der Deutschen
Pharmazeutischen Gesellschaft
, 103–110. “Über giftige Kakteen.”

Schumann, Karl Moritz (1897) Gesamtbeschreibung der Kakteen, 81 [Cereus tephracanthus bolivianus Weber] [From Britton & Rose; Ritter gives as 1898] See as Schumann 1899.

Schumann, Karl Moritz (1897) Gesamtb. Kakteen 108 [Cereus bridgesii brevispinus & Cereus bridgesii lageniformis] [From Britton & Rose] See as Schumann 1899

Schumann, Karl Moritz (1898) Botanische Jahrbücher für Systematik, Pflanzengeschichte, und Pflanzengeographie. 24: 541–567. “Die Gattung Ariocarpus (Anhalonium).” (see page 551)

Schumann, Karl Moritz (1897) Gesamtbeschreibung der Kakteen (Monographia Cactearum) 80–81. “25. Cereus tephracanthus Lab.” Comments on Cereus tephracanthus var. boliviana Weber are on page 81. [Britton & Rose cites this as a reference for Cereus tephracanthus bolivianus Weber]

Schumann, Karl Moritz (1897) Gesamtbeschreibung der Kakteen (Monographia Cactearum) 107–108. “52. Cereus bridgesii S.-D.” [First apearance of Cereus bridgesii brevispinus Schumann & Cereus bridgesii lageniformis Schumann. In this paper, Schumann also noted his belief that the former is identical with C. macrogonus.]

Schumann, Karl Moritz (1898) Botanische Jahrbücher für Systematik, Pflanzengeschichte, und Pflanzengeographie. 24: 541–567. “Die Gattung Ariocarpus (Anhalonium).” (see page 551)

Schumann, Karl Moritz (1899) Gesamtbechreibung der Kakteen, 

   80–81: “25. Cereus tephracanthus.”,

 115–116: “XVI Reihe Macrogoni (Groβrippige K. Sch. 59 Cereus macrogonus S.-D.” [In this work Schumann patches the discrepancies appearing in Flora Brasiliensis, notes the correction of the homeland proposal (of Glaziou) that was brought to his attention by Weber, added correct floral elements and commented on his belief that macrogonus was synonymous with bridgesii brevispinus.]

Schumann, Karl Moritz (1902) Monatsschrift für Kakteenkunde 12 (2): 19–23. “Succulente Reiseerinerungen.” [Given as a reference for the name Cereus bolivianus Weber which is only mentioned in passing on page 21.]

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Schwartz & Scott (1971) J Org Chem 36: 1827? 

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Shamma, M. & H.R. Rodriguez (1965) Tetrahedron Letters, 4347 (from Jeffs et al. 1969)

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Sharon, Douglas C. (1978) Wizard of the Four Winds: A Shaman’s story. The Free Press, Collier MacMillan Publishers, New York.

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Sharon, Douglas C. (1986) Comments made in a taped workshop entitled “Mind, Molecules and Magic” as quoted in 1995 Entheogen Review 4 (1): 13. “T. peruvianus toxicity?”

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Shulgin, Alexander T. (1973) Lloydia, 36 (1): 46–58. “Mescaline: The Chemistry and Pharmacology of its Analogs.”

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Shulgin, Alexander T. (1977) Journal of Psychedelic Drugs, 9 (2): 171–172. “Profiles of Psychedelic Drugs: STP.”

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Shulgin, Alexander T. (nd) Information from e-mail forwarded by MS Smith; dated 8 August 1999

Shulgin, Alexander T. & Ann Shulgin (1991) PIHKAL: A Chemical Love Story. Transform Press 978 pages ISBN 0-9630096-0-5.

Shulgin, Alexander T. & Ann Shulgin (1997) TIHKAL: The Continuation. Transform Press 804 pages ISBN 0-9630096-9-9.

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Sicé, J. (1962) General Pharmacology. W.B. Saunders Co., Philadelphia.

Siegel & Jarvik (1975) pp 81–162 in Siegel & West (eds.) See also Horowitz p. 178.

Siegel, M. & H. Tefft (1971) J. Nerv. Ment. Dis. 152: 412

Siegel, Ronald K. (1971) “Studies of hallucinogens in fish, brids, mice and men: The behavior of “psychedelic” populations” pp. 311–318 in O. Vinar, Z. Voltava & P.B. Bradley (eds) Advances in Neuro-Psychopharmacology. Amsterdam: North Holland

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Siegel, Ronald K. & Louis Jolyon West (eds) (1975) Hallucinations: Behavior, Experience and Theory. Wiley: New York.

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Siméon, Rémi (1885) Dictionnaire de la langue Nahuatl ou Mexicaine, p. 436. Paris.

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Singer & Elbe (1980) J. Food Sci. 45: 489

Singer et al. 1980 in the literature meant Singer & Elbe 1980

Singh et al. (1978) J. Heterocyclic Chem, 15: 541

Siniscalco et al. 1983 (in the literature) meant Siniscalco 1983

Siniscalco Gigliano, G. (1983) Bolletino Chimico Farmaceutico, 122: 499–504. “La Mescalina in Lophophora Coult. Ed in Altre Cactaceae.”

SISSC (1994) Bibliografia Italiana su Allucinogenie Cannabis, (Società Italiana per lo Studio degli Stati di Cosienza c/o Museo Civico di Roverto) Edizioni Grafton 9, Bologna. [Contributors: Carlo Buono, Gilberto Camilla, Gino Dal Soler, Francesco Festi, Fulvio Gosso, Mario Lorenzetti & Giorgio Samorini.]

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Sivadjian, Joseph (1969) Comptes Rendus Hebdomaries des Séances de L’Académie des Sciences, Série D. [AKA C.R. Acad. Sc. Paris. Série D.] 268 (6): 984–985. “L’action de la mescaline et du diéthylamide de l’acide lysergique (LSD-25) sur le comportement du Cobaye.”

Sjoberg, B.M. Jr. & L.E. Hollister (1962) Psychopharmacologia, 3: 219–223. (in the literature) meant Wolbach et al. 1962

Sjoberg, B.M. Jr. & L.E. Hollister (1965) Psychopharmacologia, 8 (4): 251–262. “The Effects of Psychotomimetic Drugs on Primary Suggestibility.”

Sjöquist & Magnusen (1980) J. Chromatogr., 183: 17–24

Sjöquist et al. (1981a) Subst. Alc. Actions/Misuse, 2: 63–72.

Sjöquist et al. (1981b) Subst. Alc. Actions/Misuse, 2: 73–77.

Sjöquist et al. (1981c) Eight Internat. Congr. Pharmacol., July 19–24, Tokyo. Abstract page 398.

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Sjöquist, B. et al. (1983) Drug and Alcohol Dependence, 12: 15–23. “The effect of alcoholism on salsolinol and biogenic amines in human brain.” (Birgitta Sjoquist, Eva Perdahl & Bengt Winblad)

Skarin, Annalee (1966) (1981 – 7th printing) Man Triumphant. DeVorse & Co.: Marina Del Rey. ISBN 0-87156-091-3. 253 pages.

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Slotkin 1954 in the literature meant Slotkin 1955. [Slotkin 1954 is Saturday Review, 37: 14. “Mescalin: A substitute for tobacco? III The anthropologist.”]

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Slotkin, James S. (1952) Transactions of the American Philosophical Society, 42 (pt. 4): 565–700. “Menomimi Peyotism. A study of individual variation in a primary group with a homogenous culture.” [pp. 681–700 is David P. McAllester’s “Menomini peyote music.”]

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Slotkin, James S. (1956) The Peyote Religion: A Study in Indian-White Relations. The Free Press: Glencoe

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Slotta, K.H. & W. Altner (1931) Berichte der Deutschen Chemischen Gesellschaft, 64: 1510–1520. “Über β-Phenyl-äthylamine. II. Eine neue Tyramin-Synthese.”

Slotta, K.H. & H. Heller (1930) Berichte der Deutschen Chemischen Gesellschaft, 63: 3029–3044. “Über β-phenyl-äthylamine. I. Mitteil. Mezcalin und mezcalin-ähnlicher Substanzen.”

Slotta, K.H. & G. Szyska (1933) Journal fuer Praktische Chemie, 137: 339–350. “Über β-Phenyl-äthylamine. III. Eine neue Mezcalin-Synthese.” [This is an electrochemical reduction of nitrostyrene!]

Slotta, K.H. & G. Szyzka (1934) Berichte der Deutschen Chemischen Gesellschaft, 67: 1106–1108. “Synthese des mescalins. (Eine Berichtigung der gleichlautenden Arbeit von G. Hahn und H. Wassmuth.)”

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Slotta, K.H. et al. (1937) Mem. Inst. Butantan (São Paulo), 11: 101. (K.H. Slotta, J.C. Valle & K. Neisser) [From Deulofeu & Ruveda 1971]

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Smith et al. (1972) J. Chem Soc. Perkins Trans. 1: 228

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Smith, Maurice G. (1929) Oklahoma Daily, December 8. “Peyote”

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Smith, Michael S. (2000) Narcotic & Hallucinogenic Cacti of the New World. [TN#C-14] Better Days Publishing. (Also distributed as privately printed manuscript) M.S. Smith has our thanks for bringing the work of Dr. Štarha to our attention. Now retitled Sacramental and Medicinal Cacti – available online: http://www.cactus-mall.com/mss/

Smith, Michael S. (2006) Personal communications.

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Smith, Mrs. Maurice G. 1934 See as Elna Smith 1934

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Smith, Terence A. (1977)a Phytochemistry, 16: 9–18. “Phenethylamine and related compounds in plants.”

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Smithsonian (date?) Traditional Music of Peru 5. Celebrating divinity in the high andes. CD Smithsonian Folkways Recordings.

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Smolenski, S.J. et al.(1973) Lloydia, 36 (4): 359–389. [S.J. Smolenski, H. Silinis & N.R. Farnsworth] “Alkaloid Screening. III.”

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Smythies, J.R. (1963) British Journal of the Philosophy of Science 3: 339–347. “The mescaline phenomenon.”

Smythies, J.R. & C.K. Levy (1960) Journal of Mental Science, 106: 531–536. “The comparative psychopharmacology of some mescaline analogs”

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Smythies, J.R. & E.A. Sykes (1965) Fed. Proc. 24: 196.

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Smythies, J.R. et al. (1969) British Journal of Psychiatry, 116: 55–68. “Behavioral models of psychosis “ (J.R. Smythies, V.S. Johnston & R.J. Bradley)

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Snow, Otto (1998) Amphetamine Syntheses. Overview & reference guide for professionals. (Psychoactive Synthesis Series Volume 1) Thoth Press; Spring Hill FL. ISBN #0-9663128-0-5.

Snyckers, F.O. et al. (1971) Journal of the Chemical Society, D. Chemical Communications, 1467–1469. “The Structures of Partially Racemic Sceletium Alkaloid A4 and Tortuosamine, Pyridine Alkaloids from Sceletium tortuosum.” (F.O. Snyckers, F. Strelow & A. Wiechers)

Snyder, Solomon & Carl R. Merril (1965) Procedings of the National Academy of Sciences of the United States of America 54: 258–266. “A relationship between the hallucinogenic activity of drugs and their electronic configuration”

Soc. Anon. pour L’Ind. Chim. a Bâle (1930)a British Patent 360,266, Jan. 8, 1930; [CA (1933) 27: 513.] [CA says patent was for 3,4,5-Triethoxyphenethylamine.]

Soc. Anon. pour L’Ind. à Bâle (1930)b Swiss Patent 147,949 Jan. 8 1930. [CA (1932) 26: 2278] “3,4,5-Triethoxyphenethylamine”

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Soeda, M. (1969) Journal of the Medical Society of Toho University 16: 365–369. “Studies on the anti-tumor activity of Cape Aloe.”

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Solomon, K. (in the literature) meant Salomon, K.

Soskin, Samuel & Matthew Tabenhaus (1943) Journal of Pharmacology and Experimental Therapeutics, 78: 49. “Sodium succinate as an antidote for barbiturate poisoning and in the control of the duration of barbiturate anethesia. (Including its successful use in a case of barbiturate poisoning in a human.)”

Soulaire, Jacques (1947) Cactus et Médecine. Éditions Thiébaut Paris. (PhD thesis) 186 pages.

Sourkes, Theodore L. (1958) Revue Canadienne de Biologie, 17 (3): 328–366. “Oxidative Pathways in the Metabolism of Biogenic Amines.”

Southon, Ian W. & John Buckingham (1989) Dictionary of Alkaloids. Chapman and Hall, London and New York. Two volumes. ISBN # 0-412-24910-3. (G.A. Cordell, J.E. Saxton, M. Shamma and G.F. Smith, ed. board)

Späth, Ernst (1919) Monatshefte für Chemie, 40: 129–154, “Über die Anhalonium-Alkaloide.”

Späth, Ernst (1920) Anzeiger der Kaiserlichen Akademie der Wissenschaften, 57 (12): 135–136. “Die Synthese des Sinapines.”

Späth, Ernst (1921)a Monatshefte für Chemie, 42: 97–115. “Über die Anhalonium-Alkaloide. II. Die Konstitution des Pellotins, des Anhalonidins, und des Anhalamins” CHECK AND insert ALL A or b CORRECTLY

Späth, Ernst (1921)b Monatshefte für Chemie, 42: 263–266. “Über die Anhalonium-Alkaloide III. Konstitution des Anhalins.” [Hordenine]

Späth, Ernst (1922) Monatshefte für Chemie, 43: 477–484. “Über die Anhaloniumalkaloide. V. Die Synthese des Anhalonidins und des Pellotins.”

Späth, Ernst (1929) Berichte der Deutschen Chemischen Gesellschaft, 62 (4): 1021–1024. “Über das Carnegin”

Späth, Ernst (1932) Berichte der Deutschen Chemischen Gesellschaft, 65 (10): 1778–1785. “Über die Konstitution von Pellotin und Anhalonidin”

Späth, Ernst & Friedrich Becke (1934)a Berichte der Deutschen Chemischen Gesellschaft, 67 (2): 266–268. “Eine neue Synthese des Pellotins (XI. Mitteil. über Kakteen-Alkaloide.)”

Späth, Ernst & Friedrich Becke (1934)b Berichte der Deutschen Chemischen Gesellschaft, 67 (12): 2100–2102. “Die Konstitution des Anhalamins. (XII. Mitteilung über Kakteen-Alkaloide.)”

Späth, Ernst & Friedrich Becke (1935)a Berichte der Deutschen Chemischen Gesellschaft, 68 (3): 501–505. “Über ein neues Kakteen-Alkaloid, das Anhalinin, und zur Konstitution des Anhalonins (XIII. Mitteil. über Kakteen Alkaloide.)” [0.096 grams of Anhalinine from 1330 grams of peyote.]

Späth, Ernst & Friedrich Becke (1935)b Berichte der Deutschen Chemischen Gesellschaft, 68 (5): 944–945. “Über des Anhalidin (XIV. Mitteil. über Kakteen-Alkaloide.)” [Synthesis of Anhalidine; From peyote: Anhalamine 0.1%; Anhalinine 0.01%; Anhalidine 0.001%]

Späth, Ernst & Friedrich Becke (1935)c Monatshefte für Chemie, 66: 327–366. “Über die tiennung der Anhalonium basen (Kakteen alkaloide. XV.)”

Späth, Ernst & Friedrich Boschan (1933) Monatshefte für Chemie, 63: 141–153.”Über Kakteenalkaloide. X. Die Konstitution des Pellotins un des Anhalonidins.”

Späth, Ernst & Johann Bruck (1937) Berichte der Deutschen Chemischen Gesellschaft, 70 (12): 2446–2450. “Über ein neues alkaloid aus den Mezcal buttons. (XVIII Mitteil. über Kakteen-Alkaloide.)” [N-Methylmescaline.]

Späth, Ernst & Johann Bruck (1938) Berichte der Deutschen Chemischen Gesellschaft, 71 (6): 1275–1276. “N-Acetyl mezcalin als Inhaltstoff der Mezcalin-Buttons (XIX. Mitteil. über Kakteen-Alkaloide.)”

Späth, Ernst & Johann Bruck (1939) Berichte der Deutschen Chemischen Gesellschaft, 72 (2): 334–338. “Über das O-Methyl-d-anhalonidin (XX. Mitteil. über Kakteen-Alkaloide.)”

Späth, Ernst & Ferdinand Dengel (1938) Berichte der Deutschen Chemischen Gesellschaft, 71 (1): 113–119. “Synthese des Salsolidins.”

Späth, Ernst & Joef Gangl (1923) Monatshefte für Chemie, 44: 103–113. “Über die Anhaloniumalkaloide. VI, Anhalonin und Lophophorin”

Späth, Ernst & Rudolf Göhring (1920) Anzeiger der Kaiserlichen
Akademie der Wissenschaften
, 57 (12): 136. “Die Synthesen des Ephedrins, des Pseudoephedrins, ihrer optischen Antipoden
und Razemkörper.”

Spath, Ernst & Percy Lavon Julian (1931) Ber. 64: 1131

Späth, Ernst & F. Kuffner (1929) Berichte der Deutschen
Chemischen Gesellschaft
, 62 (8): 2242–2243. “Die identitat des Pectinins mit dem Carnegin.”

Späth, Ernst & Friederike Kesztler (1935) Berichte der Deutschen Chemischen Gesellschaft, 68 (9): 1663–1667. “Synthese des Anhalonidins und des Lophophorins (XVI. Mitteil. über Kakteen-Alkaloide)”

Späth, Ernst & Friederike Kesztler (1936) Berichte der Deutschen Chemischen Gesellschaft, 69 (4): 755–757. “Über die optische Aktivität des Pellotins (XVII. Mitteil. über Kakteen-Alkaloide)”

Späth & Passl 1932 in the literature should read Späth 1932.

Späth, Ernst & Nikolaus Polgar 1929 Monatshefte für Chemie 51: 190-204. “Über eine Synthese von nichthydrierten Isochinolinabkömmlingen.”

Späth, Ernst & Hans Roder (1922) Monatshefte für Chemie, 43: 93–111.”Über die Anhalonium-Alkaloide. IV. Die Synthese des Anhalamins.”

Späth, Ernst & Philipp Sobel (1920) Monatshefte für Chemie, 41 (1): 6. “Uber neue Synthesen des Hordenins.”

Späth, Ernst & Philipp Sobel (1920) Monatshefte für Chemie, 41 (2): 77–90. “Neue Synthesen des Hordenins.” [New procedures for the synthesis of hordenine are described.]

Späth et al. 1932 Ber. 65: 1778 in the literature refers to Späth 1932.

Späth et al. 1934 Ber. 67: 266 in the literature refers to Späth & Becke 1934a

Späth, E. et al. (1934) Berichte der Deutschen Chemischen Gesellschaft, 67 (7): 1214–1217. “Konstitution und Synthese des Salsolins.” (Ernst Späth, Alexander Orechoff & Friedrich Kuffner)

Späth et al. 1935 (in the literature) See as Spath & Becke 1935a

Späth et al. 1936 (in the literature) See as Spath & Kesztler 1936

Speck, Louise B. (1957) Journal of Pharmacology and Experimental Therapeutics, 119: 78–84. “Toxicity and Effects of Increasing Doses of Mescaline.”

Spector, Elliot (1961) Nature, 189 (4766): 751–752. “Identification
of 3,4,5-trimethoxyphenylacetic acid as the major metabolite of mescaline in the dog.”

Spegazzini, Carlo (1905) Anales del Museo Nacional de Buenos Aires, 3 (4): 480. “11. Cereus thelegonoides Spegazzini. (n. sp.) “

Speir, W.W. et al. (1970) Lloydia, 33 (1): 15–18. “Cactus alkaloids. VII. Isolation of hordenine and N-methyl-3,4-dimethoxy-β-phenethylamine from Ariocarpus trigonus” (W.W. Speir, V. Mihranian & J.L. McLaughlin)

Spencer, G.F. et al. (1983) Journal of Natural Products, 46: 551–558. “The Triterpene Esters of Dolichothele longimamma (Cactaceae).” (G.F. Spencer, K. Payne-Wahl, R.B. Wolf & J.L. McLaughlin)

Spiegel, H.E. & R.P. Christian (1971) Clin. Chim. Acta, 31: 143.

Spinella, Marcello (2001) The Psychopharmacology of Herbal Medicine. MIT Press. 578 pages. ISBN 0-262-69265-1.

Spix & Martius (1831) Reise in Brasilien, 3: 1075 (From Safford 1916)

Sri Nurestri, AM et al. (2008) International Journal of Cancer Research, 4: 20–27. “Cytotoxic activity of Pereskia bleo (Cactaceae) against selected human cell lines.” (AM Sri Nurestri, AW Norhanom, Y Hashim, KS Sim, SL Hong & GS Lee) [from Sim et al. 2010]

Sri Nurestri, A.M. et al. (2009) Journal of Biological Sciences, 9: 488–493. “Phytochemical and cytotoxic investigations of Pereskia grandifolia Haw. (Cactaceae) leaves.” (A.M. Sri Nurestri, K.S. Sim & A.W. Norhanom) [from Sim et al. 2010]

Srivastava, B.K. & C.S. Pande (1974) Planta Medica, 25: 92–97. “Arabinogalactan From the Pods of Opuntia dillenii.”

Stafford, Peter (1992) Psychedelics Encyclopedia. Third Edition. Ronin Publishing, Inc. [pp. 103–155 (Chapter Two): “Peyote, Mescaline & San Pedro.” ISBN 0-914171-51-8. 420 pages.

Stahl 1969 Analyst (in the literature) meant Genest & Hughes 1968 Analyst.

Standley, Paul. C. (1920–1926) Contributions from the United States National Herbarium, Volume 23. “Trees and Shrubs of Mexico.”

Štarha 1994 (in the literature) sometimes actually means Štarha et al. 1994

Štarha, Roman (1994) Acta Facultatis Rerum Naturalium Universitas Ostraviensis, Physica-Chemia, 141 (2): 71–74. “Alkaloids of Three “Peyote” Cacti.”

Štarha, Roman (1995)a Chemica [Acta Universitatis Palackianae Olomucensis Facultas Rerum Naturalium] 34: 33–34. “Identification of Alkaloids of the Cactus Genus Gymnocalycium.

Štarha, Roman (1995)b Fitoterapia, 66 (4): 375. “Alkaloids of Epithelantha micromeris.

Štarha, Roman (1996)a Biochemical Systematics and Ecology, 24 (1): 85–86. “Alkaloids from the Cactus Genus Gymnocalycium.”

Štarha, Roman (1996)b Kaktusy, 32(2), 5. “Peyote”

Štarha, Roman (1997)a “Appendix IV. Chemický rozbor rodu Lophophora.” pp. 85–90 in Grym 1997.

Štarha, Roman (1997)b Kaktusy, 1: 11–13. “Psychoactive substances of plants of the genus Sceletium.” (A simple review of some of the chemistry.)

Štarha, Roman (1999) Cactaceae, 19 (4): 146–149. “Hybridni Turbinicarpusy.”

Štarha, Roman (2001)a Bioch. Syst. Ecol. (In Press) “Constituents of Gymnocalycium riojense Fric ex H.Till & W.Till (Cactaceae).” (from Štarha 2001c; See as Štarha 2002)

Štarha, Roman (2001)b Bioch. Syst. Ecol. (In Press) “Alkaloids of four varieties of Turbinicarpus schmiedickeanus (Bod.) Buxb. et Backeberg.” (from Štarha 2001c; this article has not been located so our account lacks further detail)

Štarha, Roman (2001)c Sekundární Metabolity Celedi Cactaceae. [Prací prírovedecké fakulty Ostravské Univerzity. Facultatis rerum naturalium Universitatis Ostraviensis. Spisy Scripta. Cislo 138] 108 pages.

Štarha, Roman (2002) Biochemical Systematics & Ecology, 30: 365–366. “Constituents of Gymnocalycium riojense Fric ex H.Till & W.Till (Cactaceae).”

Starha, Roman (n.d.) Cactus alkaloid summary. Undated (unpublished?) and privately distributed manuscript received from Dr. Starha in early 1999. [Previous versions also exist; received one around a year earlier via MSSmith]

Štarha, Roman (nd) Roman Štarha’s cactus alkaloid list. University of Ostrava, Czech Republic.

Štarha et al. 1994 (in the literature) meant Štarha 1994

Štarha, Roman & Jaroslav Kuchyna (1996) Acta Facultatis Rerum Naturalium Universtitas Ostraviensis, Physica-Chemia, 156 (3-4): 67–70. “Analysis of Mexican Populations of Lophophora (Cactaceae)”

Štarha, Roman et al. (1994) Acta Facultatis Rerum Naturalium Universtitas Ostraviensis, Physica-Chemia, 141 (2): 71–74. “Alkaloids of Three “Peyote” Cacti.”

Štarha, Roman et al. (1997) Biochemical Systematics and Ecology, 25 (4): 363–364. “Alkaloids from the Genus Gymnocalycium (Cactaceae) – II.” (Roman Štarha, Kamila Urbánková & Jaroslav Kuchyna)

Štarha, Roman et al. (1998) Acta Facultatis Rerum Naturalium Universtitas Ostraviensis, Physica-Chemia, 173 (6): 41–46. “Identifikace Alkaloidu V Rostlinách Rodu Gymnocalycium (Cactaceae) – III.” [Roman Štarha, Adéla Chybidziurová & Zdenek Lacný]

Štarha, Roman et al. (1999)a Acta Facultatis Rerum Naturalium Universitas Ostraviensis, 183 (7): 129–134. “The influence of hybridization to morphological nondependent properties of cacti.” (R. Štarha, Z. Hajnová & Z. Lacný)  (from Štarha 2001c; this article has not been obtained so our account lacks further detail)

Štarha, R. et al. (1999)b Acta Universitatis Palackinae Olomucensis Facultas Rerum Naturalium (Chemica). 38: 71–73. “Constituents of Turbinicarpus alonsoi Glass & Arias (Cactaceae).” (Roman Štarha, Adéla Chybidziurová & Zdenìk Lacný)

Štarha, Roman et al. (1999)c Biochemical Systematics & Ecology, 27: 839–841. “Alkaloids of the Genus Turbinicarpus (Cactaceae).” (Roman Štarha, Adéla Chybidziurová & Zdenek Lacný)

CHECK ALL A B AND C ARE ASSIGNED RIGHT

Štarha, Roman et al. (2000) Chem. Listy 94: 943–944. “Identifikace alkaloidu v rostlinách Turbinicarpus schmiedickeanus var. klinkerianus.” (R. Štarha, V. Smolka & Z. Lacný) (from Štarha 2001c; this article has not been obtained so our account lacks further detail)

My thanks also go to Dr. Starha for graciously providing the papers lacking sources in the US.

Steelink, C. et al. (1967) Phytochemistry, 6: 1435–1440. “Phenolic Constituents of Healthy and Wound Tissues in the Giant Cactus (Carnegiea gigantea).” (Cornelius Steelink, Margery Yeung & Roger L. Caldwell)

Steelink, C. et al. (1968) Phytochemistry, 7: 1673–1677. “Carbohydrate Constituents of Healthy and Wound Tissues in the Saguaro Cactus.” (Cornelius Steelink, Eve Riser & M.J. Onore)

Steensholt, Gunnar (1947) Acta Physiologica Scandinavica, 14: 356–362. “On an Amine Oxidase in Rabbit’s Liver.”

Steimetz, Paul (1990) Pipe, Bible and Peyote. Among the Oglala Lakota. University of Tennessee Press: Knoxville. ISBN 0-87-049-623-9. 250 pages.

Steinberg, Neil (1994) Rolling Stone, 5 May: 33–34. “The Law of Unintended Consequences: Mandatory minimum sentencing puts first-time offenders in jail for life and lets drug kingpins bargain for their freedom”

Steiner (1923) Compt. Rend. 176 (244) 1379

Steinigen, Manfred (1972) Deutsche Apotheker-Zeitung 112 (2): 51–55. “Nachweis und quantitative Bestimmung von Lysergsäurediäthylamid (LSD).”

Stern, et al. (1961) Archives Internationales de Pharmacodynamie et de Thérapie, 133: 58.

Steudel, E.G. v. (1840) Nomenclator Botanicus. Editio secunda. 1: 336. (AKA “Nom. Ed.”) (see also pages 334 & 335.)

Stevens, Jay (1987) Storming Heaven: LSD and the American Dream. Atlantic Monthly Press

Stevenson, Ian (1957)a Journal of Nervous and Mental Disease, 125 (3): 438–442. “Comments on the Psychological Effects of Mescaline and Allied Drugs.” (Part of “The Round Table: Annual Meeting of the American Psychiatric Association. Psychodynamic and Therapeutic Aspects of Mescaline and Lysergic Acid Diethylamide.” Herman C.B. Denber and Max Rinkel, editors, comprising pp. 423–452.)

Stevenson, Ian (1957)b New Republic, 136 (1): 22. “From Mescaline to Eternity.”

Stevenson, Ian & Andrew J. Sanchez (1957) American Journal of Psychiatry, 114 (4): 328–332. “The Antidotal Action of Sodium Succinate in the Mescaline Psychosis.”

Stevenson, Ian & Thomas W. Richards (1960) Psychopharmacologia, 1: 241–250. “Prolonged Reactions to Mescaline. A Report of Two Cases.”

Stewart, Omer C. (1944) Amer. Archaeol. and Ethnol. 40 (3): App. 2. “Washo-Northern Paiute Peyotism.”

Stewart, Omer C. (1956) Colorado Quarterly, 5: 79–90. “Peyote and Colorado’s Inquisition Law.”

Stewart, Omer C. (1980) Plains Anthropologist, 25 (90): 297–309. “Peyotism and Mescalism.”

Stewart, Omer C. (1984) (1993) Peyotism in the West: A Historical and Cultural Perspective. [Anthropological Papers: No. 108] 168 pp. University of Utah Press. ISBN 0-87480-235-0

Stewart, Omer C. (1987) Peyote Religion. [Civilization of the American Indian Series. Vol. 181] University of Oklahoma Press. ISBN 0-8061-2068-1 (hard)/ 0-8061-2457–1 (paper). 454 pages. Also (1993) University of Oklahoma Press. ISBN 0-8061-2457-1

Steyn, D.G. (1929) 15th Annual Report Division of Veterinary Services, 15: 777–803. “Recent Investigations Into the Toxicity of Known and Unknown Plants of the Union of South Africa.” (From Watt 1967)

Steyn, D.G. (1933) Onderstepoorte Journal of Veterinary Sciences and Animal Industry, 1: 173–182. “Recent Investigations Into the Toxicity of Known and Unknown Plants of the Union of South Africa.” (From Watt 1967)

Stintzing, F.C. et al. (1999) Planta Medica, 65: 632–635. “Amino Acid Composition and Betaxanthin Formation in Fruits from Opuntia ficus-indica.” (Florian C. Stintzing, Andreas Schieber & Reinhold Carle)

Stintzing, F.C. et al. (2002) Journal of Agricultural and Food Chemistry, 50 (8): 2302–2307. “Identification of betalains from yellow beet (Beta vulgaris L.) and cactus pear [Opuntia ficus-indica (L.) Mill.] by high-performance liquid chromatography-electrospray ionization mass spectrometry.” (Florian C. Stintzing, Andreas Schieber & Reinhold Carle)

Stintzing, F.C. et al. (2005) Journal of Agricultural and Food Chemistry, 53 (2): 442–451. “Color, Betalain Pattern, and Antioxidant Properties of Cactus Pear (Opuntia spp.) Clones.” (Florian C. Stintzing, Kirsten M. Herbach, Markus R. Mosshammer, Reinhold Carle, Weigung Yi, Subramani Sellappan, Casimir C. Akoh, Ron Bunch & Peter Felker)

Stjarne, L. (1966) Acta Physiology Scandinavica, 67: 441. Studies of noradrenaline biosynthesis in nerve tissue.“

Stockings, G.T. (1940) (in the literature)
See as Tayleur-Stockings 1940

Stone-Miller, Rebecca (1995) Art of the Andes: From Chavín to Inca. Thames and Hudson: London.

Straatman, Silke (1988) Die Wollbilder der Huichol-Indianer. Marburger Studien zür Völkerkunde Vol. 6: Marburg.

Strack, D. et al. (1987) Phytochemistry, 26: 2399–2400. “Neobetanin: A New Natural Plant Constituent.” (D. Strack, U. Engel & V. Wray )

Steinmetz, E.F. (1957) Codex Vegetabilis. Self-published, Amsterdam.

Strike (Hobart Huson) (1998) Total Synthesis II. Panda Press; San Antonio.

Stromböm, Jan & Jan G. Bruhn (1978)a Acta Pharmaceutica Suecica, 15 (2): 127–132. “Alkaloids of Pachycereus pecten-aboriginum, a Mexican cactus of ethnopharmacological interest”

Stromböm, Jan & Jan G. Bruhn (1978)b Journal of Chromatography, 147: 513–515. “High perfomance liquid chromatography of isomeric cactaceae alkaloids and related tetrahydroisoquinolines.”

Stromböm et al. (1980) Journal of Chromatography, 189: 79 

Strukov et al. 1959 Zh. Obshch. Khim. 29: 3831;

Strukov et al. 1961 Zh. Obshch. Khim. 31: 2709; [CA 54: 19676a; 56: 11567f] (synth, deriv)

Stuart, George E. (1992) National Geographic, 182 (3): 120–136. “Mural Masterpieces of Ancient Cacaxtla.” [Photographs by Enrico Ferorelli]

Stuart, R. (2002) Entheogen Review 11 (2): 58-61. “Tchai.”

Sturtevant, F.M. & Victor A. Drill (1956) Proceedings of the Society for Experimental Biology and Medicine, 92 (2): 383–387. (entry 22485) “Effects of mescaline in laboratory animals and influence of ataraxics on mescaline-response.”

Sultan, F.W. (1891) New York Medical Journal, 681.

Sunshine, Irving (ed.) (1981) CRC Handbook of Spectrophotometric Data of Drugs

Supniewski, J.V. (1930)a Polska Gazeta Lekarska, 9: 449–454, 737–740. “[Pharmacological properties of synthetic alkaloids of peyotl.”]

Supniewski, J.V. (1930)b Polska Gazeta Lekarska, 9: 287–293; (1931) 10: 961–964. “[Pharmacological properties of synthetic alkaloids of derived from mescaline.”]

Svenson, A. Baerheim and R. Verpoorte (1983) Chromatography of Alkaloids. Part A: thin-layer chromatography. Journal of Chromatography, Library- volume 23A. Elsevier, 1983. ISBN 0-444-42145-9 (VOL. 23A).

Suryanarayanan, T.S. et al. (2005) Mycological Research 109 (5):635–639. “Endophytic fungi associated with cacti in
Arizona.” (T.S. Suryanarayanan, S.K. Wittlinger & S.H. Faeth)

Swonger, Alvin K. & Larry L. Constantine (1983) Drugs and Therapy. A Handbook of Psychotropic Drugs. Second Edition. Little, Brown & Co., ISBN 0-316-82551-4.

SWGDrug [Scientific Working Group for the Analysis of Seized Drugs] (2005) Peyote & Mescaline, (revision: 27 June 2005). Available at: http://www.swgdrug.org/Monographs/PEYOTE.pdf

Syal, Rajeev (1996) Sunday Times (London) 28 January. “Raves in the Caves: Stone Age Britons Took Drugs.”

Szara, S. (1957) “Comparison of the psychotic effect of tryptamine derivatives with the effects of mescaline and LSD in self experiments.” pp. 460–463 in Garattini & Ghetti

Szasz, Thomas (1985) Ceremonial Chemistry: The Ritual Persecution of Drugs, Addicts and Pushers. (revised edition) Learnig Publications. ISBN 1-55691-019-3.

Szasz, Thomas (1992) Our Right to Drugs. The Case for a Free Market.

Szuman, Stefan (1930) Kwartalnik Psychologiczny, 1-2: 156–212. [Summary in German, pp. 214–220.] “Analiza formalina i psychologiczna widzeń meskalinowych.”

 

References: T through Z

References T-Z used for Sacred Cacti 4th edition.

This references list is still in progress and will continue to be modified during the editing process. If anything new has not been added yet and you need to know it now; drop me an email.

 

[Brackets around a title indicates it is an English translation of the actual title. ]

Incomplete citations or the use of the qualifier “From” usually indicates that the paper listed was a second-hand reference. This means that this work was unavailable to us and was the reference that was cited by our information source.

As a single listing

A through D

E through J

K through O

P through S

 

 

 

 

Takagi, S. et al. (1979) Shoyakugaku Zasshi, 33 (1): 35–37. “Isolation of Synephrine from Evodia Fruits.” (Text is in Japanese) (Shigekazu Takagi, Takeshi Kinoshita, Mieko Sameshima, Toshiyuki Akiyama, Shigeo Kobayashi and Ushio Sankawa)

Takahashi (in the literature) see as Kinoshita

Takahashi & Brossi 1982 Heterocycles, 19: 691

Takido, M. et al. (1970) Journal of Pharmaceutical Sciences, 59 (2): 271–273. “New synthesis of rac. Anhalonidine and rac. Pellotine” (M. Takido, K.L. Khanna & A.G. Paul)

Takizawa, T. et al. (1993) Journal of Natural Products, 56 (12): 2183–2185. “A New Type of Triterpene from Trichocereus pachanoi.” (Takaomi Takizawa, Kaoru Kinoshita, Kitotaka Koyama, Kunio Takahashi, Norio Kondo, Hiroshi Yuasa & Ken-Ichi Kawai)

Tampier, L. et al. (1977) Research Communications in Chemical Pathology and Pharmacology, 17: 731–734. “Influences of catecholamine-derivated alkaloids and β-adrenergic blocking agents on stereospecific binding of 3H-naloxone.” (L. Tampier, H.S. Alpers & V.E. Davis) ,

Tamuara, K. et al. (1974) Bull. Chem. Soc. Japan 47: 2682.

Tan, M.L. et al. (2005) Journal of Ethnopharmacology, 96: 287–294. “Methanolic extract of Pereskia bleo (Kunth) DC. (Cactaceae) induces apoptosis in breast carcinoma, T47-D cell line.” (M.L. Tan, S.F. Sulaiman, N. Najimuddin, M.R. Samian & T.S. Tengku Muhammad)

Tan, R.X. & W.X. Zou (2001) Nat. Prod. Rep., 18: 448–459. “Endophytes: a rich source of functional metabolites.” [from Wu et al. 2008]

Tani et al. (1978) YZ, 98: 1658.

Taniguchi, K. et al. (1964) J. Lab. Clin. Med. 64: 469. (K. Taniguchi Y. Kakimoto and M.D. Armstrong)

Tank, A. et al. (1976) Ann. NY Acad. Sci. 273: 219–226. “Ethanol induced alterations of dopamine metabolism in rat liver.” (A. Tank, H. Weiner and J.A. Thurman)

Tarsitano, F. (1945) Bolletino della società italiana di biologia sperimentale, 20: 762–763. “La ricerca tossicologica della mescalina.” [CA (1946) 40: 66646.] [“Toxicological studies on mescaline.”]

Tarsitano, F. (1947) Folia Medica, 30: 340–344

Tayleur-Stockings, G. (1940) Journal of Mental Science, 86: 29–47. “A clinical study of the mescaline psychosis with special reference to the mechanism of the genesis of schizophrenia and other psychotic states.”

Taylor, Walter R. (1956) Bulletin of the Texas Archeological Society, 27: 215–234. “Some Implications of the Carbon-14 dates from a cave in Coahuila, Mexico.”

Teirich, H. (1954) Psyche (Stuttgart) 7: 637–640. “Ueber eine Meskalinschädigung.”

Teitel et al. (1972) J. Med. Chem. 15: 845

Teitel et al. (1974) J. Med. Chem. 17: 134 (S.Teitel, J. O’Brien, W. Pool & A. Brossi)

Telang, Sadanand Anant (1973) Phytochemistry, 12: 2059. “2-Hydroxymethyl-4-Methoxy-α-Pyrone From Opuntia polyacantha.”

Teles, F. et al. (1984) Journal of the Science of Food & Agriculture, 35: 421–425.  “Amino and organic acids of prickly pear cactus (Opuntia ficus-indica L.).” (F. Teles, J. Stull, W. Brown & F. Whitting)

Tello, Julio César (1929) Antiguo Peru. Primera epoca. Lima

Tello, Julio César (1940) Primeros indicios de una cultura megalitica semjante a la de Chavin en la region central de Peru. Lima.

Tello, Julio César (1947) Paginas Escogidas. Universidad Nacional Mayor de San Marcos. Lima, Peru

Tello, Julio César (1960) Chavin. Cultura Matriz de la Civilización Andina. Primera Parte. Imprenta de la Universidad de San Marcos. Lima.

Terry, Martin Kilman (2005) PhD Dissertation; Texas A&M University. A Tale of Two Cacti: Studies in Astrophytum asterias and Lophophora Williamsii. 178 pages.

Terry, Martin (2007) “Button, button, who’s got the button? Commerce, Religion, Drug Regulation and Conservation in the Current Peyote Trade of the Texas Borderlands.” http://www.cactusconservation.org/CCI/bb1.html [A talk presented to the Center for Big Bend Studies, November 2007.]

Terry, Martin (2007) Cactus Conservation in the US-Mexico Borderlands: Case Studies. [http://www.cactusconservation.org/CCI/library/mt/2007_Terry_Cactus%20Conservation.pdf]

Terry, Martin (2009)b. Cactus & Succulent Society Journal, Volume 80. “Stalking the Wild Lophophora.”
4: 181–186. “Part 1 Chihuahua and Coahuila”
5: 222–228. Part 2 Zacatecas, San Luis Potosí, Nuevo León, and Tamaulipas”
6: 310–317. “Part 3 San Luis Potosí (central), Querétaro, and Mexico City”

Terry, Martin (2011) Phytologia, 93 (3): 330–340. “Regeneration of Lophophora Williamsii (Cactaceae) following mummification of its crown by natural freezing events, and some observations on multiple stem formation.“

Terry, Martin & James E. Mauseth (2006) Sida, 22 (1): 1565–592. “Root-shoot anatomy and post-harvest vegetative clonal development in Lophophora Williamsii (Cactaceae: Cacteae) Implications for conservation.”

Terry, Martin et al. (2006) Journal of Archaeological Science, 20: 1–5. “Lower Pecos and Coahuila peyote: new radiocarbon dates.” (Martin Terry, Karen L. Steelman, Tom Guilderson, Phil Dering & Marvin W. Rowe) [Interestingly, using his power as a peer reviewer for Nature, Juan Adovasio was able to thwart the first attempt to publish this paper which had corrected flaws in Adovasio’s work.]

Terry, Martin et al. (2011) Journal of the Botanical Research Institute of Texas, 5 (2): 661–675. “Limitations to natural production of Lophophora Williamsii (Cactaceae) I. Regrowth and survivorship two years post harvest in a South Texas population.” [Martin Terry, Keeper Trout, Bennie Williams, Teodoso Herrera & Norma Fowler]

Terry, M. et al. (2012) Journal of the Botanical Research Institute of Texas, 6 (2): 567–577. “Limitations to natural production of Lophophora Williamsii (Cactaceae) II. Effects of repeated harvesting at two-year intervals in a South Texas population.” (Martin K. Terry, Keeper Trout, Bennie Williams, Teodoso Herrera & Norma Fowler)

Tesoriere, L. (2005) Journal of Agricultural & Food Chemistry, 53 (20): 7851–7855. “Biothiols, taurine, and lipid-soluble antioxidants in the edible pulp of Sicilian cactus pear (Opuntia ficus-indica) fruits and changes of bioactive juice components upon industrial processing.” (Tesoriere L, Fazzari M, Allegra M, Livrea MA.) [from PubMed]

Texas Department of Public Safety. Peyote sales totals and distributors of Texas. Unpublished data available to the public on a walk-in basis.

Thale, T. et al. (1950) American Journal of Psychiatry, 106 (9): 686–691. “Hallucination and Imagery Induced by Mescaline.” (Interesting in spite of the fact they used psychiatric patients as guinea pigs.) (Thomas Thale, Beverly Wescott Gabrio and Kurt Salomon)

Thevet, André (1574) Histoire du Mexique.

Thompson, Charles Henry (1898) Annual Report of the Missouri. Botanical. Gardens, 9: 127–135. “The species of cacti commonly cultivated under the generic name Anhalonium.”

Thord-Gray, Ivor (1955) TARAHUMARA – ENGLISH ENGLISH – TARAHUMARA DICTIONARY, University of Miami Press, Coral Gables, Florida, 1170 pages with map.

Thuillier, J. (1956) Comptes Rendus des séances de la Société de Biologie et de ses filiales, 150: 1150–1151. “Suppression par la chlorpromazine des contractions utérines provoquées par la mescaline.”

Titelar, M. et al. (1988) Psychopharmacology 94(2): 213–216. “Radioligand binding evidence implicates the brain 5-HT2 receptor as a site of action for LSD and phenylisopropylamne hallucinogens.”

Tjio, J.H. et al. (1969) Journal of the American Medical Association, 210: 849. “LSD and chromosomes: A controlled experiment.” (Joe-Hin Tjio, Walter N. Pahnke & Albert A. Kurland) [Does not cause damage]

Tocher, R.D. (1972) Phytochemistry, 11: 1161

Todd, James S. (1969) Lloydia, 32 (3): 395–398. “Thin Layer Chromatographic analysis of Mexican populations of Lophophora (Cactaceae).”

Tomaso (1934) La Chimica, 10: 408

Tomina, L.D. et al. (1971) Izv. Akad. Nauk. SSSR, Ser. Khim. 10:2181. “Separation of racemic phenyl-α- and β-dialkylamino alcohols into optical isomers.” (L.D. Tomina, E.I. Klabunovskii, I. Yu, L.A. Kretova, N.L. Kholdyakov, T.A. Antonova and E.M. Cherkasova) [from Ranieri & McLaughlin 1977]

Tomita et al. (1963) Chem Pharm bull 11: 1477, 1484

Tomita et al. (1963) Tetrahedron Letters, 3: 127–130. “The Structure of Isopilocereine.” (M. Tomita, T. Kichuchi & K. Bessho)

Tomita, M & Y. Takano (1959) Yakugaku Zasshi, 79: 1331. From Patel 1968. [Unable to confirm. Our copies start with 1960.]

Tomita, M. & J. Kunitomo (1960) Yakugaku Zasshi, 80: 1300. [Also CA (1961) 55: 3641d.]

Tomko, J. et al. (1967) Lloydia, 30: 231.

Tonge, Sally R. & B.E. Leonard (1969) Life Sciences 8, part 1 (15): 805–814. “The Effects of Some Hallucinogenic Drugs Upon the Metabolism of 5-Hydroxy-Tryptamine in the Brain.”

Topchiev (1933) J. Appl. Chem., USSR 6: 529 [1934 CA 28: 2718]

Toro, Alfonso (1930) Proceedings of the Twenty-Third International Congress of Americanists (Held at New York, September 17–22, 1928) 101–121. “Las plantas sagradas de los Aztecas y su influencia sobre el arte precortesiano.”

Torres, Constantino Manuel (1996) Ann. Mus. civ. Roverto 11 (1995): 291–326. “Archaeological Evidence for the Antiquity of Psychoactive Plant Use in the Central Andes.”

Torres, Donna & Manuel Torres (1995) “San Pedro in the Pressure Pot.” pp. 283–284 in: Rätsch & Baker (eds.) Jahrbuch für Ethnomedizin und Bewußtseinsforschung. Issue #4.

Torres-Castillo J.A. et al. (2009) Phytochemistry, 70 (11–12): 1374–1381. “Characterization of a highly stable trypsin-like proteinase inhibitor from the seeds of Opuntia streptacantha (O. streptacantha Lemaire).” (J.A. Torres-Castillo, C. Mondragón Jacobo & A. Blanco-Labra) [from PubMed]

Towle, Margaret Ashley (1961) The Ethnobotany of Pre-Columbian Peru. [Viking Fund Publications in Anthropology No. 30. Aldine Publications, Chicago.]

Tranzer, J. P. & Thoenen, H. (1967) Experientia, 23: 743–745. “Electron microscopic localization of 5-hydroxydopamine (3,4,5-trihydroxy-phenyl-ethylamine), a new ”false” sympathetic transmitter.”

Trebach, Arnold S. (1987) The Great Drug War and Radical Proposals that Could Make America Safe Again. Macmillan Co.: New York.

Trejo-Gonzalez, A. et al. (1996) Journal of Ethnopharmacology, 55: 27–33. A purified extract from prickly pear cactus (Opuntia fulginosa) controls experimentally induced diabetes
in rats.” (A. Trejo-Gonzalez, G. Gabriel-Ortiz, A.M.
Puebla-Perez, M.D. Huizar-Contreras, M.R. Munguia-
Mazarigos & C.E. Mejia-Arreguins,)

Trout, K. (1998) Trout’s Notes on Tryptamines from Higher Plants. [TN# FS-X0] Better Days Publishing; Austin, TX.

Trout, K. (1999)a Trout’s Notes on Cactus Chemistry By Species. [TN#C-10a] Better Days Publishing; Austin, TX.

Trout, K. (1999)b Trout’s Notes on Sacred Cacti. Second Edition. [TN#SC2] Better Days Publishing; Austin, TX. [First edition 1997 by Narayan Publications; Sedona, AZ]]

Trout, Keeper & Burnt Norton (2010) Peyote in the Wilds of Texas. (http://www.erowid.org/plants/peyote/peyote_article4.shtml)

Trulson, M.E. et al. (1983) European Journal of Pharmacology, 96 (1-2): 151–154. “Mescaline elicits behavioral effects in cats by an action at both serotonin and dopamine receptors.” (M.E. Trulson, T. Crisp & L.J. Henderson)

Tsa Toke, Monroe (Huntinghorse) (1957) Visions and Descriptions of the Peyote Ritual. Grabhorn Press

Tsao, Makepeace U. (1951) Journal of the American Chemical Society, 73: 5495–5496. “A new synthesis of Mescaline.”

Tullar, J. (1948) Journal of the American Chemical Society, 70: 2067.

Turner, D.M. (1998) Comment made in correspondence during 1995 (Posthumously published: Entheogen Review 7 (1): 18.)

Turner, D.M. (Joseph Vivian) (1994) The Essential Psychedelics Guide. Panther Press; San Francisco. ISBN: 0-9642636-1-0. 112 pages.

Turner, William J. & Jack J. Heyman (1960) Journal of Organic Chemistry, 25: 2250–2251. “The Presence of Mescaline in Opuntia cylindrica.”

Tursch, B. et al. (1965) Tetrahedron Letters, 47: 4161–4166. “Structure de l’acide mesembryanthemoidigenique, triterpene nouveau des cactacees.” (B. Tursch, J. Leclercq & G. Chiurdoglu)

Udenfriend, S. & J.R. Cooper (1952) Journal of Biological Chemistry, 196 (1): 227–223. “The chemical estimation of tyrosine and tyramine.”

Udenfriend, S. et al. (1959) Archives of Biochemistry and Biophysics, 85 (2): 487–490. “Physiologically active amines in common fruits and vegetables.” (Sidney Udenfriend, Walter Lovenberg & Albert Sjoerdsma)

Ulett, George A. (1953) American Journal of Psychiatry, 109 (10): 741–748. “Preliminary observations on convulsive and subconvulsive treatments induced by intermittent photic stimulation.”

Umberger, C.J. (1954) in T.A. Gonzales, M. Vance, M. Halpern & C.J. Umberger (eds.) Legal Medicine, Pathology and Toxicology. 2nd Edition. Appleton-Century-Crofts: New York.

Underhill, Ruth (1952) Proceedings of the XXXth International Congress of Americanists, 143–148. “Peyote.”

Underhill, Ruth (1957) Ann. Am. Acad. Political and Social Sciences, 311: 127–136. “Religion Among American Indians.”

Unger, S.E. et al. (1980) Journal of Natural Products, 43 (2): 288–293. “Chemotaxonomy of Columnar Mexican Cacti by Mass Spectrometry/Mass Spectrometry” (S.E. Unger, R.G. Cooks, R. Mata & J.L. McLaughlin)

Unger, Sanford M. (1963)a LSD, Mescaline, Psilocybin and Psychotherapy: An Annotated Chronology. Washington, DC: National Institute of Mental Health

Unger, Sanford M. (1963)b Psychiatry. Journal for the Study of Interpersonal Processes. 26 (2): 111–125. “Mescaline, LSD, Psilocybin and Personality Change: A Review.”

Unger, Sanford M. (1965) LSD and Psychotherapy: A Bibliography of the English-Language Literature. pp. 241–248 in The Psychedelic Reader (Weil, G.M. et al. Editors).

United Nations (1989) Recommended methods for testing peyote cactus (mescale buttons) and mescaline and Psilocybe mushrooms/psilocybin. Manual for use by national narcotic laboratories. United Nations Office on Drugs and Crime; NewYork. (United Nation’s publication ST/NAR/19 — st-nar-19.pdf)

United Nations (2006) Multilingual Dictionary of Narcotic and Psychotropic Substances Under International Control. United Nations Office on Drugs and Crime. NewYork. (UN publication ST/NAR/1/Rev.2)

Uphof, J.C. Th. (1968) Dictionary of economic plants. 2nd edition. J. Cramer.

Urbina, Manuel (1900) Anales del Museo Nacional de México, 7: 26–48. “El Peyote y el Ololiuhqui.”

US Army (1974) Tactical Land Clearing, [US Army Field Manual 5-164 (FM 5-164)] Chapter Three: “Clearing methods and techniques.”

Usdin & Usdin (1961) Proc. Soc. Exp. Biol. Med. 108: 461.

Usdin, Earl & Daniel H. Efron (1979) Psychotropic Drugs and Related Compounds. Second Edition. Pergamon Press. 791 pp. ISBN# 0 08 025510 8. [First edition was published in 1972 by the US HEW]

USFWS (2001) AESO/SE 2-21-01-F-189.  (Formal U.S. Fish & Wildlife Service consultation for the Pleasant Valley Allotment.) Prepared for John C. Bedell, 30 November, 2001. [Posted online at: http://www.fws.gov/southwest/es/Arizona/Documents/Biol_Opin/01189_Pleasant_Valley.pdf]

Uyeno, Edward T. (1966) Journal of Pharmaceutical Sciences.. 55 (2): 215–216. “Inhibition of Isolation-Induced Attack Behavior of Mice by Drugs.” [Mescaline inhibited but less so than LSD]

Valadez, Mariano & Valadez, Susana (1992) Huichol Indian Sacred Rituals. Dharma (Amber Lotus): Oakland. 111 pages. ISBN 0-945798-80-6.

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Van Den Berg, J.H (1951) Folia Psychiat. (Amst.) 54 (6): 385–406, “Ein Beitrag zur Psychopathogie des Meskalinrausches.” Abstract: Excerpta Medica, Section VIII. (1952), Vol. 5, No. 8; entry #3306.

van den Berg, Maria Elisabeth (1984) “Ver-o-Peso: The Ethnobotany of an Amazonian Market.” Pages 140–149 in: Ghillean T. Prance & Jacquelyn A. Kallunki (eds.) Ethnobotany in the Neotropics. Proceedings in the Neotropics Symposium Society for Economic Botany, 13–14 June, 1983. The New York Botanical Garden, Bronx, New York.] [aka Advances in Economic Botany, 1: 140–149]

Vanderveen, R.L. et al. (1974) Phytochemistry, 13 (5): 866–867. “N-Methyltyramine from Opuntia clavata.” (Randall L. Vanderveen, Leslie G. West & Jerry L. McLaughlin)

Van der Walt, S.J. & D.G. Steyn (1940) Onderstepoorte Journal of Veterinary Sciences and Animal Industry, 15: 261–277. “Recent Investigations Into the Toxicity of Known and Unknown Plants of the Union of South Africa.” (From Watt 1967)

Van Praag, H.M. (1982) Lancet, ii: 1259

Van Vunakis, H. et al. (1969) Biochemical Pharmacology, 18: 393–404. “Production and Specificity of Antibodies Directed Towards 3,4,5-Trimethoxyphenethylamine, 3,4-Dimethoxyphenethylamine and 2,5-Dimethoxy-4-methylamphetamine.” (Helen Van Vunakis, Hilda Bradvica, Phillipe Benda and Lawrence Levine.)

Van Welsum, R.A. (1973) Journal of Chromatography, 78: 237–240. “A simplified procedure for the identification of drugs from the illicit street market by thin-layer chromatography.”

Vanderveen, R.L. et al. (1974) Phytochemistry, 13 (5): 866–867. “N-Methyltyramine from Opuntia clavata.” (Randall L. Vanderveen, Leslie G. West & Jerry L. McLaughlin)

Vargas, Plutarco Naranjo (1959) Revista. Confederacion Medica Panamericana, 6: 1–8 [CA (1959) 53: 19151f-g.] [“Comparative study of harmine, lysergic acid diethylamide (LSD-25) and mescaline.”] (said by CA to include 33 references.)

Vaupel, Friedrich (1916) Monatsschrifte für Kakteenkunde, 26: 120–125. “Neue südamerikanische Kakteen.” [Pages 122–123: II. Cereus tacaquirensis Vaupel spec. nov.]

Vazquez-Cruz, M.A. et al. (2012) Journal of Food Science, 77 (4): C366-C373. “Effect of maturity stage and storage on flavor compounds and sensory description of berrycactus (Myrtillocactus geometrizans).” (Moises Alejandro Vazquez-Cruz, Sandra Neli Jimenez-Garcia, Irineo Torres-Pacheco, Salvador Horacio Guzman-Maldonado, Ramon Gerardo Guevara-Gonzalez, & Rita Miranda-Lopez)

Vecsey, Christopher (ed.) (1991) Handbook of American Indian Religious Freedom. New York: Crossroad. 176 pages. ISBN 0-8245-1067–4

Vellozo, Fr. Jose Mariano da Conceição [a Conceptione] (1823) Florae Fluminensis, vol 5, plate 18. “Icosandria Mongynia Cactus hexagonus.”

Verdeax, G. (1950) [Cited by Deniker 1957 but not listed among his references. Said to have shown that the alpha rhythm is blocked at the moment hallucinations begin.] The closest reference I can locate is Delay, Baruk, Verdeaux & Verdeaux.

Verpoorte, R. & A. Baerheim Svensen (1983) Chromatography
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Vignon, M.R. et al. (2004) Carbohydrate Research, 339: 123–131. “Arabinan–cellulose composite in Opuntia ficus-indica prickly pear spines.” (M. R. Vignon, L. Heux, M.-E. Malaininea & M. Mahrouz)

Vigueras, A. L. & L. Portillo (2001) Florida Entomologist, 84:493–498. “Uses of Opuntia species and the potential impact of Cactoblastis cactorum (Lepidoptera: Pyralidae) in Mexico.”

Vilcapoma, Graciela (2000) Quepo, 14: 59- “Frutas Silvestres de la Cuenca del Rio Chillón (Cactáceas).”

Viloria-Matos, A.J. et al. (2002) Rev. Fac. Agron., LUZ, 19: 324–331. “Estabilidad de betalaínas en pulpa de tuna (Opuntia boldinghii Britt. et Rose) sometidas a un proceso de liofilización.” (A.J. Viloria-Matos, D. Corbelli-Moreno, M.J. Moreno-Álvarez & D.R. Belén-Camacho) [from García Pantaleón et al. 2009]

Vinson, J.A. & J.E. Hooyman (1975) Journal of Chromatography, 105 (2): 415–417. “A universal thin-layer chromatographic visualization reagent for drugs.”

Vistoli, G. (1955) Bollettino Chimico Farmaceutico, 94: 133-?. “Application of a color reaction to the photometric determination of sympathomimetic amines of pharmaceutical importance.”

Vitalis, Daniel (2009a) “Ever Tried This PsychoActive Cactus?” [Online article at http://www.danielvitalis.com/2009/12/ever-tried-this-psychoactive-cactus/]

Vitalis, Daniel (2009b) “The Psychedelic Suguaro Cactus.” [http://www.youtube.com/watch?v=6_-kNjwVO2g]

Vivanco Hidalgo, Eliana (2001) “El San Pedro entre ‘el bien y el mal: prácticas, discursos y conflictos en torno asu consumo en el Valle de Vilcabamba, Ecuador.” Artículo presentado en el Congreso Internacional de LASA 2001. Washington D.C, Septiembre, 6–8, 2001-08-20 (http://lasa.international.pitt.edu/Lasa2001/VivancoHidalgoEliana.pdf)

Vivanco Hidalgo, Eliana (2000) “Vilcabamba: Conflictos culturales, prácticas y discursos en torno de uso del San Pedro.” Pontificia Universidad Católica del Ecuador, Facultad de Ciencias humanas, Departamento de Antropología. Disertación previa a la obtención de la Licenciatura en Antropología, Quito. 122 pages. [Cited in Glass Coffin 2010 as Vivanco, Eliana 2000 ‘‘Vilcabamba: conflictos culturales, pra´cticas y discursos en torno al uso del San Pedro. Thesis, Quito: PUCE.] Thusfar this document has been unobtainable via any available channels. [from Vivanco Hidalgo 2001 and also http://www.beisa.dk/Publications/BEISA%20Book%20pdfer/Capitulo%2019.pdf.

Vogel, J.H. et al. (2005) Journal of the American College of
Cardiology,
46 (1): 184–221. “Integrating
Complementary Medicine Into Cardiovascular Medicine. A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents.”
(J.H. Vogel, S.F. Bolling, R.B. Costello, E.M. Guarneri, M.W. Krucoff, J.C. Longhurst, B. Olshansky, K.R. Pelletier, C.M. Tracy, R.A. Vogel, R.A. Vogel, J. Abrams, J.L. Anderson, E.R. Bates, B.R. Brodie, C.L. Grines, P.G. Danias, G. Gregoratos, M.A. Hlatky, J.S. Hochman, S. Kaul, R.C. Lichtenberg, J.R. Lindner, R.A. O’Rourke, G.M. Pohost, R.S. Schofield, S.J. Shubrooks, C.M. Tracy & W.L. Winters, Jr)(Downloadable from http://content.onlinejacc.org/cgi/reprint/46/1/184.pdf)
Why is it that anything containing the words “Consensus” with regards to the process of scientific inquiry is increasingly causing me to be cautious about trusting its results?

Vogel, W.H. (1970) Biochem. Pharm. 19: 2663.

Vogel, W.H. et al. (1967) Int. J. Neuropsychiatry, 3: 292.

Vogel, W.H. et al. (1973) Psychopharmacologia, 30: 145–151. “Macromerine, Normacromerine and Bisnormacromerine: Non-Psychoactive Methylated Derivatives of Norepinephrine.” (W.H. Vogel, B.D. Evans, E.M. Bonnem, J.F. Fischer & J.L. McLaughlin)

Vogt, M. (1935) Archiv für Experimentelle Pathologie und Pharmakologie, 178: 560–576. “Die Verteilung von Arneneitstoffen auf verschiedene Regionen des Zentralnervensystems, Zugleich ein Betrag Zu Ihrer quantitativen Mikrobestimmung im Gewerbe Chinin und Mezkalin.”

Vollenweider, F. X. (2001) Dialogues in clinical neuroscience, 3: 265–279. “Brain mechanisms of hallucinogens and entactogens. “

Vollenweider, Franz X. & Michael Kometer (2010) Nature  Reviews Neuroscience, 11: 642–651 “The Neurobiology of Psychedelic Drugs.”

Von Euler, Ulf S. (1955) Noradrenaline. Charles C. Thomas, Springfield, Ilinois.

Von Euler, U. S. & S. Hellner (1951) Acta Physiologica
Scandinavica
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adrenaline and hydroxytyramine in urine.”

von Euler, U.S. & F. Lishajko (1961) Acta Physiologica
Scandinavica
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von Kamienski, Elard Stein (1957) Planta, 50: 315–330. “Untersuchungen über die flüchtigen amine der pflanzen. II. Mitteilung. Die amine von blüttenpflanzen und moosen.”

von Ladenberg, B. (1893) Monatsschrift für Kakteenkunde. 3: 70- . “Die Kakteen und Sukkulenten auf der internationalen Ausstellung in Gent.” [This includes the oldest photograph of a macrogonus that I can presently locate. See page 71.]

von Martius See as Martius

Von Reis Altschul, Siri (1973) Drugs and Foods from Little-Known Plants. Notes in Harvard University Herbaria. Harvard University Press. (Second printing in 1975.) ISBN 0-674-21676-8.

Von Studnitz (1968) Scand. J. Clin. Lab. Invest. 21: 333 [CA 70: 1799] “Urinary excretion of methoxy catechol amines in neuroblastoma.” (from Crosby & McLaughlin 1973)

Voogelbreinder, Snu 1999 & 2000 (personal communication)

Voogelbreinder, Snu (2009) Garden of Eden: The Shamanic Use of Psychoactive Flora and Fauna, and the Study of Consciousness. Snu Voogelbreinder.

Voss, A. (1872) Vilmorin’s Ilustrierte Blumengärtnerei, 368 (A. Siebert, ed.) “Genus 427. Ariocarpus Scheidw. Aloecactus.” [from Grym 1997 & Anderson 1980]

Voss, A. (1872) Vilmorins Ilustrierte Blumengärtneri, 368.

Voswinckel, Hugo (1912) Berichte der deutschen chemischen Gesellschaft, 45 (1): 1004–1006. “Über eine neue Synthese des Hordenins.”

Waalkes, T.P. et al. (1958) Science, 127 (3299): 648-650. “Serotonin, Norepinephrine, and Related Compounds in Bananas.” (T.P. Waalkes, A. Sjoerdsma, C.R. Creveling, H. Weissbach & S. Udenfriend)

Wadworth, A.N. & D. Faulds (1992) Drugs, 44: 1013–1032. “Hydroxyethylrutosides: A Review of Pharmacology and Therapeutic Efficacy in Veneous Insufficiency and Related Disorders.”

Waeber, A. (1912) St. Petersburg Medizinische Zeitschrift, 37: 17–20. “Zur Wirkung von Anhalonium Lewinii.”

Wagner, Günter (1932) Baessler-Archiv, 15: 59–144. “Entwicklung und Verbreitung des Peyote-Kultes.”

Wagner, H. & J. Grevel (1982a) Planta Medica, 44: 36–40. “Neue herzwirksame Drogen II, Nachweis und Isolierung herzwirksamer Amine durch Ionenpaar-HPLC” [New Cardioactive Drugs II, Detection and Isolation of Cardiotonic Amines with Ionpair-HPLC] (Selenicereus grandiflorus )

Wagner, H. & J. Grevel (1982b) Planta Medica, 45: 95–97. “Cardioactive Drugs III, Cardioactive Amines from Echinocereus blanckii.”

Wagner, Hildebert (1969) Rauschgift-Drogen. [pp 85–91] Springer-Verlag: Berlin-Heidelberg-NewYork.

Walewski, Count Stefan Colonna (1955) Secrets of Caucasian Yoga. Falcon Press.

Walker, A.R. (1953) Bull. Inst. Étud. Centrafr. (N.S.) 5: 1940 / 6: 275–329. “Usages Pharmaceutiques des Plantes Spontanées du Gabon.” (From Watt 1967)

Wallace, Anthony F.C. (1956) Southwestern Journal of Anthropology, 12 (1): 1–21. “New religions among the Delaware Indians, 1600–1900.”

Wallace, Anthony F.C. (1959) A.M.A. Archives of General Psychiatry, 1 (July): 58-69. “Cultural Determinants of Response to Hallucinatory Experience.”

Wallace, Robert S. (1986) Cactus & Succulent Journal (US), 58: 35–38. “Biochemical taxonomy and the Cactaceae.”

Wallace, Robert S. & Arthur C. Gibson (2002) “Evolution and Systematics.” pages 1–21 (Chapter 1) in Nobel 2002

Wallraff, Günter (1968) Meskalin – ein Selbstversuch. Verlag Peter-Paul Zahl: Berlin.

Walpole, G.S. (1910) J. Chem. Soc. Trans. 97: 941–999. [from Reti 1953]

Walter, V.J. & W. Grey Walter (1949) Electroencephalography and Clinical Neurophysiology, 1 (1): 57–86. “The central effects of rhythmic sensory stimulation.”

Walter, William Gray (1946) Nature, 158: 540. “Analysis of the Electrical Response of the Human Cortex to Photic Stimulation.”

Walter, William Gray (1953) The Living Brain. Duckworth, 1953. [Also W.W. Norton, NewYork 1953.]

Walters, G.C. & P.D. Cooper (1968) Nature, 218: 298–300. “Alicyclic Analogue of Mescaline.”

Wanag, Gustav & Anna Dombrowski (1942) Berichte der Deutschen Chemischen Gesellschaft, 75: 82–86. “Verwendung von 2-Nitro-indandion-(1,3) für die Isolierung und Identifizierung organischer Basen. II. Mitteilung.”

Wani, M.C. et al. (1980) Journal of Chemical Research (M) 0301–0331. “X-ray crystal and molecular structure of the racemic, dimeric tetrahydroisoquinoline alkaloid Lophocine, probably an artefact [SIC], from Lophocereus schottii” (Mansukh C. Wani, James B. Thompson, Harold L. Taylor, Monroe E. Wall, Richard W. Miller & Andrea T. McPhail)

Waser, E. (1925) Helvetica Chimica Acta, 8: 758–773. “Untersuchungen in der Phenylalanin-Riehe. VI. Decarboxylierung des Tyrosins und des Leucins”

Waser, E. & H. Sommer (1923a) Helvetica Chimica Acta, 6: 54–61. “Untersuchungen in der Phenylalanin-Reihe. II. Synthese des 3,4-Dioxyphenyl-äthylamins”

Waser, E. & H. Sommer (1923b) Helvetica Chimica Acta, 6: 1797. (from Neme et al. 1977)

Wasson, R. Gordon (1961) Botanical Museum Leaflets. Harvard University, 19 (7): 137–162. “The Hallucinogenic Fungi of Mexico: An Inquiry Into the Origins of the Religious Idea Among Primitive Peoples.”

Wasson, R. Gordon (1968) SOMA: Divine Mushroom of Immortality. Mouton & Co.

Wasson, R. Gordon (1970)a Bulletin on Narcotics, 22 (3): 25–30. “Soma of the Aryans: An ancient hallucinogen?”

Wasson, R. Gordon (1970)b Indo-Iranian Journal, 12 (4): 286–298. “Soma: Comments inspired by Professor Kuiper’s review.”

Wasson, R. Gordon (1971) Journal of the American Oriental Society, 91 (2): 169–187. “The Soma of the Rig Veda: What was it?”

Wasson, R. Gordon (1972) Soma and the Fly-Agaric: Mr. Wasson’s Rejoinder to Professor Brough. Botanical Museum of Harvard University.

Wasson, R. Gordon (1978) Botanical Museum Leaflets. Harvard University, 26 (6): 211–223. “Soma brought up-to-date.”

Wasson, R.G. et al. (1978) The Road To Eleusis: Unveiling the Secret of the Mysteries. (R. Gordon Wasson, Albert Hofmann & Carl A.P. Ruck) Harcourt, Brace, Jovanovich. [See also as (1995) El Camino a Eleusis. Fondo de Cultura Económica. 235 pp. ISBN 968-16-0655-8.]

Wasson, R. Gordon et al. (1986) Persephone’s Quest. Entheogens and the Origins of Religion. Yale University Press. ISBN 0-300-05266-9. 257 pages. (R. Gordon Wasson, Stella Kramrisch, Jonathan Ott & Carl A.P. Ruck) [See also as (1996) La Búsqueda de Perséfone. Fondo de Cultura Económica. 339 pp. ISBN 968-16-3695-3.]

Watanabe, K. et al. (1995) Biol. Pharm. Bull, 1995, 18, 696. (K. Watanabe, Y. Kayano, T. Matsunaga, I. Yamamoto and H. Yoshimura, )

Waterhouse, G. (1932) Simon van der Stel’s Journal of his Expedition to Namaquoland 1685–6. Longmans, Green & Co.: London.

Watermulder, G.A. (1914) Report of the Thirty-Second Annual Lake Mohonk Conference on the Indian and Other Dependent Peoples, 68–76. “Mescal”

Watt, John Mitchell & Maria Gerdina Breyer-Brandwijk (1962) The Medicinal and Poisonous Plants of Southern and Eastern Africa. Second Edition. E. & S. Livingstone, Ltd. 1457 pp.

Watt, John Mitchell (1967) Lloydia, 30 (1): 1–22. “African Plants Potentially Useful in Mental Health.”

Weber (1902) Monatsschr. Kakteenk. 12: 21 [Cereus bolivianus] [From Britton & Rose] See as Schumann 1902

Webster (1972) Webster’s English Dictionary, Pyramid Communications, Inc.

Weckerle, B. et al. (2001) Flavour Fragrance Journal, 16: 360–363. “Cactus pear (Opuntia ficus indica) flavour constituents — chiral evaluation (MDGC-MS) and isotope ratio (HRGC-IRMS) analysis.” (Bernhard Weckerle, Renate Bastl-Borrmann, Elke Richling, Katja Hör, Christiane Ruff & Peter Schreier)

Weil-Malherbe, H. & L.B. Bigelow (1968) Anal. Biochem. 22: 321–334.

Weil, Andrew & Winifred Rosen (1983) Chocolate to Morphine. Understanding Mind-Active Drugs. Houghton Mifflin Co, ISBN 0-395-33108-0/ 0-395-33190-0 (pbk.)

Weiner, C.D. & M.A. Collins (1978) Biochemical Pharmacology, 27: 2699–2703. “Tetrahydroisoquinolines derived from catecholamines or DOPA: Effects on brain tyrosine hydroxylase activity.”

Weiner, H. (1980) Substance & Alcohol Actions/Misuse, 1 (3): 317–322. “Estimation of the in vivo concentration of salsolinol and tetrahydropapaveroline in rat brain after the administration of ethanol.”

Weiner, N. (1980b) “Norepinephrine, epinephrine, and the sympathomimetic amines.” pages 138–175 in, A.G. Gilman, L. S. Goodman & A. Gilman (eds.) Goodman and Gilman’s The Pharmacological Basis of Therapeutics (6th Ed.). New York: Macmillan.

Weiner H. (1981) Federation Proceedings, 40 (7): 2082–2085. “Possible steady-state concentrations of tetrahydroisoquinolines in brain after the consumption of ethanol.”

Weiner, N. et al. (1962) Journal of Pharmacology and Experimental Therapeutics, 137: 47–55. “The Ability of Tyramine to Liberate Catecholamines IN VIVO” (N. Weiner, P.R. Draskóczy and W.R. Burack)

Weir Mitchell, S. (1896) British Medical Journal, 2: 1625–1629. “Notes upon the Effects of Anhelonium [sic] Lewinii (The Mescal Button).”

Weisenborn 1978 (in the literature) apparently refers to J. Weisenborn (Unpublished data)

Weisenborn, J. (Unpublished data). Kapadia et al. 1970c mentions that Dr. Weisenborn (at Squibb) first presented this in a discussion during the 5th Ann. Meeting of the American Society of Pharmacognosy, June 22–25, 1964 (Pittsburgh, PA) and that it was planned for publication submission. Appears cited numerous places but apparently either no details were ever published for the isolation or the structural determination of Tehuanine or it was published under the name of a different lead author.

Welch, A.S. & B.L. Welch (1969) Anal. Biochem. 30: 161–179.

Wellman, Klaus F. (1978a) Journal of the American Medical Association, 239 (15): 1524–1527. “North American Indian Rock Art and Hallucinogenic Drugs.”

Wellman, Klaus F. (1978b) A Survey of North American Indian Rock Art. Akademisch-Druck und Verlagsanstalt: Austria.

Weltman [sp?] and associates (1968) Journal of Experimental Medicine and Surgery, 26: 187. [from Aboul-Enein 1973]

Weniger, Del (1984) Cacti of Texas and Neighboring States. Austin: University of Texas Press.

Werdermann, Erich (1931) pages 73, 101 in Backeberg Neue Kakteeen

Werdermann, Erich (1934) Kakteenkunde, 9: 176. [as Thelocactus lophophoroides]

Werdermann 1931 See within Backeberg Neue Kakteeen

Werdermann, Erich (1933) Brasilien und seine Säulenkakteen. [Werdermann correctly assigns identity to what Glazious mistook for Cereus macrogonus but fails to acknowledge Schumann’s corrections.]

Werfel, Franz (1976) Star of the Unborn. Bantam: NY. 627 pages. [First published in 1946 by Viking: NY. 645 pp.]

Wertham, Frederick (1952)a Atlantic Monthly, 189 (March): 52–55. “A study of pain.” [mescaline and pain]

Wertham, Frederick (1952)b “A psychosomatic study of myself.” pp. 102–118 in Max Pinner & Benjamin F. Miller (eds.) When Doctors Are Patients. NewYork: Norton. [mescaline and pain]

Wertham, Frederick & Manfred Beuler (1932) Archives of Neurology and Psychiatry, vol. 28: “Inconstancy of the Formal Structure of the Personality: Experimental Study of the Influence of Mescaline on the Rorschach Test.”

West, Leslie G. & Jerry L. McLaughlin (1973) Lloydia, 36 (3): 346–348. “Cactus Alkaloids. XVIII. Phenolic β-Phenethylamines from Mammillaria elongata.”

West, Leslie G. & Jerry L. McLaughlin (1977) Lloydia, 40 (5): 499–504. “Triterpenes from the Button Cactus, Epithelantha micromeris.

West, L.G. et al. (1974) Phytochemistry, 13 (3): 665–666. “β-Phenethylamines from the Genus Gymnocactus.” (L.G. West, R.L. Vanderveen & J.L. McLaughlin)

West, L.G. et al. (1975) Phytochemistry, 14: 291–292. “Pilocereine from Lophocereus schotti Formae Monstrosus and Mieckleyanus.” (Leslie G. West, Jerry L. McLaughlin & W. Hubert Earle)

Westlund, Derek in Adam Gottlieb (1997) Peyote and Other Psychoactive Cacti.

Whaley, W.M. & T.R. Govindachari (1951) Organic Reactions, 6: 151–190. “The Pictet-Spengler synthesis of tetrahydroisoquinolines and related compounds.”

Wheatley, M.D. & F.W. Schueler (1950) Electroencephalography and Clinical Neurophysiology, 2: 226. “A synergism between mescaline and rhythmic stimulation by light.” [Abstract of paper presented at the meeting of the Southern Electroencephalographic Society, Nov. 30, 1949, New Orleans, Louisiana.] [Showed low doses of mescaline, too low to produce visual effects were “adequate for the production of striking visual effects when these subjects were placed, with eyes closed, in front of a flashing light of frequency approximating that of the normal alpha rhythm.”]

Wheaton, T.A. & Ivan Stewart (1970) Lloydia, 32 (2): 244–254. “The Distribution of Tyramine, N-Methyltyramine, Hordenine, Octopamine, and Synephrine in Higher Plants.” Page 247

Whitby, L.G. et al. (1961) Journal of Pharmacology & Experimental Therapeutics, 132: 193–201. “The fate of H3[sic]-norepinephrine in animals.” (L.G. Whitby, J. Axelrod & H. Weil-Malherbe)

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White, E.P. (1944)a New Zealand Journal of Science and Technology, 25, Sec. B; 4: 139–142. “Alkaloids of the Leguminosae. Part IX.- Isolation of β-phenethylamine from Acacia species.”

White, E.P. (1951) New Zealand Journal of Science and Technology, 33, Sec. B; 1: 54–60. “Part XXII.- Legumes Examined for Alkaloids- Additions and Corrections.”

White, E.P. (1954) New Zealand Journal of Science and Technology, 35, Sec. B; 6: 451–455. “Alkaloids of the Leguminosae. Part XXIII.- The Occurrence of N-Methyl-β-phenethylamine in Acacia prominens A. Cunn..”

White, E.P. (1957) New Zealand Journal of Science and Technology, 38, Sec. B; 7: 718–725. “Part XXVI: Examination of Further Legumes, Mainly Lupinus and Acacia species for Alkaloids.”

White, E.P. (1970) New Zealand Journal of Science, 13: 359.

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Whitley, David S. (1994)b “Shamanism, Natural Modeling and the Rock Art of Far Western North American Hunter-Gatherers.” in: Shamanism and Rock Art in North America. Rock Art Foundation, Special Publication 1: San Antonio Texas.

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Wiedman, Dennis (1985) American Indian Art Magazine, 10 (3): 38–45. “Staff, Fan, Rattle and Drum: Spiritual and Artistic Expressions of Oklahoma Peyotists.”

Wiedman, Dennis & Candace Green (1985) American Indian Art Magazine, 13 (4): 32–41. “Early Kiowa Peyote Ritual and Symbolism: The 1891 Drawing Books of Silverhorn (Huangooah).”

Wijeratne, E.M.K. et al. (2006) Bioorganic & Medicinal Chemistry 14: 7917–7923. “A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity.” (E. M. Kithsiri Wijeratne, Thomas J. Turbyville, Anne Fritz, Luke Whitesell & A. A. Leslie Gunatilaka)

Wikler, Abraham (1952) American Journal of Psychiatry, 108 (8): 590–599. “Mechanisms of action of drugs which modify personality functions.”

Wikler, Abraham (1954) Journal of Nervous and Mental Disease, 120 (3–4): 157–175. “Clinical and electroencephalographic studies on the effects of Mescaline, N-allylnormorphine and morphine in man.”

Wikler, Abraham (1957) The Relation of Psychiatry to Pharmacology. Baltimore: Williams and Wilkins. [Summary of psychiatric and pharmacological work on mescaline.]

Wilcox, R.W. (1898) New York Lancet, p. 81. “Pellotine.”

Wild, H. (1953) A Southern Rhodesian Botanical Dictionary of Native and English Plant Names. Salisbury, Rhodesia. (From Watt 1967)

Willaman 1961 (in the literature) meant Willaman & Schubert 1961

Willaman, J.J. & Bernice G. Schubert (1961) Alkaloid-bearing plants and their contained alkaloids. USDA Technical Bulletin No. 1234. Agricultural Research Service, USDA, US Government Printing Office, Washington, DC, 1961.

William (1967) (in the literature) meant Geber, William F. (1967)

Willner, P. (1983) Brain Res. Rev. 6: 211

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Winters, J.C. (1971) Journal of Pharmacology and Experimental Therapeutics, 178: 625–630. “Tolerance to a behavioral effect of lysergic acid diethylamide and cross-tolerance to mescaline in the rat: absence of a metabolic component.”

Winter, Hildegard (1956) H. WINTER Kakteen Cacti Cactées Samen — seed — semence FRANKFURT A.M – FECHENHEIM. 36 pages

Winter, Hildegard (1957) H. WINTER Kakteen Cacti Cactées Samen — seed — semence FRANKFURT A.M – FECHENHEIM. 36 pages

Winter, Hildegard (1958) H. WINTER Kakteen Cacti Cactées Samen — seed — semence FRANKFURT A.M – FECHENHEIM. 40 pages

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Wisser, H & D. Stamm (1969) Zeit. Klin. Chem. Klin. Biochem. 7: 631–648.

Witkiewicz, Stefan L. (1932) Nikotyna-alcohol-kokaina-peyotl-eter. Warsaw.

Witt, P.N. (1951) Experientia, 7: 310–311. “d-Lysergsäure-diäthylamid (LSD 25) im Spinnentest.” [Also discusses mescaline.]

Witt, Peter N. (1956) Arzneimittel-Forschung, 6 (10): 628-635. “Der Netzbau der Spinne als Test zur Prüfing zentralnervös angreifender Substanzen.”

Witt, P.N. & R. Weber (1956) Monatsschrift fur Psychiatrie und Neurologie, 132: 193–207. “Biologische Prüfung des Urins von drei Kranken mit akut psychotischen Zustandsbildern auf pathogene Substanzen mit dem Spinnentest.”

Wohlpart, A. (1967) Dissertation. University of Texas at Austin. [From Wohlpart & Mabry 1968]

Wohlpart, A. & T.J. Mabry (1968) Taxon, 17: 148–152. “The Distribution and Phylogenetic Significance of the Betalains With Respect to the Centrospermae.”

Wolbach, A.B. et al. (1962)a Psychopharmacologia, 3 (1): 1–14. “Cross-tolerance between mescaline and LSD-25, with a comparison of the mescaline and LSD reactions.” (A.B. Wolbach Jr., Harris Isbell & E.J. Miner)

Wolbach, A.B. et al. (1962)b Psychopharmacologia, 3 (3): 219–223. “Comparison of Psilocin with Psilocybin, Mescaline and LSD-25.” (A.B. Wolbach Jr., E.J. Miner & Harris Isbell)

Wolf, R. (1952) Deutsche Medizinische Wochenschrift, 77 (6): 168–170. “Das Raum- und Zeiterleben unter abnormaler Bedingungen, besonders im Meskalinrausch.” [also see Abstract: Excerpta Medica, Section VIII. (1952), Vol. 5, No. 8; entry #3307.]

Wollenweber, Eckhard & Marion Dörr (1995) Biochemical Systematics and Ecology, 23 (5): 577. “Wax Composition of the Two Cacti Hylocereus purpusii and Stenocereus benecki.”

Wong, D. L. (2003) Endocrine Pathology, 14(1): 25–36. “Why is the adrenal adrenergic?”

Wood, Richard: Wooden Penny Trading Post; 409–297-8953, FAX 409-265-6813. [Literature obtained at the Intertribal Pow-wow.]

Woodard, R.W. et al. (1978) Acta Chemica Scandinavica, B, 32 (8): 619–623. “The absolute configuration of the cactus alkaloid (-)-calipamine” (Ronald Woodard, J. Cymerman Craig and Jan G. Bruhn)

Woods, L.A. et al. (1951) J. Pharm. Exp. Ther. 101: 205. (in the literature) meant Cochin et al. 1951

Woods, L.A. et al. (1951) Journal of Pharmacology and Experimental Therapeutics, 101 (2): 188–199. “Estimation of amines in biological materials with critical data for cocaine and mescaline.”

Woodward, Hope Draper (1991) M.A. Thesis University of Texas at Austin. “Ashaninca Shamanic Healing Ritual and Song.”

Woolley, D.W. & E. Shaw (1954) Proceedings of the National Academy of Sciences, (Washington, DC) 40: 228–231. “A biochemical and pharmacological suggestion about certain mental disorders.”

Wright, Jon (1994) Peyote in Sanskrit. Naked Bums. 98 pages. 0-9643358-0-8 [? No idea what this is. It is listed in Books-In-Print.]

Wu, G. et al. (1994) Industrial & Engineering Chemistry Research, 33: 718–723. “Improved Alkaline Oxidation Process for the Production of Aldehydes (Vanillin and Syringaldehyde) from Steam-Explosion Hardwood Lignin.” (Guoxiong Wu, Michele Heitz, & Esteban Chornet)

Wu, J. et al. (1980) Journal of Natural Products, 43 (2): 270–277. “Alkaloids of Thalictrum. XXXII. Isolation and Identification of Alkaloids From Thalictrum revolutum DC. Fruit.” (Jinn Wu, Jack L. Beal, Wu-Nan Wu & Raymond W. Doskotch)

Wu, S.H. et al. (2008) Journal of Basic Microbiology 48: 140–142. “A new spiroketal from Aspergillus terreus, an endophytic fungus in Opuntia ficus-indica Mill.” (Shao-Hua Wu, You-Wei Chen, Sheng Qin & Rong Huang)

Wu, W.-N. et al. (1980) Journal of Natural Products, 43 (1): 143–150. “Alkaloids of Thalictrum XXX. Eleven Minor Alkaloids From Thalictrum rugosum.” (Wu-Nan Wu, Jack L. Beal & Raymond W. Doskotch)

Wu, X. et al. (2011) J Asian Nat Prod Res. 13 (8): 728–733. “Three new glycosides from Hylocereus undatus.” (X. Wu, Y. Wang, X.J. Huang, C.L. Fan, G.C. Wang, X.Q. Zhang, Q.W. Zhang & WC. Ye)

Wybraniec, Sławomir & Yosef Mizrahi (2002) Journal of Agricultural and Food Chemistry, 50 (21): 6086–6089. “Fruit Flesh Betacyanin Pigments in Hylocereus Cacti”

Wybraniec, Sławomir & Barbara Nowak-Wydra (2007) Journal of Agricultural and Food Chemistry, 55 (20): 8138–8143. “Mammillarinin: A New Malonylated Betacyanin from Fruits of Mammillaria.”

Wybraniec, S. et al. (2001) Phytochemistry, 58 (8): 1209–1212. “Betacyanins from vine cactus Hylocereus polyrhizus.” (Sławomir Wybranieca, Itzhak Platzner, Shimona Geresh, Hugo E. Gottlieb, Marcela Haimberg, Michael Mogilnitzki & Yosef Mizrahi)

Wybraniec, S. et al. (2007) Phytochemistry, 68: 251–259. “Minor betalains in fruits of Hylocereus species.” (Sławomir Wybraniec, Barbara Nowak-Wydra, Katarzyna Mitka, Piotr Kowalski & Yosef Mizrahi)

Wybraniec, S. et al. (2009) Journal of Chromatography, A, 1216 (41): 6890–6899. “Separation of polar betalain pigments from cacti fruits of Hylocereus polyrhizus by ion-pair high-speed countercurrent chromatography.” (S. Wybraniec, P. Stalica G. Jerz, B. Klose, N. Gebers, P. Winterhalter, A. Spórna, M. Szaleniec & Y. Mizrahi)

Wyler 1979 should read Wyler & Meuer 1979

Wyler, Hugo & Ursula Meuer (1979) Helvetica Chimica Acta, 62 (4): 1330–1339. “Zur Biogenese der Betacyane: Versuche mit [2-14C]-Dopaxanthin.“

Wynd, F.L. (1944) The American Midland Naturalist, 200–235. “Geological and Physiographic Background of the Soils in the Lower Rio Grande Valley, Texas.”

Wysong, E. et al. (1994) Social Problems, 41 (3): 448–472. “Truth and DARE: Tracking Drug Education to Graduation and as Symbolic Politics.” (Earl Wysong, Richard Aniskiewicz & David Wright)

Yácovleff, Eugenio & Fortunato L. Herrera (1934) Revista del Museo Nacional. Lima 3 (3): 243–322. “El Mundo Vegetal de Los Antigous Peruanos.” [References are in Yácovleff & Herrera 1935]

Yácovleff, Eugenio & Fortunato L. Herrera (1935) Revista del Museo Nacional. Lima 4 (1): 31–102. “El Mundo Vegetal de Los Antigous Peruanos.”

Yamada et al. (1981) Tetrahedron Letters, 22: 3869

Yamamoto 1972 See as Palomino Yamamoto 1972

Yamanaka, Yasumitsu (1971) Japanese Journal of Pharmacology, 21: 883–836. “Effect of salsolinol on rat brain and liver monoamine oxidase.”

Yamanaka, Y. et al. (1970) Nature, 227: 1143–1144. “Salsolinol, an alkaloid derivative of dopamine formed in vitro during alcohol metabolism.” (Yasumitsu Yamanaka, Michael J. Walsh and Virginia E. Davis)

Yang, T.-H. & C.M. Chen 1970 J. Chin. Chem Soc (Taipei) 17: 235–242; (CA 73: 99072s & 74: 100254g

Yang, T.-H. & G.J.H. Fan (1966) T’ai-Wan Yao Hsueh Tsa Chih, 18 (1): 33–36. [CA (1970) 72: 136333e.]

Yang, T.-H. et al. (1962) Yakugaku Zasshi, 82: 811. [CA 58: 7991]

Ye, Y. et al. (1998) Journal of Natural Products, 61: 456–460. “New Triterpenes from Machaerocereus eruca.” (Yang Ye, Kaoru Kinoshita, Kiyotaka Koyama, Kunio Takahashi, Norio Kondo & Hiroshi Yuasa)

Yi, Y. et al. (2011) Zhong Yao Cai, 34 (5): 712–716. “[Studies on the flavonoids from the flowers of Hylocereus undatus].” [Article is in Chinese] (Y. Yi, X. Wu, Y. Wang , W.C. Ye & Q.W. Zhang)

Yue, M.-E. et al. (2005) Journal of Separation Science, 28 (4): 360–364. “Simultaneous determination of noradrenaline and dopamine in Portulaca oleracea L. by capillary zone electrophoresis.” (Mei-E Yue, Ting-Fu Jiang & Yan-Ping Shi)

Yurashevskii, N.K. (1939) J. Gen. Chem. USSR, 9: 595–597 [From Reti 1950 & White 1954]

Yurashevskii, N.K. (1941) J. Gen. Chem. USSR, 11: 157–162. [From Reti 1950 & White 1954]

Zachar, M. et al. (1996) Rod Turbinicarpus (M. Zachar, R. Staník, A. Lux & I. Dráb)

Zhang, F & M. Lu (1992) Tianran chanwu Yanjiu Yu Kaifa 4: 15–22. “Natural pigment from fruit of Opuntia dillenii.” [from Gupta et al. 2002]

Zeller, E. Albert (1963) Annals of the New York Academy of Science, 107 (3): 811–821. “A New Approach to the Analysis of the Interaction Between Monoamine Oxidase and its Substrates and Inhibitors.”

Zeller, E.A. et al. (1958) Journal of Pharmacology and Experimental Therapeutics, 124 (1): 282–289. “Degradation of Mescaline By Amine Oxidases.” (E. Albert Zeller, James Barsky, Elaine R. Berman, Marshall S. Cherkas & James R. Fouts)

Zeller, E.A. et al. (1976) Experientia, 32 (11): 1453–1454. “Mescaline: its effects on learning rate and dopamine metabolism in goldfish (Carassius auratus).” (Zeller EA, Couper GS, Huprikar SV, Mellow AM, Moody RR.)

Zenteno, E. et al. (1988) FEBS Letters, 238(1): 95–100. “Purification and partial characterization of two lectins from the cactus Machaerocereus eruca.” (Edgar Zenteno, Henri Debray & Jean Montreuil)

Zenteno, E. et al (1995) Glycoconjugate Journal, 12 (5): 699–706. “Specificity of the isolectins from the plant cactus Machaerocereus eruca for oligosaccharides from porcine stomach mucin.” (E. Zenteno, L. Vázquez, R. Chávez, F. Córdoba, J.M. Wieruszeski, J. Montreuil & H. Debray)

Zhang, F. & M. Liu (1992) Tianran Chanwu Yanjiu Yu Kaifa 4: 15–22. [Natural pigments from fruit of Opuntia dillenii] in Chinese with English Abstract. (See also 1992 Chemical Abstracts 117, 190506 z)

Zhang, J.-Y. et al. (2002) Analytica Chimica Acta, 471: 203–209. “Quantification of noradrenaline and dopamine in Portulaca oleracea L. by capillary electrophoresis with laser-induced fluorescence detection.” (Ji-you Zhang, Xing-guo Chen, Zhi-de Hu & Xiao Ma)

Zhao, X. et al. (2002) Chin. J. Integrated Tradition. Western Med. 8: 215- 218. “Clinical Observation of Opuntia dillenii Tablet in Treating Type 2 Diabetes Mellitus.” (X. Zhao, J. Yang, Z. Tong, Y. Zhou, W. Zhang, S. Qi, & G. Yuan)

Zingg, Robert Mowry (1938) The Huicholes: Primitive Artists. Stechter Publ.: NY. Also as (1982) Los huicholes: (2 volumes) INI: Mexico.

Zuccarini, Joseph Gerhard (1832–1847?) Plantarum novarum vel minus cognitarum, quae in horto botanico herbarioque regio Monacensi servantur. München :Königlich Bayerische Akademie der Wissenschaften.

Zucker, K. (1928) Archiv für Psychiatrie, 83: 706–754. “Experimente über Sinnestäuschungen.”

Zucker, K. (1930) Zentralblatt für die gesamte Neurologie und Psychiatrie, 56: 447–448. “Ueber die Zunahme spontaner Halluzinationen nach Meskalin.”

Zwicky, E. (1914) “Über Channa, ein Genussmittel der Hottentotten (Mesembrianthemum expansum L. und tortuosum L.)” Ph.D. Dissertation, Zurich. [Wurder eins Doktors der Naturwissenschaften, Eidgenossichen Technischen Hochschule in Zurich] [Variously cited as “Thesis Conf. Tech., High School, Zurich.” or “Ph.D. Dissertation, Zurich”]

Occurrences endnotes

Occurrences of Mescaline Endnotes

Note 1: Also rendered as Boedecker. 

Note 2 (Aztekium): The polycephalic (multiheaded) specimens that are depicted of these typically unbranched plants arose in greenhouse situations. This is believed to be the result of routine pesticide application.

Aztekium ritteri

Aztekium ritteri

Note 2 (Gymnocalycium): Colorless birefringent crystals, n 1.544, mp 160-162° were claimed to show the “reactions of mescaline”. 

Note 3:  In my only query on the matter (a pay-phone call made to the DEA in early 1996), I was informed that the US Drug Enforcement Agency knows nothing about the existence of another peyote species. They were very reluctant to even discuss the matter with me. They did say that since state law prohibits possession of the drug, they would definitely arrest a person for growing peyote, in any quantity, even if for horticultural purposes. (They also mentioned that they recently did.) They also said that they would definitely arrest anyone who had a plant that they felt even “looked like peyote”. When asked if the known lack of mescaline would make it legal to grow, they remarked it would “make a good legal defense” but pointed out it might take a week or more to get the test results back from the lab, during which time one might have to stay jailed. They agreed with my assertion that their idea of proving the plants in question did not contain mescaline would require their destruction.

Even worse, their idea of testing was said to consist of determining how many “dosage units” are in the cactus material on hand, not simply whether it contains mescaline or not. This would require the use of all plants present, not just a small sample. (Mescaline’s presence or absence could be determined with even a small portion sampled from a living cacti, without requiring its death.)

The logic on this bring to mind the old test for pearls of dropping them into a glass of red wine, (if it ruins them they were real, if it doesn’t they are fake), or the tests for ‘proving’ someone a witch by dunking them repeatedly under water or crushing them with rocks under a board (if they live they are a witch, if they die, they were not).

The Inquisition still lives but the modern ‘witch hunt’ is now for drugs.

Ott’s notion concerning the evolution of the Theocratic Inquisition into a Pharmacratic Inquisition is very accurate.

The actions of the 1997 Congress could be construed as making even the hairs from a Lophophora diffusa illegal but so far as I can tell that issue has never gone to court.

Note 4: This was L. diffusa being analyzed as L. echinata. This is an incorrect designation for L. diffusa not uncommonly, but unfortunately, encountered in European collections.

  Croizat described L. echinata as being from Texas and went on to describe L. diffusa as L. echinata var. diffusa. This, Backeberg’s heavy reliance on Croizat’s assessment of Lophophora and an apparent overall dislike of trinomials has sadly contributed to the predominance of L. diffusa as the plants labeled L. echinata  in Europe.

  L. echinata (L. williamsii var. echinata sensu Weniger) is also commonly used in the US for the greyish, larger & higher alkaloid material found in southern Trans-Pecos Texas and southward into Coahuila.

  It is probably, at least partly, synonymous with the Coahuilan material NOW being called L. decipiens by European cactophiles. Some of what is regarded as L. decipiens is obviously L. fricii.

Note 5: Possible error on my part. Štarha 1997 lists this as O-Methylanhalinine which I assumed was a typo (as a compound with this name cannot physically exist).

Note 6: This is not the major alkaloid when compared to the pellotine present.

Note 7: There appears to be some discrepancy as this is not a minor alkaloid with regards to the mescaline reported to be present.

Note 8: Also described as Lophophora williamsii var. koehresii (Ríha) Grym. See Grym 1997.

Note 9: In Štarha & Kuchyňa 1996 this appears as a typo (anhalamine is listed twice). I based this assignment on a comparison of the gc value with those in Štarha’s other papers.

Note 10: I am apparently lacking the right diacritics. “íi” needs cedillas on both characters.

Note 11: And also being sold as ground Baby Hawaiian Woodrose during the same time frame. It is impossible to confuse the effects produced by these very different drug plants.

Datura sp.

Datura sp.

Note 12: The mistake of jumping from the assumption of “probably” directly into ‘fact’ was made in the same paper where he does an amazing job of disentangling the confusion which at that time surrounded cohoba and tobacco. Safford correctly associated of cohoba, parica and niopa (and other local names) with Anadenanthera peregrina (then known as Piptadenia peregrina) and described the use of its seeds as snuffs and, in some cases, as an enema (citing Spix & Martius 1831).

Anadenanthera_seeds_compared

See also Safford 1916b or refer to Some Simple Tryptamines PDF or see the Anadenanthera section in the online Ayahuasca book at the Erowid website for more details and a discussion of various snuff sources.

  An interesting observation was made by Safford concerning Siméon 1885. Rémi Siméon is said to have [correctly] stated that Teonanacatl was a small mushroom, that tastes bad, causes hallucinations and intoxication and was used for fevers. Safford somehow concluded: “Three centuries of investigation have failed to reveal an endemic fungus used as an intoxicant in Mexico, nor is such a fungus mentioned in either works on mycology or pharmacology, yet the belief prevails even now there is a narcotic fungus…” Safford then goes on to dismiss this persistent belief as an error, concluding that the sacred fungus was actually a dried cactus. [One must wonder just what three centuries of investigations Safford refers to since both early Spanish and Mexican investigations would have only had its destruction (and obliteration from common knowledge) in mind and the Spanish chroniclers certainly mentioned AND depicted mushrooms being used in a supernatural context.]

  What is perhaps more puzzling is that if he had consulted any of a number of medical or mycological journals of his day he would have found ample references to the always non-fatal accidental poisonings characterized by “gay hilarity” and colored hallucinations. A number of references, in Africa, Europe and the US, existed, even in the 19th century, as to the effects of the accidental, always non-lethal, “poisonings” by Paneolus spp. and other Psilocybin containing mushrooms. [See our forthcoming work on Psilocybin containing plants for references and more detail.]

To add a strange twist to what Safford’s claims, on page 264 in John Borg 1937, appears these curious words that seem to diverge in the opposite direction:
”    This is the famous mescal or peyotle of the ancient Mexicans, who used to cut off the top of the plant and eat it at their festivals, an evil practice which is now prohibited by law [Ed.: this refers to the law in Mexico]. The plant has powerful exhilarating, and afterwards narcotic, properties, similar to those of Indian Hemp or Hashish, in this case due to three alkaloids, viz.: mescaline, lophophorine and anhalonine. The term mescal means a mushroom, and the dried tops of the plant strung into chaplets or garlands, used to be sold as mescal in the Mexican markets, and as botanical travellers were in search of a fungus and not of a Cactus, it was a long time before it was ascertained that the so-called mescal buttons were the dried tops of this Cactus.”

In an intriguing early mention of peyote; Sahagun describes it as being white and produced in the North. This is usually taken to mean a misidentification of peyote with the sacred mushroom. [Which, actually, also are not white, most early writers referred to them as tawny. Sahagun actually described the mushrooms as being black in the 16th century. I wonder, however, if perhaps, the description of the peyote as white is more in reference to the color of the Peyote, itself. When it manifests itself, it is frequently accompanied by the presence of pure brilliant white light Despite having no proof I have to wonder if this might have been what the Aztec informants of the Spaniards were referring to. [Alternately, it could have just been in reference to the prominent white tufts on the dry cactus as opposed to the often dark dried mushrooms. Most commercially produced Psilocybin mushrooms today are not dark.) I similarly once found myself describing the difference between mushrooms and peyote; as the mushrooms being small, dark, warm and colorful and the peyote as being very large and bright white (and also colorful). Another more easily noticeable difference is that the colors and patterns of the phosphenes perceived with peyote have a background matrix of a pure rosy glow. (In contrast to the background matrix of deep purple I observe with mushrooms.)

Note 13: Martin et al 1971 also made the odd claims that early explorers thought dried buttons were fungi and that Mescal is “the word for fungus”. I can not substantiate either point as the Spanish chroniclers clearly mentioned peyote and the sacred mushrooms as completely distinct entities (peyote was referred to as a root; the Psilocybe mushroom as a fungus) and exhibited absolutely no confusion about the two. The confusion in print appears to have begun with William Safford somewhere around the beginning of the 20th century. Martin may have drawn this from Borg but the source for his claim was not made clear.

  Martin also commented that mescaline “is said to increase color perception, if it does not make one too disgustingly sick to be aware of anything!” […] “the Indians do not just sit around chewing the dried buttons in a mass orgy. They go through a series of fasts and taboos that would discourage even the most ardent seeker of sensations.

One would suppose, if all of that was really believed to be true, that Martin would have much fewer concerns about peyote use and abuse?

Note 14: Rätsch 1998 presents white mule as meaning fat- or thick- headed but does not include his reasoning which really should be questioned.

Note 15: Some years ago, a ranger at Enchanted Rock (a batholith) insisted that Mammillaria heyderii did not and could not exist at the park because neither they nor the expert who was completing a native plant survey were aware of them (the absence of this species from their list was the sole reason this subject was mentioned to them).

In more recent years it was noticed and added to their plant list, although their botanist assigned the wrong ID and has inexplicably identified it as the Mexican species Mammillaria gummifera. Which would prove to be a very significant extension of its known range if true. An intriguing claim (in that same report) of a range extension for M. prolifera is at the very least tempered by their botanist’s identification of Opuntia imbricata as O. tunicata.

Mammillaria heyderi in habitat at Enchanted Rock

Mammillaria heyderi in habitat at Enchanted Rock

Note 16: Some may not think of this as a substantial source of loss unless they visited south Texas several decades ago and saw the huge stinking piles of Mexican plants which were stripped from the desert by the truckload simply because they were cacti. Large areas of the Mexican deserts were nearly denuded of cacti except for Opuntia.

Note 17: This is a commonly held, but erroneous, point of confusion. In Texas, this is correctly known as Acacia rigidula.

Acacia rigidula in Jim Hogg County

Lophophora williamsii growing with Acacia rigidula in Jim Hogg County

True Acacia amentacea is restricted to southwestern Mexico. (See Correll & Johnson 1970 for more details.)

Acacia rigidula is abundant in the Texas’ peyotelands, also Chihuahua, Coahuila, Jalisco, Nuevo León, San Luis Potosí & Tamaulipas, in Mexico. It also occurs more rarely in trans-Pecos Texas westward to Brewster County. That combined area also contains the vast majority of peyote’s natural range. Interestingly, Acacia rigidula was purported to contain mescaline and a number of other cactus alkaloids in its aerial parts although the validity of those findings has been challenged. (See Clement et al. 1998).

With results very much in a line with reports of earlier workers such as Adams and Camp, Pawar reported a resounding failure replicate any of their novel  claims.

Sasha Shulgin had also commented to me that despite their assertion of obtaining their reference standards from commercial sources, a goodly number of them are not available through any commercial source and at least one of their novel compounds has never even had a synthesis published.  Efforts of a correspondent to learn more from her coauthor Forbes was told that there was no awareness of any controvery and all molecules were identified using a published compendium of spectral data. (I’d suggest that comment might be disingenuous or at least I would invite readers to read what is actually said in the report of Clement concerning how they made their identifications.) Very clearly any and all of the novel compounds reported in Clement’s two papers presently are in need of proof that they actually exist in those Acacia species.

Note 18: They are easily removed and rooted once their roots start forming. Before this time there will be a fairly high mortality rate if removed while small. If one is patient enough to let them get to over an inch in diameter the survival rates will be quite high even on unrooted cuttings.

Lophophora-williamsii-cut-for-grafting

Lophophora williamsii cut for grafting in a commercial greenhouse.
This cutting would root just fine.

Note 19: Etiolation in peyote causes formation of a rounded spike of the inner most areoles. They can grow to over an inch in height in a matter of weeks.

The color of the projecting, mostly hairless, tubercles starts out as bright pale green (the body still being blue-green), then turning yellow along the furrows, going to yellow with white furrows, and eventually becoming nearly pure white before the rest of the plant (by now pale green) dries up and dies. This is an important survival mechanism for these plants.

Since they are low growing, in winter or in bad weather, they sometimes become partially or entirely covered by blown or washed soil. This rapid elongation enables them to get through to the light and resume growth if buried. If one examines the barky rings (formerly the outermost and oldest green tissues) that surround the upper root (on an old plant) they will often find occasional deep indentations indicating the years that the plant had to partially or totally etiolate to unbury itself.

 It would be interesting to see if there was a usable correlation between known weather history of the area of occurrence and the morphology of the barky rings which might provide better estimates on actual age of older plants.

My belief is that they can get extremely old.

Many species of cacti can live for 200 years or more and there is no reason to believe that peyote is any different.

Note 20: Cristate growth, while infrequent, does occur in many plants.

Epithelantha bokei

Epithelantha bokei crest near Terlingua

What has happened is that, either, supposedly, from mechanical injury, or more likely from some other more poorly understood mechanisms, the point of growth at the center top of the plant (the apical meristem) is no longer a point of symmetry, from which all new growth occurs, but rather it has a line (plane) of symmetry from which all growth occurs (fasciation). Cristate plants express it as a wavy line that grows increasingly convoluted rather than staying planar.

cristate Lophophora 'echinata'

Lophophoraechinata‘ crest

 While the predomininant belief is that crests arise from injury, it is a demonstrable fact that, so far, NO ONE has ever been able to *deliberately* create a crest by injuring a cactus.

Many attempts have been made by a decent number of people using everything from knives to acids; all have been resounding failures. There is however a claim in need of a controlled evaluation that damages resulting from high heat induced the appearance of new crest formations.

  On the other hand, monstrose and cristated individuals arise regularly and naturally within any large enough planting of seeds of a single species. They can apparently arise in any cactus species so should be anticipated to exist for all of the known Lophophora species.

  There are areas in the US and Mexico (and thus probably also elsewhere) which are known to hold an unusually high number of cristate plants involving multiple species, genera and/or families of plants. It is actually fairly common for cristation to occur in a given area and to also involve multiple plant species. It is not uncommon to find several specimens with varying degrees of cristate expression concentrated in a small area within a larger population of normal plants.

  There are also major cactus collections that have deliberately acquired a large number of cristate specimens. In those collections there is a far higher than normal appearance of cristation and monstrose growth in *additional species* in their garden suggesting that some type of a pathogenic vector may be involved. Phytoplasms, some of the rusts and a number of organisms are known which could potentially be the causative agents but as far as I can tell that avenue of inquiry has not yet been studied. (It is plausible that the observations of high greenhouse temperatures inducing novel formation might be due to somehow aiding or supporting the process of infection.)

  Those three observations do suggest that there is a more complex explanation underlying cristation than response to simple injury.

 Many crests will not flower. Some such as the monstrose Trichocereus bridgesii have never been reported to flower despite being in cultivation for close to a century. It is common for those that do flower to produce sterile seeds.

Note 21: A frequent criticism of chemotaxonomy concerns its occasional conflict with accepted taxonomic classification based on morphology. Granted there can be wide variations in chemical profiles for many reasons but we believe chemotaxonomy needs to be incorporated more widely in modern day classifications of plants. Alkaloids expressed, or at least those which are potentially capable of being expressed, mirror the available enzyme systems within a plant and thus its genetic makeup at least as well as morphological expression. (It must be remembered that presence of a gene does not always mean it is expressed.) Rather than attack chemotaxonomy as variable based on environment and available nutrients perhaps we should study those variables more closely to determine and define what ranges of expression are available. (It is far less common for the variability to be qualitative than quantitative.) A good example of the need for and potential usefulness of such clarifications will be seen below in Hortus’ assessment of Pereskia grandifolia being synonymous with Pereskia grandiflora. These were shown by Doetsch to have markedly different chemical profiles.

  Such marked chemical differences at the very least demonstrate substantially different genetic expression. It certainly can serve as a powerful tool to add to our repertoire of plant classification. It should not be perceived as a threat intended to replace the current system. In the case of chemotaxonomic profiles of Acacia seeds, considerable support was shown for the major divisions previously established for the genus. (See Quereshi et al. 1977 and Evans et al. 1977.)

Note 22: Reflect on the contained observation that Peyote plants, collected from the wild in the late 19th century, have been reported that were 63 times stronger than other peyote plants, cultivated and well watered.

Note 23: Todd 1969 presented an interesting tlc assessment of two distinct populations of L. williamsii.

His Coahuilan specimens were far more potent than those collected in San Luis Potosí lending support to the claim that the Coahuilan populations are a higher alkaloid form, referred to by many of us as L. williamsii var. echinata.

Note 24: Varietal name rejected by most authorities as being a multi-headed form that normal growth can take. See Anderson or Benson.

Notes 25 & 26: They apparently named one of their new compounds, Peyotine. Shulgin & Shulgin 1997 have pointed out that this is certain to cause confusion at some point down the road due to its prior use for another compound entirely.

Note 27: Varietal name rejected by most authorities. See discussion earlier.

Note 28: Varietal name rejected by most authorities as being a 5-ribbed form that normal growth can take. See Anderson or Benson.

Note 29: This is the normal form. It is included here for comparative purposes. It would be better if this was referred to as L. williamsii var. williamsii rather than var. typica

Note 30: Thomas N. Campbell 1958, who, according to Stewart, found many archeological stashes of the red bean but only two of peyote.

  Other finds of peyote were also actually noted in Campbell 1958 but a number lacked adequate collection or stratigraphic data.

  He cited Campbell 1947, Martin 1933 & Taylor 1956.

Note 31: Mescaline can be used as a snuff but is very unpleasant both on account of the intensity and extent of the initial burning and also for its taste as it finds its way down the back of the throat. All of these features are very pronounced due to the substantial quantity of mescaline that is required as a dose.

Note 33: See page 32, in Alan R. Sawyer 1975, showing painted figures on a Moche IV culture vessel from the north coast of Peru, ca. 500 AD. in the Kehl and Nena Markley Collection. 

Note 34: On page 89 of Dobkin de Rios’ 1982 article Plant Hallucinogens, Sexuality and Shamanism in the Ceramic Art of Ancient Peru, a winged anthropomorphic long beaked bird [hummingbird?] is unmistakably using a stirrup vessel to administer an enema to a man engaged in intercourse with a woman. [Also Dobkin de Rios 1990: 103.]

 Hildegard Delgado Pang 1992: page 242, also shows three different versions of what in Dobkin de Rios 1982 & 1990 appears to be an enema administration.

 In Pang, this route of application is not clear nor even is the use of a stirrup vessel.

 Dobkin de Rios took her drawing after Elizabeth Benson 1972, where, on page 133-134, fig. 6-7, a drawing made from a relief pot distinctly portrays a stirrup vessel being used for administration of an enema. (As in Dobkin de Rios, there is a second stirrup vessel in the air just above the upper part of the face of the woman, appearing perched on her nose.) It may be noteworthy that the frame of the tambo (an open air ceremonial structure) is contiguous with the headpiece of the man being given an enema. Also notice  the tail-like snake-headed image that seems to be leaving the site of the enema administration, we will be seeing more of those. 

Benson-1972-enema-scene

Possible enema adminstration scene. Benson 1972

 Pang’s drawings came from Christopher B. Donnan 1976 (fig. 1) who uses them to demonstrate how similar the scenes from three different vessels are in content in spite of wide variations of detail individually. [The Jaguar/San Pedro stirrup vessel is also shown to exist as multiple copies in several different versions.]

I do not intend to imply that all such vessels were intended for enema use. Clearly many were not, based on their size, shapes and proportions.

 Ralph E. Cané 1988 also mentions that enema administration may be depicted in Mocha ceramics. He refers to Federico Kauffmann Doig 1979 who refers to the piece just mentioned.]

 On page 505 of Rätsch 1998 there is a drawing of “Ein mythisches Schneckenwesen” with a drawing of a cactus presented to be a Trichocereus. The growth habit of the depicted plant more closely resembles Opuntia or some columnar species other than Trichocereus but it is impossible to declare any genera with certainty. (Noncactaceous plants also appear in the image.)

Schnecken_thing_Ratsch

Schnecken creature from Raetsch 1998

Ostolaza interprets this creature as an iguana; and shows an example of it depicted with spiny columnar cacti.

jug image from Carlos Ostolaza

from Ostolaza

This supernatural creature, or a similar one, can also be found on a stirrup vessel, depicted in a context that suggests enema administration, in Donnan & Mackey 1978: page 69. 

This latter image is accompanied by small drawings suggestive of cacti. They closely resemble the general forms commonly assumed by T. bridgesii & some of peruvianoids in southern Peru; especially when they were previously used for harvesting branches. 

Donnan and Mackey 1978

Donnan and Mackey 1978

 

As with the piece mentioned above with the copulating couple, what may represent the enema exiting the body of the creature are depicted as a serpent-headed “tail” (and in this case are also coming out of the end of short funnel-like objects, *and* the being that is holding said ‘funnels’, in hand).

There are persistent elements that are interestingly repeated in this image of a Moche ceramic. 

"Mochica feline 2" by Simon Burchell - Own work. Licensed under CC BY-SA 3.0 via Wikimedia Commons - http://commons.wikimedia.org/wiki/File:Mochica_feline_2.jpg#mediaviewer/File:Mochica_feline_2.jpg

“Mochica feline 2” by Simon Burchell – Own work. Licensed under CC BY-SA 3.0 via Wikimedia Commons – http://commons.wikimedia.org/wiki/File:Mochica_feline_2.jpg#mediaviewer/File:Mochica_feline_2.jpg

In Dobkin de Rios 1990, on page 102 there is another interesting stirrup vessel portraying what appear to be Opuntias, while on page 105 she shows a photograph of a jug depicting a man with a absurdly large penis through which the contents of the jug can flow.
Another such vessel is shown in Benson 1972. Dobkin de Rios notes that a series of holes placed around the mouth of the jug create a “dribble-glass” effect that make it impossible to drink from without getting wet — unless drinking is done through the penis itself. She has suggested that this ‘drinking’ might indicate symbolic fellatio (which is also occasionally depicted in their art, sometimes the depictions of oral sex involves cadavers).
I have to wonder if it was not intended for another purpose.
A wealth of images of these artifacts can be found in Google images using the search phrases “Moche ceramics” and “stirrup vessel”.

 [It is curious that the Tukwano of the Northwestern Amazon refer to Virola resin and the snuff prepared from it as semen of the sun and the containers used to store it as the penis of the sun. See Schultes & Hofmann 1992]

This image of a deific copulation (from Kaufmann-Doig) was taken from a relief on a Pativilca container (Tiahuanaco-Huari) and shows attendant symbolism commonly interpreted as the Anadenanthera seeds which were used by that culture.

This interesting drawing said to depict the Tiahuanaco-Huari view of creation.
Doig-creation

 Depictions of the dead, with sexual organs and themes, are fairly common in Mochica art.
In one fascinating example of a stirrup vessel [fig. 6-6 in Benson 1972], there is a three dimensional rendering of an obviously dead couple on top of it. The man has one hand holding panpipes and the other around the woman in a tender embrace. There is a painted scene below them of skeletons in a field of wide spouted jugs with abundant stirrup vessels between them. A long flared ornamentation curving downward from the lower back side of each of the happy skeletons could easily be interpreted as defecation of a liquid. As ‘the ancestors’ (i.e. the dead that one is related to) figure widely in the hallucinogen using cultures, we cannot help but wonder if this use of these plants and the frequent depiction of the dead, was not done in their honor.

 Considering that plants such as San Pedro were, and still are, used for such purposes as the healing of disease, blessing of crops and fishing expeditions, and effecting or combating ‘love magic”, and that similar scenes are repeatedly depicted on multiple vessels, perhaps their symbolism is related to what the intended purpose of ingestion was. There is a lot to suggest that what was represented was related to what the intended use was to be.

 Many authors have pointed out that numerous recognizable diseases are portrayed in a good number of these vessels and some are modeled after specific parts of the body such as feet. (Some claim this indicated a fascination and preoccupation with disease.) Certainly, having such clear depictions around while in a tripping state would enhance and solidify both intent and focus. [Symbolic focal points of intent still figure heavily into the use and power of the mesa.]

 For some excellent examples of diseases being depicted in such ceramic art accompanied by photographs of people who are clearly afflicted by the same diseases; see Raoul D’Harcourt 1939. (He also includes a quite clear and unmistakable example of fellatio; the act of which can also be found depicted in multiple Google images of Moche artifacts.)

 Obviously this is pure conjecture as we cannot know what went on in their minds. It is significant that many of these jugs existed in multiple instances and versions. Similar copies were easily made as the vessels were constructed from parts formed in molds. Clearly, many of their designs are not simply arbitrary decorations and need to be considered as significant. Certain themes are recurrent, duplicated on different vessels and persist through long periods of time spanning several cultures.

This persistence of reproduced images and the fact that such vessels were duplicated in molds suggests a thriving market in prepared drug solutions. If this was the case, such images could have served as a simple means of labeling & identifying the contents, or even intended applications, to an illiterate society.

 On page 106, Dobkin de Rios 1984 mentions that copulation between animals is sometimes depicted and that around 20% of these examples involve toads. Curiously, in the depiction of the enema administration, mentioned above, what looks like an anthropomorphized toad stands nearby, facing the copulating couple. (Benson calls it a ‘lizard helper’, and in two of Donnan’s multiple representations it does look more lizard-like.)

 [Benson 1972 shows an interesting example of what appears to be a jaguar, or else a toad with pronounced jaguar features, having sex with a toad. Another portrayal of a toad/jaguar relationship has been unearthed during the excavations at Cacaxtla in central Mexico. A toad, wearing a jaguar skin, grasping what is said to be a ‘venus symbol’, is depicted in one of the murals at the Red Temple’s entrance. See Stuart 1992, p. 136, for a color photo.]

On page 84 of Dobkin de Rios 1982 there is a picture of a stirrup vessel showing a man and a woman clearly engaged in anal intercourse near what looks curiously like Anadenanthera seed pods. She points out (1982 & 1990) that wilka (vilca) was a major drug plant of the Ayacucho highlands region to the east of the Nazca culture and easily accessible as numerous economic plants were traded. It also might be noteworthy that large stands of Anadenanthera peregrina still exist in northern Peru and southern Ecuador and some also contain abundant populations of Trichocereus pachanoi.

 Heterosexual sodomy is far more frequently encountered than actual sexual intercourse on the ceramic art that has been found to date.

Due to many European cultures’ general revulsion for even considering such acts openly, when heterosexual sodomy was encountered as a prevalent sexual act by the 17th century Spanish invaders, their horrified priests were instructed by Rome to extirpate such “ungodly” practices.

 It should be added that the sexual themed Peruvian ceramics have always been very popular and highly sought after by some groups of art collectors and hence much grave robbing/looting, thefts at all levels, black-market sales and private pieces hidden from view or public knowledge has accompanied their removal from the earth and hampered any true assessment of what actually exists.

 It has been proposed that sodomy and fellatio were practiced as forms of population control within a flourishing society living within very real environmental limitations.

Administration of substances by enema was not limited to Peru. In Safford’s 1916 work on parica snuff (usually derived from Anadenanthera spp. seeds) he mentions the use of rubber syringes, described by De la Condamine in 1749, as being used by the Omagua to administer similar ritual substances preceding “the repasts of ceremony” and mentions other travelers reported that extracts thought to be from the same seeds were also administered as enemas by other people. (Such as Spix & Martius 1831 mentioned earlier.) This route was said to be less powerful than when used as a snuff.

The extremely dangerous (and easily fatal) use of a tobacco enema has also been recorded.

San Pedro or peyote are readily utilizable when taken as a retention enema. It has been reported that salt forms are more readily absorbed than crude plant extracts. Case et al. 2004.

Note 35: The upper LH corner image in fig. 39, marker #1625.

Note 36: Another point of possible importance is that, while mescaline has not been reported from Tephrocacti yet, nor for that matter from most Opuntias which have been analyzed, the small jointed species of Opuntias (called Tephrocacti for the South American species) have generally shown the highest levels of alkaloid content observed among the Opuntias.

Note 37: Lyman Benson mentions that this claim is in dispute but included no details.

Note 38: This is often given as Opuntia basilaria. I have not seen Engelmann & Bigelow. I used the spelling as given by Lyman Benson 1982.

Note 39: Some may be light brown or tan on some joints.

Note 40: “Provoca sueños profundos”

Note 41: Oddly, when Clement et al. 1998 identified mescaline in “leaves, petioles and tender stems” of Acacia rigidula, it was said to be accompanied by N-methyl and N,N-dimethyl-mescaline, amphetamine, methamphetamine & N,N-dimethlyamphetamine, additionally many other N-methylated phenethylamines & tryptamines (including DMT) and also β-Methoxy-3,4-dihydroxy-5-methoxyphenthylamine but strangely NOT β-Hydroxymescaline.

It was additionally said to contain a number of never-before-seen-in-nature alkaloids including a total of 6 different amphetamines & 3,4,5-Trihydroxyphenethylamine.

Perhaps most noteworthy is the significant fact that no one has been able to replicate their claims.

Note 42: Thomas MacDougall & Faustino Miranda’s generic assignment was also given as a provisional name.

See Miranda 1954: pp. 139-140

Also encountered as Escontria gaumeri but I can locate no describer or description under this binomial.

Note 43: tlc, was still in its infancy and was not yet considered a standard analytical tool.

gc-ms, as we know it today, did not yet exist.

Opuntia pachypus

Opuntia-pachypus-tip

Opuntia pachypus

Now accepted as Austrocylindropuntia pachypus (K.Schumann) Backeberg.

As Opuntia pachipus [sic], this Peruvian plant was purported to contain mescaline, by A. Caycho Jimenez 1977 (on page 91). His statement lacked any details or a meaningful reference.

Due to the inclusion of other names on his list that are unmistakeable errors, this claim seems best regarded as dubious pending supportive evidence.

 

 

Occurrence of Lophophora williamsii

Occurrence and distribution

From 50 meters in Texas to nearly 1850 m in the state of San Luis Potosí.
Anderson 1980; occurrences along the Rio Grande near Reynosa, Taumaulipas are less than 50 m while occurrences in San Luis Potosí exceed 1800 m Anderson 1969; Below 3000 ft (1,000 m) usually. Lamb & Lamb 1974; At 150-1200 ft (50-400 m) Benson 1982 

Peyote grows isolated or in groups. It can occur as very dense populations, sometimes including large clumps, or be widely scattered as individuals. It is found in calcareous deserts or subdeserts, on rocky slopes of low hills, ridges, alluvial fans or in dried river beds.

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east of Rio Grande City in Starr County
Lines showing this white mottling continue to do so in horticulture.

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Soil surface in Jim Hogg County

Often they are found in limestone, flaky limestone or partly limestone soils; on slopes of small hills, especially if overlying rocks are caliche. Also, found in gravel or stony soils. Morgan 1983 found populations to be more abundant on east and south facing slopes.

Peyote occurs in many soil types. These are typically limestone soils or contain limestone, and may be rocky or even gravely. Soil types in Texas are discussed by Morgan 1983: “All tend towards upland shallow to moderately deep, calcareous, clayey loams.” LaBarre notes that in the northern portion of its range it occurs in primarily calcareous and argillaceous soils of the Cretaceous formations.

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Soil in Presidio County

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Soil in Terrell County

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Soil in Presidio County

Widely distributed in Chihuahuan Desert and Tamaulipan Brushland of the Rio Grande Plain, of Texas, also south of Shafter, and, prior to its damming, at the mouth of the Pecos River, and from Laredo southeastward to McAllen. (Almost to Brownsville according to Anderson 1995 but this refers to a photo in Britton & Rose that is a certain error. Peyote has never occurred “near” Brownsville as both the soil and the terrain is wrong.)

In Texas; originally near the Rio Grande from highly localized spots in Presidio through Starr Counties, historically occurring as far south as the edge of far western Hildago Co although that area has been so intensively agriculturalized it is hard to imagine there are *any* populations left anywhere in Hidalgo County. They have seemingly been reported near Brownsville but this is surely in error. (See fig. 97, page 84 in Britton & Rose 1922 who probably chose Brownsville simply as their closest known landmark), and eastward into parts of Jim Hogg Co. It was once so abundant in Starr  and Jim Hogg county that portion of the Bordas Escarpment has been referred to as The Peyote Gardens (leading some authors to assume cultivation occurred there). The vast majority of that land has been cleared at least once so peyote is now gone.
The featured image at the top of the page shows a view across the Bordas Escarpment AKA the “Bordas Scarp”. The image below was taken on the Bordas Scarp looking west across an area of prime peyote habitat.

L-williamsii-habitat-JimHoggCounty-largeview

Habitat in Jim Hogg County

Habitat in Jim Hogg County

Habitat in Jim Hogg County

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Soil in Jim Hogg County

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Soil in Jim Hogg County

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Soil in Jim Hogg County

 

Plants have been reported or claimed from Brewster, Cameron, Crocket, Culberson, Dimmit, Hudspeth, Jeff Davis, Jim Hogg, Kinney, Maverick, eastern Medina, Pecos, Presidio, Terrell, Tom Green, Starr, Sutton, Uvalde, Val Verde, Ward, Webb, Winkler, Zapata, and Zavala counties. Its historical presence in all of those counties spans the range from certain through doubful to implausible. 

Most of the remaining populations are in Starr, Jim Hogg, Webb & Zapata Counties. Several other counties still have small and scattered populations, while the rest are certain to be errors or may have once held populations that have been extirpated. While plants may have been reported from those areas in the past, its actual range of occurrence is now far smaller.

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soil in Starr County (notice the nearby crust communities)

soil-StarrCounty

Soil in Starr County (again notice the presence of a crust community)

In Texas, its highest concentrations seem to be contained within a narrow band no more than 30 to 40 miles from the Rio Grande.

The vast majority of its native habitat in Texas has been destroyed by root plowing and land conversion for agriculture and pasturage. It has been considered an endangered member of Texas flora by the Texas Organization of Endangered Species (TOES) since the late 1970’s for this reason despite not being categorized as an endangered species at the federal level.

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Sheltered by palo verde in Starr County

According to Morgan 1983; it is most common in Texas along the western margins of the Bordas Escarpment, the Aguilares Plain and in the Breaks of the Rio Grande.

Occurrences along the Pecos River (an area of numerous fine examples of shamanic rock art) are in many case gone due to the formation of Amistad Reservoir. Even if populations survived above the water line, it might be wondered just how well peyote would adapt to being a lake-side plant. Schultes & Hofmann 1992 note peyote remains found in this region’s rock shelters and dry caves show its use to be present for 3000 years or more.   Weniger commented on not being able to locate it growing there in 1970.

It has been reported at scattered locations throughout Trans-Pecos Texas.  The few populations I am aware of are all small and sharply defined. A site may contain its entire population within a zone that is no more than 30 feet by 200 feet.

Some of the occurrences in the TransPecos have been the results of deliberate plantings by indigenous people including one planting that was done in volcanic ash rather than limestone. Interestingly the mineral content and pH was not too far off from a limestone soil and what few plants survived have managed to produce a few successful seedlings. A collector gathering a couple of dozen plants would entirely wipe out the entire tiny population. Around half of the known plants at that site were in fact lost when someone collected them within just the last several years.

Plants have been claimed from as far north as New Mexico, south of Capitan Mountain, but this commonly experiences the lowermost limits of their winter temperature tolerance so it is doubtful that any populations exist in either New Mexico or in the northern part of Trans-Pecos Texas. In the US, Weston LaBarre considers Deming, New Mexico to be its northern limit (!?) and Corpus Christi to be its southern limit (!?). Both of which are not realistic to believe. In Texas, peyote has been reported from as far west as Hueco Tanks where those plants, now long gone, were believed to have been planted by indigenous people.
Occurrences have also been claimed in the Davis and Guadalupe Mountains which seem to also have climates that would challenge any of the known populations.

I think (as do a number of others) that climatic changes may have substantially reduced peyote’s natural range from where it once was and that the sporadic northern populations in Trans-Pecos Texas are hardy remnants of this earlier distribution.  It is also probable that postglacial megaflood events shaping the landscape played a role in removing both entire populations of plants and their natural habitat.  Much of that gravel interestingly enough ended up in South Texas creating a home for many of the present day Lophophora populations. One element which is easily overlooked is that not only did west Texas see massive land removal during the post-glacial meltings but prior to that during the last period of glaciation West Texas was relatively mild (certainly not any worse than it has been after the end of glaciation) and had more moisture due to the influence of the ice masses on air currents in North America. (See the youtube video Keeper Trout 2011 Lophophora A genus in Decline and a forthcoming book chapter in Labate & Cavner 2015 Peyote & People, for more details of the above facts and speculations.] 

Some such as Hueco Tanks, extirpated in historical times, and in Big Bend, known to consist of only a very few plants, likely were the hardy survivors of plantings made by the ranging peoples who regularly moved through the area or perhaps by the Jumano who farmed many crops in West Texas and had extensive trade networks with their neighbors — at least prior to the arrival of the Apache. A friend in Midland successfully grows peyote in an unprotected outdoor garden and has seen them covered with snow several times with only small losses.

However, in any population of slow growing plants, even small losses, if recurrent, may completely wipe them out of an area over a period of many years. Stresses like injury from harvest greatly increase the threat of death from cold and wet or prolonged drought.

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Soil and stressed plants in Presidio County

cold-stressed

A closer view of that cold-stressed plant

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Soil in Presidio County

Anderson dismissed ALL of the northernmost reports of occurrence.

It should be emphasized that, like Anderson, Stewart 1987 disputed ALL extensions of distribution beyond those given by Anderson, basing this on his inability to find any demonstrable evidence of peyote’s occurrence in those regions.

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Habitat in Val Verde County

Stewart is largely right (with some exceptions) but he heavily based his opinion on landowner’s responses to questionnaires and interviews with peyoteros. [Note 15]  Field work has shown his conclusion to be premature but understandable. Its easy to imagine many ranchers and landowners could own property all of their life and never have reason or opportunity to see what few and scattered groups of a few plants might be on that land.

It actually is certain that Stewart is largely right but that he is partially wrong if making that as a blanket statement. A feature that probably contributes with the Trans-Pecos populations is what was just noted: they are small in size and widely scattered. This seemingly grows more true as one goes farther north but I do not know the issue has been studied in depth by anyone. It has been the case in the only two northernmost ones I have seen that their entire populations was contained within an area that of only 10-20 meters by 75-150 meters.  One in Val Verde County was at the lower end of that and one in Terrell County was on the upper end of that. The one in Val Verde might not have contained enough plants for more than a single modern peyote meeting. Relatively small areas containing any density of plants seem to be the norm even farther south in West Texas.

Lophophora comingling with lechuguilla and candelilla

habitat in Presidio County

One possible contributing factor to Stewart’s questionaire not producing better results is the simple fact that many landowners would not WANT anyone to know there is peyote on their land even if they knew about it. In that case there would have had no problem not cooperating with Stewart’s inquiries. Choosing to avoid potential problems due to going “on the map” for having a peyote population is a reasonable response. There is no doubt actual wisdom in that as contributing to there being an accurate map of peyote distribution would serve little purpose outside of perhaps enabling more harm to be done to peyote populations.

Wirikuta-d-Hjeran

Wirikuta. Photo by Hjeran

They are widely distributed throughout the central highlands of northwestern Mexico and extend southward from the border in a broad area across the basin regions between the Sierra Madre Occidental and the Sierra Madre Oriental, extending south until just south of Saltillo where the range is narrowed by mountains.

It then expands again west into part of Zacatecas and eastward into the foothills of the Sierra Madre Oriental, into central Mexico as far south as north of San Luís Potosí. The range is separated from the more southerly high desert L. diffusa by rugged mountains.

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Lophophora williamsii habitat at Wirikuta. Photo by Hjeran

LaBarre describes its range in Mexico as being defined by the Tamaulipecan Mountains in the east, “the watershed of the affluents of the right bank of the Rio Grande de Santiago and the Rio de Mezquital” in the south and “the foothills of the Sierra Madre, the Sierra de Durango and the Sierra del Nayarit” in the west.

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soil at Wirikuta. Photo by Hjeran

In Mexico, scattered populations have been found in Aguas Calientes (proposed to have been established through wildcrafting by the Aztecs), Chihuahua, Coahuila, Durango, Hildago, Jalisco, Nuévo Léon, Querétaro (according to some; this is likely mistaken), San Luis Potosí, Sonora (according to Rouhier), Tamaulipas and northeastern Zacatecas. Possibly the most famous area is in the Real del Catorce, below the once thriving silver mining town of Catorce. Another reknown ancient collection site is the Cerro de Peotillos near San Luis Potosí.

Bohata et al. 2005: “Typically, the centre of distribution is the place of greatest plant density for the species. This centre for L. williamsii is in the northern part of the state of San Luís Potosí, the south-western part of Nuevo León, and the south-eastern part of Coahuila.”

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soil at Wirikuta. Photo by Hjeran

[Anonymous 1959, on page 22, includes Sonora. They cite as their source, Rouhier 1926 who they state drew his information from a pamphlet published in 1913 by the Instituto Médico Nacional de México. This is an implausible location but suggests a possibility of confusion with some other plant held sacred by local people?]

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Lophophora williamsii at Wirikuta. Photo by Hjeran

While populations have been decimated in many areas of Mexico from habitat loss or harvests [for ornamental purposes [Note 16], sacramental use, mescaline manufacture and also for mass destruction in petroleum distillate soaked burnings as a perceived evil threat against the Christian faith], there are still many remote and rugged areas in Mexico. These generally have poor, and often no, road access and should hold good reservoirs to ensure peyote’s survival as a species regardless of the pressures which humans have placed upon it. In my thought, the survival of the species is more important than anyone’s access to it.

The best treatment of the subject I have yet seen in print and one I would recommend reading is the Bohata et al 2005 Kaktusy Special Lophophora issue.
The above was written primarily long before its publication and would no doubt never have been written had it appeared a few years earlier. It incorporates a really impressive view of the genus Lophophora in its home.

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Lophophora williamsii habitat amidst Larrea at Wirikuta. Photo by Hjeran

 

Distribution and occurrence comments were adapted from:

Anderson 1980 & 1995

Benson 1982: 683

Morgan 1983

LaBarre 1989

Lamb & Lamb 1974

Schultes 1937a

Schultes & Hofmann 1980

Personal observations and discussions with peyote collectors.

See also:

Morgan & Stewart 1984 for a fascinating history of peyote harvesting in Texas.

 

archaic peyote, some beans & a rock

Archaic points of potential interest

See page 194 in Schultes & Hofmann 1980 concerning the claims of Adavasio & Fry 1976 related to archeological finds of peyote in rock shelters and caves in the Cuatro Cienegas Basin in Coahuila, Mexico. 
This is a fascinating article that is often mentioned in conjunction with their proposal that, over the millennia, sacramental plants were progressively replaced by safer ones. While it is a tantalizing notion to entertain, it needs to be understood that Adavasio & Fry did not include adequate evidence to support either of their assertions; a) that the use of Ungnadia preceeded that of Sophora and b) both were eventually replaced with Lophophora.
Three points need to be made:

First, any evidence presented for the sacramental use of the Mexican Buckeye (Ungnadia speciosa Endl.) is circumstantial at best, being primarily based on its form of packaging being similar to that of the Texas mountain-laurel (Sophora secundiflora (Ort.) Lag. ex SD), their occasional co-mingling, and was bolstered with only one lonely second-hand detailless reference suggesting it to be a euphoric plant. There does not appear to be any accounts of or archaeological evidence for it actually being used for human ingestion ceremonially. And there are no other comments from anywhere else, before or after, that this toxic material has ever been used by anyone as a euphoriant. This is not a small point to overlook since people reading such accounts often include reckless bioassayists.

Ungnadia speciosa leaves

Ungnadia speciosa leaves

Ungnadia speciosa flowers

Ungnadia speciosa flowers

archaic: Ungnadia speciosa seeds

Ungnadia speciosa seeds (seed pods are the ‘featured image’)

Second, Sophora itself is not known to have ever actually been used as a sacramental hallucinogen per se. It was employed in a highly dangerous form of a vision quest to gain animal spirits as guardians, protectors or familiars. Granted, it was incorporated into the peyote drink as prepared by several tribes and it is reasonable to assume that to be an ancient practice. It has been closely associated physically with peyote rites, strung as beads, as well as reported to have been used medicinally, ritually and as a “narcotic” (a word that has been so misapplied, misconstrued and misused anthropologically as to have little, if any, reliably discernible meaning).

Note: The Texas Mountain Laurel AKA Sophora secundiflora saw a nomenclatural revision to Dermatophyllum secundiflora. We are preserving the older name to enable search engines and indexing services to function effectively.  Loss of search engine access to a large portion of the existing published literature is an underappreciated side-effect resulting from the sweeping revisions which are ongoing based on new molecular work.

Sophora secundiflora flowers

Sophora secundiflora

Sophora secundiflora leaves

Sophora secundiflora

I do not dismiss Sophora‘s sacred stature, nor would I want to dispute its long association with the peyote ritual but it is important to keep in mind that its use (or effectiveness) as a hallucinogen has never been adequately demonstrated. It certainly is not supported by any of the published human bioassays involving either the plant or its pure alkaloids. 
Descriptions of its effects were given years ago, in an upper division University of Texas at Austin anthropology class taught by Dr. William W. Newcomb (ANT 322M: “Indians of Texas”). Newcomb presented the stage of interaction with animal spirits to occur while the subject was in a deep coma-like stupor. Their successful entry into this state was said to demonstrated to onlookers by their unresponsiveness to a toothy gar-fish jaw being raked across their flesh. After intense headache, profuse vomiting and violent convulsions, a “coma” ensued that was said to last for several days. [That commentary is not included in his book Indians of Texas but rather was taken directly from my class notes.]

Sophora secundiflora seeds

Sophora secundiflora

Dr. Newcomb clearly presented it as being used ritually but not as a ritual sacrament or hallucinogen in the sense of peyote.
[See Schultes & Hofmann 1980 & 1992 for a broader discussion and also Hatfield et al. 1977 for chemical study and a discussion of the reports of ethnological use. LaBarre 1975 also includes a fascinating discussion.]
Ott 1993 mentions that despite claims by a number of people that the use of the ‘Red bean’ was the predecessor to and replaced by that of peyote, this was thoroughly challenged in a monograph by Merrill 1977.
I only know one person, requesting anonymity, who incredibly decided to see what ingestion of Sophora seeds would do for them. Their comment is noteworthy: “The red beans just made me puke and not much else“. I have never ingested the seeds but have smoked dried Genista canariensis (canary island broom) leaves which are reported to contain the same toxic alkaloid cytisine. It was a pleasant-tasting smoke and had an action that felt very similar to nicotine although it was not as pleasant. I am a former tobacco-smoker and want to remain one so I have no further desire to experiment with this alkaloid.
I have had some very curious interactions with this plant; none of which involved its ingestion. It is definitely able to interact with people, and to a surprising degree to direct and influence their behavior to gather its seeds. I also believe it to be a sentient being based on my experiences with it as a living plant. It is not surprising that it was highly venerated by any people who knew it. It is also not surprising that they would gather its seeds in large numbers and store them in a special context. I’ve noticed that this still occurs although I am guessing modern containers of beans are maintained entirely for their decorative value.

Finally, my main objection to the conclusions of Adavasio & Fry is concerning peyote as they only selectively mention one solitary occurrence of the plant found by an earlier worker [Note 30]. 
It is very peculiar to attempt the support of such important conclusions with a single data point. Perhaps they also encountered additional examples but did not mention the details in this article. It is a puzzling omission considering their core assertion was one of safer plants being sequentially adopted.
Campbell 1958 had flatly asserted that it was not possible to demonstrate the priority of mescal beans over peyote based on the available evidence so something more is required to be able to accept the claims of Adavasio & Fry.

It might also be added that there is a lack of evidence suggesting any continuity of culture in which a sequential series of sacramental replacements *could* occur but this seems trivial by comparison to the three points brought up above.

No futher evidence was presented by Adavasio & Fry.
Disturbingly, the only find of peyote mentioned by Advasio & Fry in the same context as Sophora and Ungnadia was that of ONE string of dried peyote buttons dating from several millennia after peyote is known archeologically to have been employed by humans. 
[See also the comments in Boyd & Dering 1996 concerning Ungnadia.]

The omission by Adovasio & Fry of any reference to additional known archaeological material is puzzling but it is far from being the only instance of cherry-picking that one can encounter in this area.  
Schultes & Hofmann 1992 commented that peyote has been thought to have been in use for at least 4000 years. Dry cave and rock shelter finds in Texas are also said to have yielded dried samples of peyote that were three thousand years old and one find was purportedly dated to 7000 years.  Those refer to specimens in the Witte Museum that have been claimed to be of that immense age (more on this in a moment.)
Oddly, until recently the entirety of the radiocarbon dating surrounding peyote has almost been characterized by missing information. 
Let’s take a look at what is known concerning ancient peyote dating.
There are five reports where peyote was mentioned as being recovered from archaeological sites but material for only two of these can be located within the known collections. (See Terry et al. 2006 for details and references.) 
One of these was from Cuatro Ciénegas, Coahuila, Mexico. This is a burial site from the transition between the Late Archaic and the Late Prehistoric Periods.
The account of Bruhn et al. 1978 gave its age based on Thompson’s dating of a mat thought to be associated with that single set of 8 strung and remarkably well preserved peyote buttons (which interestingly had all been harvested in alignment with modern best-known harvesting practices of carefully taking only the green crown). Three mats had been dated with a range of 810-1070 AD (uncorrected values). 
Due to the burial being a secondary interment, Martin Terry dated one of the actual Cuatro Ciénegas’ peyote specimens establishing its age as 835 ± 35 14C years BP.
Shumla Cave (No. 5, 41VV113) in southwest Texas on the other hand was an inhabited residential site (with intrusion of several burials.) The peyote was believed to have been deposited in the Eagle Nest subperiod of the Middle Archaic Period.
The exact provenience of the materials removed from the caves was not recorded but it is clear that they did mention recovering “a single mummified example” from Shumla Cave No. 5. This later became mistakenly presented as “petrified”. There was clearly more than one such artifact recovered from those excavations as three remained at the Witte for the removal of samples following the consumption of several others for earlier radiocarbon analysis. Terry et al. 2006 also reported their dating of the Shumla Caves’ peyote to 5195 ± 20 14C years BP.

 

Summary of earlier dating accounts:

Peter Furst was the first to report a date of 7000 BP for the Shumla cave material but due to several reasons the actual test data is said to be either lost or irretrievable. It is therefore not possible to know anything further about the work or the claim. That claim oddly only appeared as a passing mention within a book review written by Furst. His date was repeated by Schultes & Hofmann and now appears stated as a fact throughout the literature.
Bruhn et al. 2002 presented a letter to the editor of Lancet in which they asserted establishing peyote use for 5700 years after dating the Shumla material (Furst’s 7000 BP). They repeated the claims in DeSmet  & Bruhn 2003 citing Bruhn et al.  2002 as their primary reference.
El-Seedi et al. 2005 reported dating the Shumla Caves’ material to 3780-3660 BC.
Jan Bruhn  (in a personal communication with Martin Terry) reported this was a weighted mean of 4952 ± 44 14C years.
Further investigation by Terry suggests that the discrepancy was most likely due to a failure of Bruhn to remove residual humic acid prior to radiocarbon dating. (See Terry et al. 2006)

Before leaving the subject of Sophora and Ungnadia completely, one point which must be considered is that world wide people have often venerated plants known to be deadly or exceedingly dangerous, with no intentions of using them for ingestion unless perhaps for the purpose of inducing death, or sometimes when ascertaining the guilt or innocence of a person by ordeal poisoning.
Many other ritual purposes besides hallucinogen use exist for plants. As the authors point out, the quantities found far exceed what would be needed for ingestion purposes. [Issue might be taken with their regarding a “crazed” state as being one conducive to, much less equated with, any ritual or sacred act. If anything it reflects a common culture-centric dismissal of what is viewed by that culture as representing a ‘more primitive’ mindset.] 
The most common usage of the red bean is that of ornamentation in the form of beads. The Mexican Buckeye would also make fine beads although none were mentioned as such. 
Apparently the finds of both seeds consisted primarily of small caches of them, sometimes mixed together, which were sealed in plaited or twilled baskets which had to be torn to access the contents. Both seeds also make a very nice sound, with good high frequency components, when shook or stirred. In quantity; the sound is absolutely mesmerizing. Such containers might have been musical instruments?
In some sites, Sophora seeds and pods were found scattered throughout the cultural deposits. 

Sophora-fruit-1 3

Sophora secundiflora seedpods

Those twilled containers could also represent power objects used just as they were. We know between almost nothing and nothing about these people’s religious and spiritual beliefs. Some people who later used the beans believed they needed to be roasted until yellow, or forcefully struck and crushed, to ‘kill’ them before use. Since the seeds recovered in those finds were apparently being stored intact perhaps they were intended to assure protection after death, or at least to be available after death.
It may be noteworthy however that in the Murrah Cave many of the individual Sophora seeds were described by Holden 1937 as being “parched”; perhaps indicating preparation for potential drug use. Alkaloids can sometimes be altered using heat so parching can be reasonably suspected to indicate preparation for some type of human use.
It is not clear how many of these finds were in funerary context as was the case for the string of peyote and how many were found in residences (suggesting their employment by living people). The context can be complex as it is clear that burials occurred that intruded into older residential remains.
Their hypothesis is intriguing though; further work should be done to evaluate it even if it turns out to be a blind path. 
A systematic review of the contents of rock shelter and cave excavations in the Chihuahuan Desert might prove a valuable avenue for anthropological studies of the religious and spiritual beliefs of people in this area before the invasion and occupation. The creation of small painted rocks and large pictoglyphs featuring shamanic themes are among the unique elements left by the archaic people who once lived around the mouth of the Pecos River.

 

A fascinating analysis was performed, by Bruhn & workers, on the aforementioned specimen of Cuatro Ciénegas peyote (the string of buttons) which was found by Taylor in 1941. 
Bruhn et al. 1978 found 2.25% alkaloid in the Cuatro Ciénegas’ material in spite of it being thought to be from around 810 to 1070 AD. Their analysis was reported to show it to contain mescaline, lophophorine, anhalonine, pellotine and anhalonidine present in measurable amounts.
Phenolic alkaloids formed 35% of the total. It was noted that this is substantially lower than the 8% total alkaloid and 64% phenolic fraction which they observed in recently prepared peyote buttons.
They used tlc and GC (both with known reference samples) to determine this.   See Bruhn et al. 1978 for more details.
A peculiar assessment was more recently presented by Bruhn et al. 2002, also DeSmet & Bruhn 2003 and also El-Seedi et al. 2005 where it was being noted that the total alkaloid content was lower in the far older Witte material from the Shumla Caves. They then went on to assert that while only 2% alkaloid was present there was no alkaloid other than mescaline that was detectable. That was intriguing enough but was not the end.

Bruhn then made the peculiar proposal that the reason they could only detect mescaline could be due to mescaline being more stable than the other peyote alkaloids. Reasonable enough on the surface yet it is noteworthy that in this that Bruhn failed to mention or consider any of his own previous work which contradicts this claim. Clearly something is in need of closer inspection. This claim about the Shumla specimens needs consideration in the light of his 1978 Cuatro Cienegas results. There was also his earlier report concerning degradation of peyote alkaloids in the study of 87 year old peyote buttons published in Bruhn & Holmstedt 1974. In particular, their determination in that paper clearly reported that the mescaline content apparently decreased faster thanhe  trate of decomposition of many of the other alkaloids. The cherry-picked selective presentation of facts within their 2002, 2003 & 2005 accountings appear to have been overlooked by Bruhn’s peer reviewers or at least they dropped the ball in terms of what peer review is meant to accomplish. That is all actually fairly however when trivial compared to what they AND all of Bruhn’s team missed.
The most interesting aspect of this so-called ‘mummified’ material in my mind is that, unlike Bruhn, Furst or Taylor,  Terry & coworkers recognized that the specimens were not dried peyote buttons at all but rather were manufactured effigies of peyote created from some type of doughy material. (See images of both the Shumla and Cuatro Cienegas materials in Terry et al. 2006.)

It seems nothing short of peculiar that all previous workers, despite their apparent familiarity with peyote, somehow failed to recognize that these were human artifacts and not dried plant parts; as they lack all of the anticipated and requisite botanical features that would characterize a dried peyote button.

 

Shumla_Terry_et_al_p1019_fig_3

Shumla peyote effigy

There are only the partial and hollowed out remains of three of these effigies are left due to the destructions of the rest of the materials during chemical analysis and radiocarbon dating. They were formed as a mixture of cactus materials combined with some sort of unidentified fibrous noncactaceous plant material and the resulting dough shaped by hand to vaguely resemble a living peyote cactus top. There was apparently at least two different makers of these artifacts over a period of some years as both their compositions and their dates varied. The most recently manufactured effigy had used entirely cactaceous materials.
More remarkable would be the assertion by Bruhn & coworkers that was just mentioned that this material contained 2% mescaline by weight *and* that only mescaline was detectable. Intriguing if true but in light of Bruhn & Holmsted previously establishing the deterioration of mescaline over time occurred at a faster rate than the deterioration of most of the other alkaloids I am left with far more questions than answers. It is obvious that we need to remain skeptical of Bruhn’s  claim, no matter how intriguing it may be, as we proceed.
One thing that is clear, these ‘buttons’ were clearly manufactured artifacts. To be able to retain 2% mescaline after 5 millennia would require it to have once have had a far higher alkaloid content. The presence of ONLY mescaline would not be a result of some magical selective degradation process omitting mescaline but would absolutely require the involvement of some type of purification process. Or perhaps there are missing elements of this tantalizing puzzle that are presently defeating our understanding of exactly what has been established in these studies. 
Did these prehistoric people really know of a route for purifying or at least greatly concentrating mescaline?  It would certainly be interesting if true but establishing that Bruhn’s analytical results were actually valid has to be the starting point for answering this peculiar question and the burden of proof for establishing their validity is on the authors of that work. 
Were these potent effigies a prepared drug form that were created for sacramental use rather than for simple use as effigies? No matter how they were prepared and no matter what their alkaloid content, they are clearly both deliberate and sophisticated in their preparation.
Are Bruhn/El-Seedi/DeSmet’s reported analytical results simply needing to be questioned? 

 

“Petrified” peyote buttons

The first reference to ‘petrified peyote’ was a misnomer in reference to the Shumla Caves’ adulterated & reconstituted 5 millennia old peyote effigies that were mentioned above. (See Terry et al. 2006 for details.)

More recently ‘petrified peyote buttons’ have been offered for sale (and finding at least one buyer) at a large southwestern Gem & Mineral Show and probably elsewhere.

 
petrified-peyote-front

Sold as petrified peyote button (front)

petrified-peyote-back

Sold as a petrified peyote button (back)

These do appear on first glance to vaguely resemble dried peyote buttons but are without a doubt either an agate or another form of chalcedony with a fine drusy quartz coating on one side. They lack the critical features (such as ribs, the distinctive apex and areoles) that are typically found in peyote buttons (see below).

Schultes 1937 peyote buttons

peyote buttons

  The purported “petrified peyote” are amazing natural treasures but clearly are not of botanical origin.

Lophophora williamsii analysis

Analysis reported for Lophophora williamsii

An interesting objection to peyote cultivation has been raised based on the assertion that peyote in cultivation may not express all of the alkaloids reported from wild plants. Something which was missed in this claim is that the minority of peyote alkaloids have been reported from wild peyote and the majority, including all of the known trace alkaloids, were found using elaborate gc-ms trapping experiments and other approaches intended to capture short-lived intermediates and trace alkaloids. All of those studies used peyote plants which had been grown from seed and cultivated in greenhouses, primarily in northern Europe. rather than wild harvested plants. 

Mescaline content of Peyote

As is true for the alkaloid level of any plant, the mescaline content of peyote exists as a range that is influenced by at least several factors. The following simply summarizes the literature. Only some type of actual analysis or bioassay can say something accurate concerning a plant in front of a viewer. Literature should be viewed with caution and regarded to be only  guidelines suggesting potential values.

“Arthur Heffter, a German pharmacologist of the nineteenth century estimated that there are about 4.6 to 5.8 grams of mescaline in every kilogram of dried peyote.” (Anderson 1980)
Heffter reported a maximum recovery in his work of 6.3% mescaline, 5.3% anhalonidine, 3% anhalonine, 0.5% lophophorine, 5.3% anhalamine.
Späth later reported having much lower yields working with old material.

Mescaline has been reported from L. williamsii with a min and max value of 0.10% and 6.3%. A range of 0.9-6.0% by dry wt is what is generally given.  [Anonymous 1959, Heffter 1896a, Lundström 1971b, Martin & Alexander 1968, McLaughlin & Paul 1967 & Siniscalco 1983);
Anderson 1980 cited Kelsey 1959 (0.9%), Bergman 1971 (1.5%), Fischer 1958 (3%), Heffter 1896a (4.6-5.6 %[-6.3%])

Crosby & McLaughlin 1973 commented that mescaline content in dried peyote can reach 6% but rarely exceeds 1% in dried whole plant.

6% appears in Anderson, Kapadia & Fayez, Lundström 1971b, Martin & Alexander 1968, and Reti 1950. These are all second-hand accounts of that 6% value; referring to its publication by Heffter.

0.1% dry wt is the lowest value in the literature; reported in Siniscalco Gigliano 1983.

  Ott 1993 estimated 2.4-2.7% mescaline by dry weight (~400 mg. per 16 grams of dried cactus) citing Bruhn & Holmstedt 1974 and Lundström 1971b. 

Friends with extraction experience found fresh plants to average 0.2% mescaline from fresh plants and 1-2% from dried material. This refers to peyote originating from South Texas during the mid-1970s. This work was always done under fairly primitive and inefficient conditions. 2% is usually cited as an estimate in counterculture drug manufacturing literature. (50 grams of dried peyote per gram of mescaline recovered.).

Recently, a meme of “1% max” has been circulating; perhaps reflecting the current decrease in the average age and size of harvested plants due to careless overharvesting and harvest practices?

75-125 mg of HCl was recovered from 70-140 gm plants greenhouse grown in northern Europe. Lundström & Agurell 1971b (This approaches 0.1% by fresh weight; ; 0.1 to 0.2% by fresh weight is a commonly reported range.) [Also in Habermann 1978a & 1978b (from Štarha nd)] 

Mescaline has been reported to comprise around 30% of the total alkaloid content of L. williamsii: Lundström 1971b. 

Container grown plants in Italy were reported to contain 0.255% by fresh weight (2.55 mg/gm fresh was an average value derived from two specimens; estimated using HPLC). They also reported an average of 1.75% by dry weight. (Ed.: Note the obvious discrepancy)
Gennaro et al. 1996; 

As L. williamsii var. typica Croizat:
0.709% (± 0.032) dry wt. Habermann 1978a (from Štarha 1997)

Variations across range:

Starr Co.: 2.77%;
Jim Hogg Co: 3.2%;
Val Verde Co: 3.5%;
Presidio Co: 3.52%.
(Averaged % by dry weight:  Used batched samples.
Hulsey et al. 2011.

Regrowth:

3.80% mature crowns,
2.01% small regrowth crowns (4 year after the prior harvest).
(Jim Hogg Co. Averaged % was by dry weight: – Used batched samples.)
Kalam et al. 2012 & 2013.

Batched samples were used to deliberately create an average value and lessen the possible contribution from potential high or low outliers. Comparison of Hulsey with Klein’s paper shows the wisdom in choosing that approach even if it does deprive us of an understanding of the max/min values.  The ideal approach is a screening using batched plants followed by a more detailed look at a set of the individuals.
One peer reviewer suggested that batching in Kalam invalidated their results, which if true would invalidate the results of almost all published analytical work appearing in the history of phytochemistry.

Almost all workers analyze multiple individuals to minimize the influence of potential outliers, the only actual difference between the acceptable approach of those workers (including in the same journal) and what was complained about with Hulsey or Kalam is the earlier workers did not REFER to their batched samples as being a batched sample.

 

Distribution in the peyote plant

Janot claimed to have established that alkaloids were largely produced in the peripheral green parenchyma of the crown. As this was during the 1930s the identification would have been established using microchemical methods. 

Todd 1969 found mescaline in the tops to be substantially greater than in the roots (using co-TLC).  (See Note B) 

Anonymous 1959, citing Rouhier 1927 “Le Peyotl”, gives the following percentages of alkaloid content in different parts of the cactus (% by dry weight unless otherwise stated):
Upper slices dried 3.70%
Lower slices dried 3.43%
[The above refers to the practice sometimes employed of horizontally sectioning the top of the cactus into two parts prior to drying.]

Peyote head dried 3.14%

Fresh peyote head 0.41%
Roots dried 0.73%
Fresh roots 0.244%
Rouhier’s roots would have included both the subterranean stem and the roots.

A closer look using 13 individual plants divided into three parts (crown, stem & root) that were then each analyzed separately:
1.82-5.50% in crown tissue,
0.125-0.376% in subterranean stem tissue,
0.0147-0.0520% in root tissue.
(Starr Co.; Analyzed individually. All % by dry wt.)
Klein et al. 2013 & 2015.
Notice that there is an order of magnitude decrease from crown to stem and again from stem to root? 

 

Growth conditions

Siniscalco Gigliano 1983 reported his isolation of mescaline as:
0.10% from well irrigated plants,
0.93% from his grafted plants, and
up to 2.74% dry weight after 6 months of dry conditions.
All from peyote plants being cultivated in Italy.

Dried plant is said to have 3% Roland Fischer but Fischer claimed that only if chewed well or ground finely can this be extracted. He presented a study as indicating that less than one percent is obtained by chewing and swallowing. While finely grinding or chewing well is important for obtaining the best possible absorption (especially if using dry material) it must be pointed out that Fischer’s reasoning had some problems.
Fischer was able to get 3% mescaline from dried peyote by grinding it to a powder before beginning his extraction procedure. He found that if this dry grinding was omitted and the buttons rehydrated by soaking in water for two hours and then ground before extraction he could only recover 1%. 
He went on to conclude “The only safe conclusion would be that the chewing of peyote and the swallowing as a bolus are certainly less thorough extraction procedures than our “wet grinding” procedure which recovers only about 1% of mescaline.”There several major flaws in Fischer’s reasoning and procedure, in so far as applying it comparatively to humans. 
The more trivial of the two concerns Fischer basifying the buttons after soaking in water and then grinding, filtering, washing and adjusting the pH to 3.4 to 4. 
In the stomach the chewed buttons are repeatedly macerated and massaged by peristaltic contractions in a dilute but fairly strong solution of hydrochloric acid (normally pH 1.5 to 2.5) which converts the rather poorly soluble mescaline base into the exceedingly water soluble mescaline hydrochloride. This means that the acidity used in human in vivo extraction is several orders of magnitude greater than that used by Fischer. (The effects of the digestive enzymes in the stomach do not contribute much as they consist primarily of pepsin which is specific for proteins.)
A more significant point was Fischer’s choice of base. When recovering 3%, he had used sodium hydroxide to bring it to pH 8.6, which is nearing the lower limit for good mescaline extraction as the free base. (97% at pH 8.6 according to Woods et al. 1951; 100% extraction is said to occur at pH 9 or above.). When he recovered 1%, for some reason he had decided to use sodium carbonate instead. This base is a good choice for many alkaloids. (It would have been acceptable if, for example, he was isolating DMT.) His bringing the pH to 8.8 might have enhanced his yield a trivial amount but mescaline has a tendency to form an insoluble carbonate, whether the carbonate source is in air or solution. This may have decreased his yield. [This may also have caused Reti some loss with Trichocereus terscheckii as well. This is just a hunch as rigorous evaluation has not been conducted. I should add that the presence of CO2 is also said to be critical for crystallization of mescaline to occur; according to LaBarre 1989.]
Although in agreement with the idea that chewing well or fine grinding is important to the best absorption, any direct comparisons of his findings to human rates of internal utilization need questioning.
While direct measurements of internal absorbence may not be possible, it would be feasible to administer known dosages of mescaline and subjectively compare them with known amounts of mescaline in cactus material. If a series of such bioassays were performed using experienced users a rough estimation could be determined which would be at least as accurate as Fisher’s extrapolation. It may also be possible to determine the percent of absorbence by monitoring the initial rise in blood levels during the early stages. This also would require the use of pure mescaline to establish a baseline. It also would require repeated evaluations using both different and the same individuals to be certain that biochemical individuality did not affect the results.

There are two additional accounts in the literature that are important to be aware of:

Sasaki et al 2009 and Aragane et al. 2011 published details from an interesting study of Lophophora demonstrating that genetic and chemical differences exist between L. williamsii and L. diffusa.

They additionally included three specimens of L. fricii but apparently renamed it based on what they found in publications by Edward Anderson, by Yoshio Ito & by H. Hirao. Aragane presented it to be a nonmescaline variant of L. williamsii. Earlier, Sasaki had said they had reidentified it as L. williamsii var. decipiens.
It is clear without any doubt that those three specimens were Lophophora fricii

Aragane noted them to differ from their Lophophora williamsii
1) by the word grey appearing only in the descriptions of their body color and not in those of any of their L. williamsii,
2) bearing large protuberences on the epidermis rather than small ones,
3) 2 of the 3 were noted to have a darker pink flower,
4) The primer sets were different from all of their L. williamsii (and closer to what was noted for diffusa),
5) They were purchased identified as Ginkangyoku (which is the Japanese trade name for L. fricii).

I’ll quote from those two papers as their contained comments provide more than adequate support for my line of reasoning:

We identified the materials according to Anderson’s morphological classification.” Sasaki et al 2009.
The pertinent point being that Anderson recognized both Habermann’s Lophophora fricii (and wild plants he had encountered of Lophophora koehresii) to be L. williamsii. His view that only two species exist (L. diffusa and L. williamsii) is the basis for Aragane & Sasaki’s name assignment.

Although the presence or absence of mescaline can easily be checked by chromatography, it is difficult to identify the species because not all L. williamsii contain mescaline. Chemotaxonomic identification of L. williamsii seems insufficient. DNA sequences of chloroplast trnL intron region in Lophophora plants were revealed to be beneficial for identification and showed a good correlation with mescaline content.” Sasaki et al. 2009.  

These samples were identified as L. williamsii in this study but were identified as L. williamsii var. decipiens in the literature.” [citing two illustrated cactus books by Y. Ito and by H. Hirao) Sasaki et al. 2009

Interestingly, although Lo-14, Lo-15, and Lo-16 were identified as L. williamsii in this study, these three samples were also identified as L. williamsii var. decipiens in previous literature. 16,18
Sequence alignments in the trnL intron region of those three samples were different from those of Lo-2 to Lo-11. Moreover, another study of ours revealed that Lo-14, Lo-15, and Lo-16 contained no mescaline (Table 1). Using this method, we can distinguish mescaline-containing Lophophora plants from mescaline-free ones if the reaction is stopped at 65 min.”
Sasaki et al. 2009 (Lo-14, Lo-15, and Lo-16 were their Lophophora fricii specimens. Lo-2 through Lo-11 were all L. williamsii.)

morphology of Lo-14 to 16 was similar to that of L. diffusa (Lo-17 to 20).” Aragane et al. 2011

It was reported that L. williamsii contained mescaline, but that L. diffusa did not [15, 16]; however, it was unknown whether that L. williamsii was within the wide classification that included L. fricii. In this study, we clarified for the first time that there are two groups of L. williamsii, one with mescaline (group 1) and the other without it (group 2), and that L. diffusa contained no mescaline.” Aragane et al. 2011

It is fascinating that they did not grasp that they had just produced might could be considered to be adequate proof that L. fricii merited recognition as a species separate from L. williamsii rather than being considered to be a nonmescaline form of L. williamsii.

Aragane et al. 2011 reported mescaline concentrations in their Japanese horticultural specimens to range from 1.27-4.83%. (The concentrations reported for those 13 averages to 3.2%.) This is a range AND an average value that is quite comparable to what has been reported from wild plants. 

Their presented sources produced some questions. In Sasaki et al. 2009 their plants were said to have been obtained from the “Medicinal Plant Garden, Tokyo Metropolitan Institute of Public Health“. In Aragane et al. 2011, most were listed as having been acquired through the “Internet” with all of the remainder coming from “Market (Mie Pref.)“.
Whether Aragane’s comments on dates and sources referred to the origin for the plants that Sasaki listed as being from the “Medicinal Plant Garden, Tokyo Metropolitan Institute of Public Health” or if Aragane’s comments were intended as a correction to Sasaki is not made clear.

These are the results from Aragane et al. 2011 concerning their specimens that were actually Lophophora williamsii:

#MescalineNameDateSource
Lo-13.72%Ubatama4-2005Internet
Lo-24.83%Ubatama4-2005Internet
Lo-32.22%Ubatama1-2005Market (Mie Pref.)
Lo-44.27%Ubatama1-2005Market (Mie Pref.)
Lo-53.85%Ubatama1-2005Market (Mie Pref.)
Lo-62.62%Ubatama4-2005Internet
Lo-73.82%Ubatama4-2005Internet
Lo-82.46%Ubatama4-2005Internet
Lo-92.94%Ubatama4-2005Internet
Lo-103.07%Ubatama4-2005Internet
Lo-113.54%Ougataubatama4-2005Internet
Lo-122.5%Kofukiubatama3-2005Internet
Lo-131.27%Ougataubatama4-2005Internet

Alkaloid content of Peyote:

Of the total alkaloid content:
30% is present as mescaline; 17% as pellotine.
Schultes & Hofmann 1980: 221.

Total alkaloid reported:
8.41% in dried “buttons”; 
0.47% in fresh whole plants;
0.2% in fresh roots
0.93% in fresh tops. 
Bruhn & Holmstedt 1974.
See more farther below.

Lewin was the first to isolate an alkaloid from peyote but it turned out to be both inactive entheogenically and a mixture of several alkaloids.

Heffter isolated 3 alkaloids from Lophophora williamsii and published his results and pharmacology in 1898. He named the active compound mescaline; determining it to be the active alkaloid by personal bioassays. [Heffter 1898a] Heffter named the other two alkaloids Anhalonidine and Lophophorine.

In 1976, 50 alkaloids had been observed;
(29 as substituted phenethylamines and 23 as tetrahydroisoquinolines): 
Shulgin 1976 cited Kapadia & Fayez 1973

A total of 35 isoquinolines had been reported prior to 1986, according to Menachery et al. 1986.
The number of compounds now mentioned in the chemical literature as actually being detected in the plant is 72. Of which some are questionable inclusions, some are clearly errors and a number alkaloids still need a second-party confirmation by someone. At the moment the presence of 63 alkaloids has been established.
No doubt new trace alkaloids in peyote will continue to be found in the future so long as people devise more sophisticated techniques and/or continue to look for them.
It should be pointed out that any and all recent finds of alkaloids have been in trace quantities. Most have been identified using elaborate ‘trapping’ techniques for identifying short-lived biosynthetic precursors. Which also means it is a bit of a stretch to consider those components in the alkaloid fraction since normal extraction processes will not be able to recover them.
Any alkaloids discovered in the future will similarly be of purely biochemical interest rather than pharmacological contributors to the action of peyote.

In an incredible move suggested more than a small level of ignorance (and, at best, a serious lack of factual information), in 1997 Congress made law a provision declaring every alkaloid contained in peyote to be a Schedule One controlled substance.
Since several of these are normal components of human body fluids (including blood, CSF and urine) and many are present in a wide variety of plants, what this actually means remains to be seen.
It is more than a bit disconcerting that there are now AT LEAST a handful of normally present endogenous substances that are presently considered Schedule 1 (potentially as many as 9 different compounds); placing every human on the planet in measurable and perennial violation of US federal law.

According to Anderson 1980, Todd found little variation in the alkaloid concentration between roots and tops of plants except for hordenine which he found to be present only in the roots. This is misleading as stated.
Todd 1969 analyzed two populations of Lophophora williamsii (and also L. diffusa from Querétaro) collected during June, [a time considered to be poor for mescaline and good for isoquinoline effects.] His collections were made by Anderson near Monclova, Coahuila and El Huizache, San Luis Potosí.
Todd found lophophorine to be present at higher concentrations than mescaline in the plants collected from both locations. [It has been noted by other workers that N-Methylated compounds, such as Lophophorine, are higher during summer than winter. See below.]
Anhalamine and anhalonidine were present at nearly the same concentration as mescaline in plants collected in Coahuila and at the same concentration as mescaline in plants collected from San Luis Potosí.
Anhalonine and anhalinine were present at about half the concentration of mescaline in both populations.
While pellotine in the tops was present at lower concentrations than mescaline in the Coahuilan population, it was present at roughly equal concentrations to mescaline in the San Luis Potosí population.
Mescaline concentrations were found to be substantially higher in the population collected from Coahuila.
The difference in mescaline concentration between the roots and tops was found to be far greater in plants from San Luis Potosí than Coahuila. The mescaline concentration in the roots of Coahuilan plants was equal to the concentration of mescaline in the tops of the San Luis Potosí originating plants. Only traces of mescaline were observed in the roots of the San Luis Potosí originating plants (the Texas ‘Peyote Gardens’ population is believed to be similar).
Pellotine was found to be equally distributed between roots and tops in both populations but was present in higher amounts in the San Luis Potosí population.
Anhalamine, anhalonidine, and anhalonine were found to be equally distributed between roots and tops and were present in similar concentration in both populations.
Anhalinine and lophophorine were found to be equally distributed between tops and roots in the population at San Luis Potosí and less concentrated in the roots of those from Coahuila. Concentration in the tops of both populations were the same.
I suspect that it was the collection during June that caused the marked differences between his results and those of other investigators. A similar examination should be made using collections taken at two month intervals during December through mid-May, the usual time of indigenous people’s collection for use. The isoquinoline content proportional to mescaline, as reported by Todd, is far higher than is normally mentioned in the literature. [All of Todd’s concentrations were estimated by co-tlc with known amounts.]
The Coahuilan population is considered to be a stronger variety or even a separate species by some. Chemically there may be justification for this [Note 21] and it should be targeted for propagation. Plants originating from the Texas “peyote gardens” are believed to be similar to the San Luis Potosí population.
Todd’s descriptions do not allow comparison with the published descriptive differences between var. williamsii and var. echinata.
Lundström 1971b reported that the N-methylated alkaloids (such as Lophophorine) were highest during summer in greenhouse maintained plants. N-Demethylated compounds were found to be higher in fall and winter than N-methylated derivatives.
This corresponds well to Peyote using peoples traditionally gathering plants from November through April or mid-May (actual period of harvest varying from group to group but largly falling within this time frame with thre being at least one group of Huichols harvesting in October) and also with subjective observations that December through early March are the times for the best psychological effects and the least somatic distress. I believe that January and February are the most ideal months of the year.

Siniscalco 1983 reported that keeping cultivated peyote plants under arid conditions for 6 months substantially increased their mescaline content. Their corresponding reported values differed as 0.1% compared to 2.74% by dry wt. That is a 27.4X difference which is highly significant as taking a plant from fresh to total dryness only increases the concentration ~10X.

In whole fresh plants of L. williamsii, a total alkaloid content of 0.47% was found. (Of this 60% was present as phenolic alkaloids and 40% as nonphenolic alkaloids.)
The fresh roots had a total alkaloid content of 0.20% (67% phenolic/ 33% nonphenolic). The fresh tops had a total alkaloid content of 0.93% (58% phenolic / 42% nonphenolic)
Plants were harvested in ?? (they mentioned that L. diffusa was harvested in June).
[They added that Lundström 1971b found 0.4% total alkaloids in whole plants of which 57.5% was phenolic and 42.5% was nonphenolic alkaloids.]

 

Analysis of old materials

Dried peyote buttons, freshly prepared, had a total alkaloid content of 8.41% (64% phenolic versus 36% nonphenolic).
87 year old peyote buttons (sent to Watson by Rusby in 1887) had an alkaloid content of 8.86% (65% phenolic and 35% nonphenolic).
The mescaline content of the 87 year old buttons was much less than the new ones but they did not have enough variables to account for the difference. Only minor differences were observed with regards to most of the other alkaloids. Anhalinine was also markedly lower in the old material. Hordenine and 3-Hydroxy-4,5-dimethoxyphenethylamine were almost completely lacking from the old material. The latter of these had been noted earlier by both Späth 1922 and Agurell & Lundström 1968 as being rather unstable.
Bruhn & Holmstedt 1974

Percentages of alkaloids reported in peyote:

Ott 1993 gave a nice summary; citing Bruhn & Holmstedt 1974 and Lundström 1971b:
8% Total alkaloids in dried peyote buttons, of which:
30% is mescaline (= 2.4-2.7%) (~400 mg. per 16 grams of dried cactus)
17% is pellotine (peyotline) (= 1.4-1.5%)
14% anhalonidine (= 1.2-1.3%)
8% anhalamine (= 0.6-0.7%)
8% hordenine (= 0.6-0.7%)
5% lophophorine (= 0.4%)

Alkaloid percentages according to Kapadia & Fayez 1973.
References cited are theirs. (All percentages of total alkaloid content are from Lundström 1971)

Mescaline 6% (30% of total alkaloid content.)
 Anonymous 1959

Pellotine (peyotline) 0.74% (17% of total alkaloid content.) 
Heffter 1894b [This may have been from L. diffusa.]

Anhalonidine 5% (14% of total alkaloid content.)
Heffter 1896a

Anhalamine 0.1% (8% of total alkaloid content.)
Heffter 1901
(Späth & Becke 1935b also reported 0.1%.)

Lophophorine 0.5% (5% of total alkaloid content.)
Heffter 1896a

Anhalonine 3% (3% of total alkaloid content.)
Heffter 1896a

Anhalinine 0.01% (0.5% of total alkaloid content.)
Späth & Becke 1935a & 1935b

Anhalidine 0.001% (2% of total alkaloid content.)
Späth & Becke 1935a & 1935b

Hordenine 0.004% (8% of total alkaloid content.)

N-Methyl-4-hydroxy-3-methoxyphenethylamine (<0.5% of total
alkaloid content.)

N,N-Dimethyl-4-hydroxy-3-methoxyphenethylamine (0.5-2% of total alkaloid content.)

3-Demethylmescaline (1-5% of total alkaloid content was found in fresh material by Lundström & Agurell 1971)

N,N-Dimethyl-3-demethylmescaline (0.5% of total alkaloid content.)

N-Methylmescaline 0.002% (3% of total alkaloid content.)

O-Methylanhalonidine (<0.5% of total alkaloid content.)

Isopellotine (0.5% of total alkaloid content.)

Peyophorine (0.5% of total alkaloid content.)

Isoanhalidine (trace)

Isoanhalonidine (trace)

Isoanhalamine (trace)

Tyramine (trace)

N-Methyltyramine (trace)

Epinine (trace)

3,4-Dimethoxyphenethylamine (trace)

3,4-Dihydroxy-5-methoxy-phenethylamine (trace)

N-methyl-3-demethylmescaline (trace)

[All others found by other workers were also trace components.]
For more information on isolations and dates see elsewhere here.

 

Lundström 1971b found a total alkaloid content of 0.4% w/w to be present in the fresh buttons and noted that 0.41% had been determined by Rouhier (as cited by Anonymous 1959). 

First pharmacological study of peyote was published in Lewin 1888a & 1894a.

An Abbreviated Chronology of the Identification of the Peyote alkaloids

The first report of alkaloids in peyote was the laboratory report of F.A. Thompson at Parke-Davis but Lewin was the first to publish. (Bruhn & Holmstedt 1974)

1888
Anhalonine (crystalline but not a pure compound)
Lewin (1888) Naunyn-Schmiedebergs Archiv fur Experimentelle Pathologie und Pharmakologie, 24: 401-411

1894 
Pellotine This probably was from L. diffusa  rather than L. williamsii. [The source of Heffter’s material is not known as this apparently came from German collectors with no identification of locality. Considerable trade of peyote collected from the locality of L. diffusa existed in early times and it was not differentiated from L. williamsii so it is probable that pellotine was not actually isolated from L. williamsii by Heffter. He referred to the material in this analysis as Anhalonium williamsii rather than A. lewinii, the latter being his source of mescaline below. See Bruhn & Holmstedt 1974 or the A. lewinii discussion herein.]
Heffter (1894)b Berichte der Deutschen Chemischen Gesellschaft, 27: 2975-2979.

1896 
Anhalonidine
Lophophorine
Mescaline
Heffter (1896)a Berichte der Deutschen Chemischen Gesellschaft, 29: 216-227.

1899

Anhalamine

    Kauder (1899) Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 237: 190-198.

1935 
Anhalinine
Späth & Beck (1935) Berichte der Deutschen Chemischen Gesellschaft, 68 (3): 501-505.
Anhalidine
Späth & Beck (1935) Berichte der Deutschen Chemischen Gesellschaft, 68 (5): 944-945.

1937 
N-Methylmescaline
Späth & Bruck (1937) Berichte der Deutschen Chemischen Gesellschaft, 70 (12): 2446-2450.

1938 
N-Acetylmescaline
Späth & Bruck (1938) Berichte der Deutschen Chemischen Gesellschaft, 71 (6): 1275-1276.

1939 
O-Methylanhalonidine
Späth and Bruck (1939) Berichte der Deutschen Chemischen Gesellschaft, 72 (2): 334-338.

1965 
Hordenine
McLaughlin & Paul (1965) Journal of Pharmaceutical Sciences, 54 (4): 661.<
(Confirmed in McLaughlin & Paul 1966 Lloydia, 29 (4): 315-327.)
See Todd 1969 Lloydia, 32 (3): 395-398.

1966 
Tyramine
N-Methyltyramine
Candicine (Identified by tlc. Presence in peyote is in question, see Kapadia et al. 1968 Journal of Pharmaceutical Sciences, 57 (2): 254-262.)
McLaughlin & Paul (1966) Lloydia, 29 (4): 315-327. (In addition to hordenine)

1967 
Peyonine
Kapadia & Shah (1967) Lloydia, 30: 287. (Proceedings.)
See also Kapadia & Highet (1968) Journal of Pharmaceutical Sciences, 57: 191-192

1968 
3-Hydroxy-4,5-dimethoxyphenethylamine
Agurell & Lundström 1968 The Chemical Society, London. Chemical Communications, 1638-1639.
(Confirmed by Kapadia et al. (1969)a Journal of Pharmaceutical Sciences, 58 (9): 1157-159.)
N-Acetylanhalamine
N-Acetylanhalonine
N-Acetyl-3-hydroxy-4,5-dimethoxyphenethylamine 
N-Formylanhalamine
N-Formylanhalinine
N-Formylanhalonidine
N-Formylanhalonine
N-Formyl-3-hydroxy-4,5-dimethoxyphenethylamine 
N-Formylmescaline
N-Formyl-O-methylanhalonidine 
Mescaline maleimide
Mescaline malimide
Mescaline succinamide
Mescalotam
Peyoglutam 
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
Peyophorine 
Kapadia & Fales (1968)b Journal of Pharmaceutical Sciences, 57 (11): 2017-2018, and Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications,24: 1688-1689.
Anhalotine (as iodide)
Choline
Lophotine (as iodide) 
Peyotine (as iodide) 
Kapadia et al. (1968) Journal of Pharmaceutical Sciences, 57 (2): 254-262.
3,4-Dimethoxyphenethylamine 
Lundström & Agurell (1968) Journal of Chromatography, 36 (1): 105-108.

1969 
Peyoxylic acid
Peyoruvic acid 
Kapadia et al. (1969) Paper presented at the 116th Meeting of the American Pharmaceutical Association, Montreal, Canada. May 18-22, and Kapadia et al. (1970)b Journal of the American Chemical Society, 92 (23): 6943-6951.

1970 
Mescaline citrimide 
Mescaline isocitrimide lactone
Kapadia & Fales (1970)a Lloydia, 33 (4): 492. (Proceedings.) (Paper presented at the “11th Annual Meeting of the American Society of Pharmacognosy (Vienna, Austria) July 1970)
Peyoglunal
Kapadia et al. (1970)a Lloydia, 33 (4): 492. (Proceedings.)

1971 
Mescaloxylic acid
Mescaloruvic acid
Kapadia et al. (1971) Paper presented at the 118th Meeting of the American Pharmaceutical Association, San Francisco, California, March 27-April 2. “Some newer synthetic cactus alkaloid analogs.” and Kapadia and Hussain (1972) Journal of Pharmaceutical Sciences, 61 (7): 1172-1173.
Dopamine (3,4-Dihydroxyphenethylamine)
Epinine (N-Methyl-3,4-dihydroxyphenethylamine)
4-Hydroxy-3-methoxyphenethylamine 
N-Methyl-4-hydroxy-3-methoxyphenethylamine 
N,N-Dimethyl-4-hydroxy-3-methoxyphenethylamine 
N-Methyl-3,4-dimethoxyphenethylamine
3,4-Dihydroxy-5-methoxyphenethylamine
Lundström (1971) Acta Chemica Scandinavica, 25 (9): 3489-3499.
N,N-Dimethyl-3-hydroxy-4,5-dimethoxyphenethylamine 
N-Methyl-3-hydroxy-4,5-dimethoxyphenethylamine 
Lundström (1971) Acta Pharmceutica Suecica, 8: 485-496.

1972

6,7-Dimethoxy-8-hydroxy-3,4-dihydroisoquinolinium inner salt

1,2-Dimethyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinolinium inner salt
1-Methyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinoline
2-Methyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinolinium inner salt
Fujita et al. (1972) Yakugaku Zasshi, 92 (4): 482-489 (this inclusion may not belong here as this might not have been L. williamsii.)
Isoanhalamine
Isoanhalidine 
Isoanhalonidine
Isopellotine 
Lundström (1972) Acta Chemica Scandinavica, 26 (3): 1295-1297.

1973 
O-Methylpeyoxylic acid 
O-Methylpeyoruvic acid 
Kapadia et al. (1973) Journal of Heterocyclic Chemistry, 10 (1): 135-136.

1977 
Pellotine determined to exist in optically active form in the cactus. (This had been an unresolved question for many years due to rapid and ready racemization)
Cymerman Craig et al. (1977) Journal of the American Chemical Society, 99 (24): 7996-8002.

1996 
Serotonin was claimed; using ion-interaction HPLC. Its identity was never actually proven and it was not isolated. It presently lacks confirmation.
Gennaro et al. (1996) Analytical Letters, 29 (13): 2399-2409.

2008 
3,4-Methylenedioxyphenethylamine (Homopiperonylamine)
3-Methoxy-4,5-methylenedioxyphenethylamine (Lophophine) 
N,N-Dimethyl-3,4-methylenedioxyphenethylamine (Lobivine) 
These three compounds were reported but this needs to be taken with caution as their actual isolation and characterization was never performed. All identifications relied entirely on the spectral data of the extracted alkaloids and their corresponding derivated forms. The actual presence of these alkaloids still needs to be independently confirmed. A number of comments from this paper also need questioning, especially concerning their peculiar speculative assertions of their contributions to activity and their baseless allusions to MDMA or designer drug activity. (It was incredibly entitled “Ecstacy analogues found in cacti.” as if the activity of MDMA analogs did not require alpha substitution.) In a personal conversation, shortly after the appearance of this paper, Shulgin described the inclusion of his name as an author to be an “embarassment“. 
Bruhn et al. (008) Journal of Psychoactive Drugs, 40 (2): 219-222. 
Shulgin had however voiced his anticipation, in PIHKAL, that someday someone WOULD find 3-Methoxy-4,5-methylenedioxy-phenethylamine in a cactus and that it was a surprise that it had not been reported already.

Mrs. Anna B. Nickels, a long-time collector of cacti, is generally given credit for bringing peyote to the attention of Parke-Davis. [Safford 1908 is the first source I can find which claims this.]
Slotkin 1955 dismissed this on three counts: 
1) Parke, Davis and Co. was unable to find any records concerning Mrs. Nickels,
2) Peyote from Parke, Davis and Co. was used by Lewin, and was said by both sources to have originated in Mexico; Mrs. Nickels lived in Laredo.
3) Mrs Nickels referred to peyote as mescal buttons.
Slotkin presented some circumstantial evidence that J.R. Briggs may have been the one who brought peyote to the attention of pharmaceutical science:
1) Briggs’ brother lived in Mexico and supplied him with peyote. 
2) Park, Davis’ files on peyote begin with a clipping of a Briggs article. 
3) Both Lewin and Briggs used the unusual name of muscale buttons.

Mrs. Nickels did bring the fact of this plant having medicinal use among native people to the attention of John M. Coulter (around 1892-3). She referred to them as “mescal buttons”.
It might be added that Mrs. Nickels had a large cactus exhibit in Chicago’s 1893 Colombian Exposition and was noted by Liberty Hyde Bailey as having published the first catalog of cacti published in the US (as the price list issued for her cactus retail business ~1876)
A couple of points arise concerning the claims of Slotkin; neither of which am I able to resolve:
Omer C. Stewart was furnished (By G.A. Bender) with a copy of a letter that Mrs. Nickels had sent to Parke-Davis and Company in Detroit dated 11 July 1888. 
In this letter, she referred to Anhalonium Williamsii as Piotes.

Stewart also presents her as the cactus supplier who provided J.R. Briggs, and hence Parke-Davis, with peyote when Brigg’s first supplier failed to provide what they needed.
Bender 1969 presents a somewhat different view of the same account and presents Parke-Davis as becoming aware of mescal buttons due to reading J.R. Briggs’ published account of his ingestion. In Bender’s account, Briggs was contacted by Parke-Davis and requested to procure some mescal buttons on their behalf, which he eventually accomplished. Interestingly, Parke-Davis apparently lacked any understanding of the nature of their source plant so they sought outside help at identification. One of the dried buttons they had mailed to Lewin in Germany is what ended up in Hennings’ hands and became Anhalonium lewinii.  

Effects of peyote summarized

See more details under Mescaline pharmacology (in the book PDF Part C The Cactus Alkaloids) or briefly in the following section.
Perhaps the best summation of peyote’s overall effects to-date was made in 1940 by Richard Evans Schultes:
Because of the physiological activity of these constituents of the cactus, peyote is capable of inducing an intoxication which is characterized by a feeling of ease and well-being, by control of the limbs and senses, by absence of violence, and occasionally by visual and auditory hallucinations and abnormal synaesthesiae. There are seldom uncomfortable after-effects among users. As a result of this remarkable type of intoxication, peyote has come to be regarded by many Indians as the vegetal incarnation of a deity.” (page 177)
The sustaining and stimulating properties of Lophophora Williamsii which enable the user to do an excessive amount of work without feeling fatigue are hardly separable from those properties which may be called curative.” (page 178)

Prentis_Morgan_Anhalonium_HCl_fig3_2wide
Anhalinine HCl crystals from Prentis & Morgan

 

Pharmacological overview of the non-mescaline alkaloid content of peyote

    No hallucinogenic activity has yet been demonstrated for any peyote alkaloid other than mescaline. [There is one mention of hallucinations experienced with a very large dosage of pellotine and at least one claim of a hallucinogenic experience resulting from the ingestion of L. diffusa but they stand in contrast to all other observations.]
Pharmacology of mescaline and more details concerning the rest of the alkaloids can be found in the book PDF Part C The Cactus Alkaloids. Only a relative few of the peyote alkaloids are mentioned in this section. 
Those listed have some nature of activity or lack of activity reported in the literature. Other alkaloids present in peyote, such as anhalinine are unlikely to contribute substantially, if at all, to its effects. This is due to their inactivity pharmacologically and/or, most often, to their extremely low concentrations.

Anhalamine

Found to be hardly active as anticonvulsant, tranquilizer or muscle relaxant by Brossi et al. 1966

Anhalidine

Found to be hardly active as anticonvulsant, tranquilizer or muscle relaxant by Brossi et al. 1966

Anhalonidine

Probably does not contribute to the pharmacology as it is one fourth as active as pellotine. Shulgin 1973
Heffter found doses of 20-25 mg of the hydrochloride produced narcosis in frogs followed by increased excitability. Complete paralysis was produced by larger dosages. A curarizing effect was caused by dosages of 30 to 50 mg. No significant effects were seen in mammals. Heffter 1898a
Said to produce slight sleepiness and a dull sensation in the head. LaBarre 1975 citing Rouhier’s Monographie pp. 227-232.
Found to be hardly active as anticonvulsant, tranquilizer or muscle relaxant by Brossi et al. 1966.

Anhalonine

Heffter 1898a found 5-10 mg injected into frogs produced an increase in the reflex excitability after a phase of paresis. Similar action was noted in rabbits but hyperexcitability was predominate. (Heffter also described other effects.)

Hordenine

Active as a stimulant [Bruhn & Bruhn 1973] but a 100 mg. dose was found by Heffter to be inactive. [Ott 1993] Hordenine may potentially contribute some activity as a norepinephrine reuptake inhibitor: Barwell et al. 1989. However, the extent of its actual contribution remains to be studied.
As Todd found this present only in the roots it may be doubtful that it contributes to the pharmacology of peyote although the claim from some users that they get mroe when eating the roots might merit evaluation. It is presently unknown whether the reported presence of hordenine in peyote buttons by other researchers reflects its occurrence in the tops during normal times of traditional harvest (perhaps before use as a biosynthetic precursor) versus Todd’s analysis occurring during June or whether it is due to the presence of roots or partial roots on the plants these other workers analyzed. (Some other workers did analyze WHOLE plants during their work.
See McLaughlin & Paul 1965, 1966 & 1967 and Rao 1970.
McLaughlin & Paul 1965 purchased their material from Penick.
McLaughlin & Paul 1965 was cited by McLaughlin & Paul 1966 for their procedure in processing the plants. In their 1966 work on biosynthesis they used plants obtained from Mexico which were maintained in a greenhouse.]

Found to cause paralysis of the CNS in frogs without previous excitation by Heffter 1894a.
Small doses have no effect on blood circulation but larger ones cause hypertension and accelerated pulse. Very large doses cause death by respiratory arrest.
Pressure effect is not of central origin but is due to stimulation of cardiac muscle. [Rietschel 1937a & 1937b]
Less active than adrenaline, more similar to ephedrine than adrenaline.
Other researchers reported a nicotine like action [Raymond-Hamet 1933a, 1933b & 1939 and Ludueña, as cited in Reti 1959]
Large doses decrease or reverse the hypertensive action of adrenaline. [Raymond-Hamet 1936]

Reported highly antiseptic and to have inhibiting effect on some soluble ferments. [Camus 1906a-d]
Comments partially adapted from Kapadia & Fayez 1970

The antibacterial and wound healing reputation of peyote and other cacti has been attributed to the presence of hordenine. See:
McCleary 1960 who studied the effects of a water soluble crystalline material extracted from peyote, which they named peyocactin, in vitro on 18 penicillin resistant strains including Staphylococcus aureus and Staphylococcus pyogenes. It inhibited all strains.

McCleary & Walkington 1964 found inhibitory effects in vivo on
mice inoculated with toxic strains of S. aureus. Found that other cacti were effective on some strains but none were as widely effective as peyote.

Rao 1970 showed that peyocactin and hordenine were identical.
Hordenine has well known antibacterial properties and was generally assumed to be the reason for the bacterial inhibition observed by McCleary above. It should be noted that in spite of peyote’s greater activity in this regard, other cacti they evaluated have been found to have higher hordenine contents. While most people have assumed that the activity is due solely to hordenine, this suggests that the matter is not yet cut and dried and some study might be worthwhile.
McLaughlin & Paul 1966 also found in vitro antibiotic activity against a broad range of microorganisms but were unable to document any significant in vivo activity.

Effects of Lophophorine on blood pressure in a cat (Dixon 1899)
Effects of Lophophorine on blood pressure in a cat (Dixon 1899)

Lophophorine

“…is highly toxic and produces strychnine-like convulsions at 12 mg./kg. doses but it produces nausea in human being at much lower doses.“ [Ott 1993 citing Anderson 1980] 
Heffter 1898a “found a 20 mg. dose of lophophorine to produce vasodilation and headache.” [Ott 1993]
Shulgin 1973 & 1976 noted that all toxicity data and the assertions of its “highly toxic” nature is based on animal studies and human evaluations limited to Heffter’s single published report.
Administration of the alkaloid was said to produce an accentuated sickening feeling in the back of the head after 15 minutes, accompanied by hotness, blushing of the face and a slight slowing of the pulse. The effects are said to disappear after 40 minutes. [LaBarre 1975 citing Rouhier’s Monographie 227-232 who was referring to Heffter.]
Heffter found that 0.25-1 mg of injected hydrochloride produced a lengthy tetany in the frog. The increased excitability may last for several days but the animal recovers. (He noted no apparent action on the isolated frog heart.)
In rabbits hyperexcitability and accelerated respiration were noted at 7 mg/kg. Tetany was induced at 12.5 mg/kg and death at 15-20 mg/kg.
Intravenous injection of 2.5 mg increases blood pressure but higher doses are hypotensive, lacking a specific action on the heart. [Heffter 1898a]

Pellotine

Sedative effects at 50 mg. levels in adult humans. From Ott 1993
Temporary convulsion were caused in frogs, dogs and cats by dosages of 5-10 mg. [Ott 1993 citing Heffter 1898a]
Said to reduce the pulse by approximately a quarter in about an hour. Reported to cause heaviness of the eyelids, sensation of fatigue and an aversion to all physical and mental effort. [LaBarre 1975 citing Rouhier’s Monographie pp. 227-232]
Believed by some to be useful in man as a relatively safe narcotic. [Kapadia & Fayez 1970 referred to authors cited by Joachimoglu & Keeser 1924]
It was found to be hardly active in animals as anticonvulsant, tranquilizer or muscle relaxant by Brossi et al. 1966

Sasha Shulgin & out-of-this-world friends circa 2003
Sasha Shulgin & three out-of-this-world friends circa 2003

 

 

Alkaloids identified in peyote

More than 70 alkaloids have been published in the literature but some of those are clear errors, others have been questioned or lack confirmation. Only around 63 of those are actually confirmed. 
Candicine and O-methylpellotine are disputed, the first as other workers were unable to identify it and the second as it apparently is in L. diffusa but not L. williamsii.
One could also question 1,2-Dimethyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinolinium inner salt as it was was identified entirely by UV and comparison with similar structures.

The following list was organized after Anderson but has been updated and expanded to include a summation of the available reports for each alkaloid. 
For physical data: please see the book “The Cactus Alkaloids

Mono-oxygenated phenethylamines:

Tyramine

tlc
McLaughlin & Paul (1966) Lloydia, 29: 315.
(0.001% dry wt: McLaughlin & Paul 1966; trace: Lundström 1971a.
Also in Habermann 1978b (from Štarha nd)

N-Methyltyramine

tlc, mp, mmp, ir
McLaughlin & Paul (1966) Lloydia, 29 (4): 315-327.
(0.012% dry wt: McLaughlin & Paul 1966; trace: Lundström 1971a.

Hordenine

tlc, mp, mmp, ir
McLaughlin & Paul (1965) Journal of Pharmaceutical Sciences, 54 (4): 661.
 (Confirmed in McLaughlin & Paul (1966) Lloydia, 29 (4): 315-327.)
(0.6-0.7% dry wt: Lundström 1971b; (0.008% dry wt.) McLaughlin & Paul 1966; Todd 1969 found it only in roots (tlc).
[Also in Habermann 1978b (from Štarha nd)]
[8% of total alkaloid content: Lundström 1971b]

Candicine

(tlc) Presence in peyote is in question
McLaughlin & Paul (1966) Lloydia, 29: 315-327. (Suspected presence based on tlc.) 
Kapadia et al. 1968 could not confirm. Found other quaternary alkaloids but were unable to find candicine. Nor could Davis et al. 1983

Dioxygenated phenethylamines:

Dopamine

glc, gc-ms<
Lundström (1971)a Acta Chemica Scandinavica, 25 (9): 3489-3499 
(trace: Lundström 1971a)

Epinine

glc, gc-ms
Lundström (1971)a Acta Chemica Scandinavica, 25 (9): 3489-3499 
(trace: Lundström 1971a)

4-Hydroxy-3-methoxyphenethylamine

(3-Methoxytyramine)
glc, gc-ms
Lundström (1971)a Acta Chemica Scandinavica, 25 (9): 3489-3499 
(trace: Lundström 1971a)

N-Methyl-4-hydroxy-3-methoxyphenethylamine

glc, gc-ms
Lundström (1971)a Acta Chemica Scandinavica, 25 (9): 3489-3499 
(trace: Lundström 1971a; <0.5% of total alkaloid content: Lundström 1971b]

N,N-Dimethyl-4-hydroxy-3-methoxyphenethylamine

glc, gc-ms
Lundström (1971)a Acta Chemica Scandinavica, 25 (9): 3489-3499 
(trace: Lundström 1971a; 0.5-2% of total alkaloid content: Lundström
1971b)

3,4-Dimethoxyphenethylamine

glc, gc-ms
Lundström & Agurell (1968) Journal of Chromatography 36 (1): 105-108. 
(trace: Lundström & Agurell 1968 and Lundström 1971a. Also in Habermann 1978b: from Štarha nd)

N-Methyl-3,4-dimethoxyphenethylamine

glc, gc-ms
Lundström (1971)a Acta Chemica Scandinavica, 25 (9): 3489-3499 
(trace: Lundström 1971a)

3,4-Methylenedioxyphenethylamine

(Homopiperonylamine)
HPLC
Bruhn et al (2008)
(Reportedly observed but lacking isolation & characterization and independent confirmation.)

N,N-Dimethyl-3,4-methylenedioxyphenethylamine

(Lobivine)
HPLC
Bruhn et al (2008)
(Reportedly observed but lacking isolation, characterization and independent confirmation.)

Trioxygenated phenethylamines and related amides:

3,4-Dihydroxy-5-methoxyphenethylamine

glc, gc-ms
Lundström (1971)a Acta Chemica Scandinavica, 25 (9): 3489-3499 
(trace: Lundström 1971a)

3-Hydroxy-4,5-dimethoxyphenethylamine

(3-Demethylmescaline)
gc, gc-ms
Kapadia et al. (1969)a Journal of Pharmaceutical Sciences, 58 (9): 1157-1159.
Agurell & Lundström (1968) The Chemical Society, London. Chemical Communications, 24: 1638-1639. 
(5% of total alkaloid: Agurell & Lundström 1968; 1-5% of total alkaloid content in fresh material: Lundström & Agurell 1971b. Also (identified) by Kapadia et al. 1969a and Agurell & Lundström 1968)

N-Methyl-3-hydroxy-4,5-dimethoxyphenethylamine

gc, gc-ms
Lundström (1971)c Acta Pharmaceutica Suecica, 8 (5): 485-496
(trace: Lundström 1971c)

N,N-Dimethyl-3-hydroxy-4,5-dimethoxyphenethylamine

gc, gc-ms

Lundström (1971)c Acta Pharmaceutica Suecica, 8 (5): 485-496

(0.04% dry weight i.e. 0.5% of 8% total alkaloid content: Lundström 1971c; 0.5% of total alkaloid content: Lundström 1971b)

N-Formyl-3-hydroxy-4,5-dimethoxyphenethylamine

(N-Formyl-3-demethylmescaline)
gc, gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
(trace: Kapadia & Fales 1968a)

N-Acetyl-3-hydroxy-4,5-dimethoxyphenethylamine

    (N-Acetyl-3-demethylmescaline)

gc-ms

Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.

(trace: Kapadia & Fales 1968a)

3-Methoxy-4,5-methylenedioxyphenethylamine

(Lophophine)
HPLC
Bruhn et al (2008)Lacking isolation & characterization. In need of confirmation.

Mescaline (3,4,5-Trimethoxyphenethylamine)

mp, mmp
Heffter (1896)a Berichte der Deutschen Chemischen Gesellschaft, 29: 216-227 (original isolation) but the structure was not actually determined until Späth (1919) Monatshefte fuer Chemie, 40: 129-154.
([0.10-]0.9-6.0[-6.3]% dry wt. has been reported [Note 22] [Anonymous 1959, Heffter 1896a, Lundström 1971b, Martin & Alexander 1968 & Siniscalco 1983); 
Anderson 1980 cited Kelsey 1959 (0.9%), Bergman 1971 (1.5%), Fischer 1958 (3%), Heffter 1896a (4.6-5.6%[-6.3%])]; 
2.4-2.7 % dry (~400 mg. per 16 grams of dried cactus) Ott 1993 citing Bruhn & Holmstedt 1974 and Lundström 1971b 
[Crosby & McLaughlin 1973 stated peyote can reach 6% but rarely exceeds 1% (dry wt.)] 
[Tops>>Roots; Todd 1969 [Note 23]] 
Siniscalco 1983 reported the isolation of 0.10% (well irrigated),
0.93% (grafted) and up to 2.74% dry weight (after 6 months of dry conditions) from plants cultivated in Italy; 0.1 to 0.2% by fresh weight is common

Friends with extraction experience found fresh Texas plants to average 0.2% during 1970s

75-125 mg of HCl was recovered from 70-140 gm plants greenhouse grown in northern Europe. Lundström & Agurell 1971b (This approaches 0.1% by fresh weight) [Also in Habermann 1978a & 1978b (from Štarha nd)] [30% of total alkaloid content: Lundström 1971b]

[As L. williamsii var. typica Croizat: 0.709% (± 0.032) dry wt.
Habermann 1978a (from Štarha 1997)]

N-Methylmescaline

mp, mmp
Späth & Bruck (1937) Berichte der Deutschen Chemischen Gesellschaft, 70 (12): 2446-2450. 
(0.24% dry wt., 3% of total alkaloid: Lundström 1971b)

 N-Formylmescaline

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.

(trace: Kapadia & Fales 1968a)

N-Acetylmescaline

mp, mmp
Späth & Bruck (1938) Berichte der Deutschen Chemischen Gesellschaft, 71 (6): 1275-1276. 
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689. 
(trace: Späth & Bruck 1938 and Kapadia & Fales 1968a)

Tetrahydroisoquinolines and related amides:

Anhalamine

mp, mmp

Kauder (1899) Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 237: 190-198.
(0.1-0.7% dry wt. has been reported: Späth & Becke 1935b and Lundström 1971b; Also in Habermann 1974a (from Štarha nd); 8% of total alkaloid content: Lundström 1971b)

N-Formylanhalamine

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.

(trace: Kapadia & Fales 1968a)

N-Acetylanhalamine

gc-ms

Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.

(trace: Kapadia & Fales 1968a)

Isoanhalamine

gc, gc-ms
Lundström (1972) Acta Chemica Scandinavica, 26: 1295-1297. 
(trace: Lundström 1972)

Anhalidine

mp, mmp
Späth & Beck (1935)b Berichte der Deutschen Chemischen Gesellschaft, 68 (5): 944-945.
(0.001% dry wt: Späth & Becke 1935b; 0.16% dry wt. i.e. 2% of 8% total alkaloid content: Lundström 1971b)

Anhalotine (4° amine isolated as Iodide)

ir, nmr, uv
Kapadia et al. (1968) Journal of Pharmaceutical Sciences, 57 (2): 254-262.
(0.0003% dry wt: Kapadia et al. 1968)

Isoanhalidine

gc, gc-ms
Lundström (1972) Acta Chemica Scandinavica, 26: 1295-1297. 
(trace: Lundström 1972 & 1971b)

Anhalinine

mp, mmp
Späth & Beck (1935) Berichte der Deutschen Chemischen Gesellschaft, 68 (3): 501-505.
(0.01% dry wt: Späth & Becke 1935b; 0.04% dry wt., 0.5% of total alkaloid content: Lundström 1971b)

N-Formylanhalinine

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689. 
(trace: Kapadia & Fales 1968)

Anhalonidine

mp, mmp
Heffter (1896)a Berichte der Deutschen Chemischen Gesellschaft, 29: 216-227. 
(1.12% dry wt., 14% of total alkaloid content: Lundström 1971b; Also
in Habermann 1974a: from Štarha nd)

Pellotine

mp, mmp
Heffter (1894)b Berichte der Deutschen Chemischen Gesellschaft, 27: 2975-2979. 
Kauder, E. (1899) Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 237: 190-198.
(±)-Pellotine
UV, IR, NMR
Kapadia et al. (1968) Journal of Pharmaceutical Sciences, 57 (2): 254-262.
(-) Pellotine
UV, CD
Cymerman Craig, J. et al. (1977) Journal of the American Chemical Society 99 (24): 7996-8002. 
1.36% dry weight: Lundström 1971b;
Also (%?) Habermann 1974a, 1978a & 1978b: from Štarha nd;
17% of total alkaloid content: Lundström 1971;
As L. williamsii var. typica: 0.296% (± 0.065) Habermann 1978a: from Štarha in Grym 1997.

Peyotine  (4° amine isolated as Iodide)

Pellotine methiodide
mp, UV, IR
Kapadia et al. (1968) Journal of Pharmaceutical Sciences, 57 (2): 254-262.
(0.00015% dry wt: Kapadia et al. 1968)

N-Formylanhalonidine

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
(trace: Kapadia & Fales 1968a)

Isoanhalonidine

gc, gc-ms
Lundström (1972) Acta Chemica Scandinavica, 26: 1295-1297.
(trace: Lundström 1972)

Isopellotine

gc, gc-ms
Lundström (1972) Acta Chemica Scandinavica, 26: 1295-1297. 
(0.04% dry weight, 0.5% of total alkaloid content: Lundström 1971b)

S-(+)-O-Methylanhalonidine

O-Methyl-d-anhalonidine
mp, mmp
Späth & Bruck (1939) Berichte der Deutschen Chemischen Gesellschaft, 72 (2): 334-338.
(0.04% dry wt., <0.5% of total alkaloid content: Lundström 1971b)

N-Formyl-O-methylanhalonidine

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689. 
(trace: Kapadia & Fales 1968a)

O-Methylpellotine

gc, gc-ms (using L. diffusa)
[Bruhn & Agurell (1975) Phytochemistry,14: 1442-1443.]
Presence in L. williamsii is in doubt. It is included by Mata & McLaughlin 1982 but they do not list individual references for the compounds. 
Bruhn & Agurell believed that it is unique to L. diffusa but it was later it was found in Pachycereus weberi.
I am still reviewing Mata & McLaughlin’s references in case someone found this as a trace component in peyote but that does not presently appear to be likely. Štarha did not detect it in L. fricii or L. jourdaniana but DID report it in L. koehresii. Obviously Štarha’s work was not available to Mata & McLaughlin in 1982

6,7-Dimethoxy-8-hydroxy-3,4-dihydroisoquinoline

mp, UV, IR, NMR, MS
Fujita et al. (1972) Yakugaku Zasshi, 92 (4): 482-489.
(Journal of the Pharmaceutical Society of Japan)
(0.0008% fresh weight: Fujita et al. 1972; as L. williamsii var. caespitosa – note: this might not have been L. williamsii.)

2-Methyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinolinium inner salt

mp, uv, IR, NMR, MS
Fujita et al. (1972) , 92 (4): 482-489.
(Journal of the Pharmaceutical Society of Japan)
(0.001% fresh weight: Fujita et al. 1972: as L. williamsii var. caespitosa – note: this might not have been L. williamsii.)

1-Methyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinoline

mp, UV, NMR, ms
Fujita et al. (1972) , 92 (4): 482-489
(0.0001% fresh weight: Fujita et al. 1972: as L. williamsii var.
caespitosa – note: this might not have been L. williamsii.)

1,2-Dimethyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinolinium inner salt

 UV
Fujita et al. (1972) , 92 (4): 482-489.
(0.00008% fresh wt: Fujita et al. 1972: as L. williamsii var. caespitosa – note: this might not have been L. williamsii.)

Lophotine (4° amine isolated as Iodide)

ir, nmr, uv
Kapadia et al. (1968) Journal of Pharmaceutical Sciences, 57 (2): 254-262.
(0.0002% dry weight: Kapadia et al. 1968)

S-(-)-Anhalonine

mp, mmp
Heffter (1896)a Berichte der Deutschen Chemischen Gesellschaft, 29: 216-227.
UV, IR, NMR
Kapadia et al. (1968) Journal of Pharmaceutical Sciences, 57 (2): 254-262
(0.24% dry wt., 3% of total alkaloid content: Lundström 1971b)

S-(-)-Lophophorine

mp, mmp
Heffter (1896)a Berichte der Deutschen Chemischen Gesellschaft, 29: 216-227.
UV, IR, NMR
Kapadia et al. (1968) Journal of Pharmaceutical Sciences, 57 (2): 254-262.
(0.4% dry wt: Lundström 1971b;
0.5% dry wt: Heffter 1898c.
[Also in Habermann 1974a (from Štarha nd)]
5% of total alkaloid content: Lundström 1971b;
Appeared to be the major alkaloid in 2 sorts of summer collected plants: tlc by Todd 1969)

N-Formylanhalonine

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
(trace: Kapadia & Fales 1968a)

N-Acetylanhalonine

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
(trace: Kapadia & Fales 1968a)

Peyophorine

tlc, gc, ir, ms, mp
Kapadia & Fales (1968)b Journal of Pharmaceutical Sciences,. 57 (11): 2017-2018.
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
(trace: Kapadia & Fales 1968a; 0.04% dry wt., 0.5% of total alkaloid content: Lundström 1971b) 

Conjugates with Krebs Acids:

Peyoxylic acid

gc

Kapadia & Fayez (1973) cites Kapadia et al. (1969) 116th Meeting of the American Pharmaceutical Association, Montreal, Canada. May 18-22. “Identification and synthesis of 3-demethylmescaline, a plausible intermediate in the biosynthesis of the cactus alkaloids.”
Kapadia & Fayez (1970) cited “Kapadia, Rao, Leete, Fayez, Vaishnav and Fales, to be published.” i.e. Kapadia et al. (1970)b Journal of the American Chemical Society 92 (23): 6943-6951.
(trace: Kapadia et al. 1970)

O-Methylpeyoxylic acid

mp, NMR
Kapadia et al. (1973) Journal of Heterocyclic Chemistry, 10 (1): 135-136.
(trace: Kapadia et al. 1973)

Peyoruvic acid

gc
Kapadia et al. (1970)b Journal of the American Chemical Society, 92 (23): 6943-6951.
(trace: Kapadia et al. 1970)

O-Methylpeyoruvic acid

mp, NMR
Kapadia et al. (1973) Journal of Heterocyclic Chemistry, 10 (1): 135-136.
(trace: Kapadia et al. 1973

Mescaloxylic acid

tlc, gc-ms, synthesis, NMR, MS
Kapadia & Hussain (1972) Journal of Pharmaceutical Sciences, 61 (7): 1172-1173.
Kapadia et al. (1971) 118th Meeting of the American Pharmaceutical Association, San Francisco, California, March 27-April 2. “Some newer synthetic cactus alkaloid analogs.”
(trace: Kapadia & Hussain 1972)

Mescaloruvic acid

tlc, gc-ms, synthesis, NMR, MS
Kapadia & Hussain (1972) Journal of Pharmaceutical Sciences, 61 (7): 1172-1173.
Kapadia et al. (1971) 118th Meeting of the American Pharmaceutical Association, San Francisco, California, March 27-April 2. “Some newer synthetic cactus alkaloid analogs.”
(trace: Kapadia & Hussain 1972)

Mescaline succinamide

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
(trace: Kapadia & Highet 1968)

Mescaline malimide

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
(trace: Kapadia & Fales 1968a)

Mescaline maleimide

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689. 
(trace: Kapadia & Fales 1968a)

Mescaline citrimide

 gc-ms, and ir, nmr and ms of synthetic
Kapadia et al. (1970)a Lloydia, 33 (4): 492.
Kapadia & Fayez (1970) cite Kapadia et al. “11th Ann. Meet. Amer. Soc. Pharmacognosy (Vienna, Austria) July 1970, To be published.” i.e. Kapadia et al. (1970)a Lloydia, 33 (4): 492.
(trace: Kapadia et al. 1970)

Mescaline isocitrimide lactone

 gc-ms, and ir, nmr and ms of synthetic
Kapadia et al. (1970)a Lloydia, 33 (4): 492.
Kapadia & Fayez (1970) cite Kapadia et al. “11th Ann. Meet. Amer. Soc. Pharmacognosy (Vienna, Austria) July 1970, To be published.” i.e. Kapadia et al. (1970)a Lloydia, 33 (4): 492.
(trace: Kapadia et al. 1970)

Peyoglutam

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
(trace: Kapadia & Fales 1968a)

Mescalotam

gc-ms
Kapadia & Fales (1968)a The Chemical Society, London. Chemical Communications, 24: 1688-1689.
(trace: Kapadia & Fales 1968a)

Pyrrole derivatives:

Peyonine

 gc, ms, ir, nmr, tlc, glc, uv, mmp, synthesis
Kapadia & Shah (1967) Lloydia, 30: 287. (Proceedings.)
Kapadia & Highet (1967) Lloydia, 30: 287-288 (Proceedings.)
Kapadia & Highet (1968) Journal of Pharmaceutical Sciences, 57: 191-192.
(trace: Kapadia & Highet 1968

Peyoglunal

gc-ms, ir, nmr, ms, color reactions, synthesis
Kapadia et al. (1970)a Lloydia, 33 (4): 492.
(trace: Kapadia et al. 1970)

Other alkaloids:

Choline

tlc, gc, ir
Strongly alkaline viscous liquid. 123 mg from 2.3 kg dried peyote. 
Identified by mp and mmp of picrate and IR,
Kapadia et al. (1968) Journal of Pharmaceutical Sciences,. 57 (2): 254-262.
(0.005% dry wt: Kapadia et al. 1968

See Anderson 1980 pages 191-203 and Menachery et al. (1986) (THIQ); both have line drawings of structures. (See also Cactus Chemistry By Species)

Two other inclusions appear in some listings of peyote alkaloids:

N-(3,4,5-Trimethoxyphenethylamine)-alanine

[Synonym for Mescaloruvic acid; See Kapadia & Hussain 1972a]

 

N-(3,4,5-Trimethoxyphenethylamine)-glycine

[Synonym forMescaloxylic acid; See Kapadia & Hussain 1972a]

Do not confuse either compound with the
3,4,5-Trimethoxyphenethyl-glycine which Sethi et al. 1973 synthesized
for use as a reference standard but were unable to observe in the
plant. 

[Note:    3,4,5-Trimethoxyphenylalanine 
3,4,5-Trimethoxyphenethylglycine.]

Other compounds reported from Peyote

Serotonin was claimed in hplc by Gennaro et al. 1996. This identity was never conclusively proven and it has not been confirmed.

Glucaric acid (saccharic acid) (tlc by Kringstad & Nordal 1975).

Calcium oxalate (the forms and degree of hydration have not been established)
Users of fresh peyote have observed it as well due to it being readily perceived as sand or grit present inside of the flesh. Oxalate is sometimes present in appreciable quantities.

Rouhier 1926 observed the presence of oxalate crystals in his histological study of the plant. These are labelled “O” in the drawing below; “C” is said to indicate the shards created by the action of the microtome when making the thin section slice.
Oxalate appears to be present in the form of druses (whewellite?), crystal sand and as additional forms. Rouhier commented on “oursins d’oxalate de chaux [weddellite?] et vaisseaux spiralés” being present in the flesh in addition to “macies d’oxalate de calcium“.
Spiky crystals inside of cacti are often Weddellite (CaC2O4•2H2O) and the rounded druses Whewellite (CaC2O4•H2O) but the nature of the biominerals that exist inside of peyote flesh apparently remains unstudied. (Weddelite is extremely rare in nature outside of cacti biominerals and as a component of kidney stones but it is common in both of those.)

Alexandre-Rouhier-1926-Monographie-du-Peyotl-fig-26
Alexandre Rouhier 1926
Monographie du Peyotl, fig. 26
Oxalate crystals in peyote's flesh exposed by rodent activity
Oxalate crystals in peyote’s flesh exposed by rodent activity
 

Biosynthetic studies

Studies and route proposals for mescaline and peyote alkaloids(s):

Agurell & Lundström 1968 
Agurell et al. 1967
Basmadjian & Paul 1971
Battersby et al. 1967 
Kapadia & Fayez 1970
Khanna et al. 1969
Leete 1959 & 1966
Lundström 1971a & 1971b
Lundström & Agurell 1968b, 1969, 1971 & 1972
McLaughlin & Paul 1967
Paul 1973
Paul et al. 1969a & 1969b
Reti 1950
Rosenberg & Stohs 1974 [Comparative utilization studies for tyrosine in protein and alkaloids biosynthetic pathways. They determined the utilization of tyrosine for incorporation into alkaloids is three times the rate of incorporation into protein.]
Rosenberg et al. 1967 & 1969

Peyote alkaloids other than mescaline:

Battersby et al. 1968
Kapadia et al. 1970b
Khanna et al. 1970 [Radiolabeled precursor incorporation studies.]
Leete & Braunstein 1969
Lundström 1971c & 1972 [the latter is not a biosynthetic study per se but does offer some supportive evidence]
McFarlane & Slaytor 1972a [A point on biosynthesis of anhalonidine] & 1972b [Biosynthesis of 3,4-Dimethoxyphenethylamine]

For a review of tetrahydroisoquinolines in peyote and other cacti see pp. 256-276 in:
Jan Lundström (1983) “Simple Isoquinoline Alkaloids.” pp. 255-327 (Chapter 6) in: Arnold Brossi (Ed.) The Alkaloids. Chemistry and Pharmacology. Volume 21.
See also:
Mary D. Menachery et al. (1986) Journal of Natural Products, 49 (5): 745-778. “Simple Isoquinolines” (for a review of physical data and distribution.)

Archaic peyote, the red bean & more.

Index

At some point this index will be hotlinked and reformatted with indents and completion of the chemical names that became truncated. It is being included in this rudimentary form only to permit viewers to better be able to know the contents that are within the book. For the time being, the “search” function should be used for navigation.

The index has been updated to reflect the removal of those chapters detailing mescaline’s physical and pharmacological properties, assays and identification criteria, usage, isolations & cultivation of cacti. The contents of those chapters can be found elsewhere and will be added to this site in the future as rapidly as time permits.

 

Symbols
1,2-dimethyl-6,7-dimethoxy-8-hydroxy-3,4-dihydrois  216, 218
1-methyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoqui  216, 218
2,6-dichloro-mescaline
structure  315
2-chloro-mescaline
structure  315
2-methyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoqui  216, 218
3,4,5-trihydroxyphenethylamine
structure  314
3,4,5-trimethoxyphenethylamine  214
3,4,5-trimethoxyphenethyl-glycine  218
3,4,5-trimethoxyphenethylglycine  218
3,4,5-trimethoxyphenylalanine  218
structure  315
3,4-dihydro-6,7-diMeO-8-OH-1,2-diMe-isoquinolinium
structure  318
3,4-dihydro-6,7-diMeO-8-OH-1-Me-isoquinoline
structure  318
3,4-dihydro-6,7-diMeO-8-OH-2-Me-isoquinolinium inn
structure  318
3,4-dihydro-6,7-diMeO-8-OH-IQ
structure  318
3,4-dihydroxy-5-methoxyphenethylamine  214
structure  314
3,4-dimethoxy-b-hydroxyphenethylamine
structure  313
3,4-dimethoxy-N-methylphenethylamine
structure  313
3,4-dimethoxy-N,N-dimethylphenethylamine
structure  314
3,4-dimethoxyphenethylamine  120, 214
separation from mescaline  353
structure  313
3,5-dimethoxy-4-hydroxyphenethylamine  126, 131
3-b-Hydroxy-11a,12a-epoxyoleanan-
28,13B-olide  322
3-hydroxy-4,5-dimethoxyphenethylamine  214
structure  314
3-hydroxy-4-methoxyphenethylamine
structure  313
3-methoxytyramine  103, 120, 214
structure  313
3-nitrotyramine
structure  314
4-hydroxy-3,5-dimethoxyphenethylamine
structure  314
4-hydroxy-3-methoxyphenethylamine  214
4-methoxy-b-hydroxyphenethylamine
structure  312
4-methoxyphenethylamine
structure  312
6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinoline  216, 218
7-hydroxy-6-methoxy-2-methyl-THIQ  120
56.1153  350
60.0450  412
1046  412
53086  425
A
abbreviations  7
Aberle, David Friend  360
abstracts of useful manipulations  352
Acacia  167
amentacea  166
spp  167
acetic acid  392
acetone  392
acetonitrile  392
Acharagma aguirreana  94
Adavasio & Fry 1976  219
Agave lechuguilla  167
Aguas Calientes  165
Akers, John Frank  360
Alamosenogenin  322
Albert I, Prince  360
alkaloid biosynthesis
studies  219
alkaloid cross-list  446
Amberlite IRA 401  352
amphetamine
structure  312
amulet  155
amyrin
structure  322
Ancash  351
Anderson, Edward (“Ted”) F.  360
anhalamine  111, 113, 114, 115, 116, 117, 131, 134, 138, 139, 143, 215, 218
effects  213
structure  317
anhalidine  103, 111, 113, 114, 115, 116, 117, 119, 131, 134, 138, 139, 143, 215, 218
effects  213
structure  317
anhalinine  111, 113, 114, 115, 116, 117, 119, 131, 134, 138, 139, 215, 253, 255, 256, 257, 258
structure  317
anhalonidine  111, 113, 114, 115, 116, 117, 119, 131, 134, 138, 139, 143, 215, 218, 253, 255, 256, 257, 258
effects  211
structure  317
anhalonine  111, 114, 115, 116, 117, 119, 131, 134, 138, 139, 216
effects  213
structure  317
Anhalonium
jourdanianum  139
lewinii  150
botanical drawing  122
williamsii  121, 150
Heffter’s image  (= Lophophora diffusa)  122
anhalotine  215
structure  318
Anonymous 1959  206
antiseptic  155
Appendices  358
Appleseed
Johnny  360
archaeological study  219
Arechavaleta
José  360
Arendt
Paul  360
Arequipa  120
arizonine
structure  316
Armatocereus
laetus  273
Arp
Gerald Kench  360
a-spinasterol
structure  322
Atropa belladonna  152
Austrcylindropuntia cylindrica  231
ayahuasca
songs  225, 226
azee  150, 151
azee’ chíÌidii  150
azee’ diyinÌ  150
azee’ yitíaalii  150
Aztekium ritteri  93, 103
entry  103
B
Backeberg, Curt  360
backebergine
structure  316
bac·noc  150
bad seed  150
Bailey
Liberty Hyde  360
b-amyrin
structure  322
Baum, Bernard Rene  360
bee-sugar  150
Bennett, Wendell Clark  360
Benson, Lyman David  360
Benson 1972  280
benzene  392
betalains  111
betulin
structure  322
betulinic acid
structure  322
beyo  150
b-hydroxy-mescaline
structure  315
bibliographic database
suggestion for creating  225
biisung  150
biote  150
biznaga  150
black-brush acacia  166
blindness  155
b-methoxy-3,4-dimethoxy-N,N-dimethylphenethylamine
structure  314
b-O-ethylsynephrine
structure  312
boiling point of solvents  392
Bolivia
53086  425
b-O-methylsynephrine
structure  312
breast pains  155
bridgesigenin
A
structure  322
B
structure  322
C
structure  322
Browningieae  94
Bruhn et al. 1978  220
Bruhn et al. 2002  220
Bruhn & Holmstedt 1974  123, 136, 206, 220
bruises  155
b-sitosterol
structure  322
butanol  392
button  151, 204, 221, 275
C
Cacavalia cordifolia  152
Cactaceae  93, 94
Cacteae  93, 94
cacti containing mescaline  93
Cactinae  93
cactus  150
alkaloid crosslisting  446
buttons  150
cactus-pudding  150
cactus sand  204
caffeine  103
calenduladiol
structure  322
calipamine
structure  313
calycotomine
structure  317
camaba  150, 151
campesterol
structure  322
candicine  213
structure  312
carbon tetrachloride  392
Carnegiea gigantea  260
carnegine
structure  317
carrot  152
Castela texana  166
Catamarca  104
Catarina-Copita  155
Catorce  165
Cephalocereus melanostele  260
Cephalocereus sp  260
Cereinae  93
Cereoideae  93
Cereus
acranthus  260
peruvianus  260
sp  260
Cerro de Peotillos  165
challote  150
Chapter  1  29
Endnotes  56
Chapter  2  77
Chapter  3
endnotes  276
Chapter  7  101
Chapter 10  350
endnotes  357
Chapter 13  358
Charalampous et al. 1966
isolation abstract  354
Charles Grimaldi  360
charm  155
chaute  150
chewing medicine  151
chichipegenin
structure  322
chiculi hualala saeliami  154
chiee  150, 151
chief  150
chief peyote  154
Chihuahua  165
childbirth  155
chin cactus  104
chloroform  392
cholestane
structure  322
cholestanol
structure  322
cholesterol
structure  322
choline  142
Chubul  107
ciguri  150
Coahuila  165, 219, 206, 126, 219
Cochabamba  110
cochalic acid
structure  322
Coldenia canescens  167
colds  155
collection numbers
database  307
Knize  299
Ritter  307
collection scene  74
colorin  220
comarapa  107
Condalia spp  167
Copita  155
coryneine
structure  313
corypalline  120
structure  316
Coryphantha
macromeris  260
palmeri  260
runyonii  260
scolymoides  260
spp  167
Coryphantha scolymoides  270
coryphanthine
structure  312
cramps  155
creosote bush  167
crest  411
Cretaceous  155
cristate
Trichocereus bridgesii
monstrose  377, 444
Crosby & McLaughlin 1973
isolation abstract  353
crosslisting of alkaloids  446
crucifixion thorn  167
Cuatro Cienegas  219
cuts  155
cyclohexane  392
cyclostenol
structure  322
Cylindropuntia
acanthocarpa  229
imbricata  233
spinosior  234
Cylindropuntiae  93
D
DCM  393
deglucopterocereine
structure  318
deglucopterocereine-N-oxide
structure  318
dehydroheliamine
structure  316
dehydrolemaireocereine
structure  316
dehydronortehuanine
structure  318
dehydronorweberine
structure  319
dehydropachycereine
structure  319
dehydrosalsolidine
structure  316, 317
DeSmet  & Bruhn 2003  220
devil’s root  150
devil medicine  151
diabetes  155
diabolic root  150
dichlor  393
dichloromethane  393
dielectric contants  392
diethylamine  392
diethyl ether  392
dimethylamine  392
dimethylformamide  392
dimethylsulfoxide  392
dioxane  392
distribution of peyote  80
divine cactus  150
divine herb  150
DJF  377
DMPEA  353
DMSO  392
Donnan & Mackey 1978  280
dopamine  214, 313
Dowex 50 W-X4  354
dream buttons  150
druses  204
dryness and alkaloids  206
dry whisky  150, 154
dumortierigenin
structure  322
dumpling cactus  150
Durango  165
DyidÈ  16
E
eagle’s claw cactus  167
ear-eating  154
echinata  139
Echinocactinae  93
Echinocactus horizonthalonius  167
Echinocactus jourdanianus  139
Echinocactus schmiedickeanus  256
Echinocactus williamsii a pellotinica  121
electrophoresis of mescaline  355
El-Seedi et al. 2005  220
elution
suggested order  392
Endnotes
background & perspective  56
Ch  1  56
Ch  3  276
Ch 10  357
mescaline
occurrences  276
occurrence of mescaline  276
opening comments  24
solvent properties table  394
useful manipulations  357
enema use  280
epinephrine
structure  313
epinine  214, 313
Epiphyllum sp  260
epithelanthate
structure  323
errors  260
erynginol A
structure  323
Erythrina flabelliformis
seed  220
erythrodiol
structure  323
ethanol  392
ether  392
ethyl acetate  392
Euphorbia antisyphilitica  167
F
Father Peyote  151
field collection #
database  307
Knize  299
Ritter  307
fish-hook  167
flash point of solvents  392
Flourensia cernua  167
flower  150
foutouri  150
FR 17  307
FR 26  307
FR 70  307
FR 72  307
FR 101  307
FR 155  307
FR 155a  307
FR 156  307
FR 270  307
FR 270a  307
FR 567  307
FR 567a  307
FR 615  307
FR 676  307
FR 677  307
FR 677a  307
FR 853  307
FR 856  307
FR 991  307
FR 993  307
FR 994  307
FR 1467  307
FR 1468  307
fractures  155
friedelan-3a-ol
structure  323
friedelin
structure  323
frogs  211
Fujita et al. 1972  218
funnels  280
Furst on ancient peyote  220
G
Garceno  155
ghost medicine  151
gicuri  150
gigantine
structure  317
globulars  119
glucaric acid  103, 134, 218
GR 1086  138
Grandfather Peyote  154
green whiskey  150
Grimaldi
Albert Honoré Charles  360
grippe  155
gummosogenin  323
Gymnocactus aguirreanus  94
Gymnocactus beguinii  261
Gymnocalycium achirasense  93, 104, 112
analysis  111
Gymnocalycium asterium  93, 104
analysis  111
var. paucispinum  111
Gymnocalycium baldianum  93, 104, 105
analysis  111
entry  104
Gymnocalycium calochlorum  93, 104, 105, 106
analysis  113
entry  105
Gymnocalycium carminanthum  93, 104
analysis  113
Gymnocalycium comarapense  93, 104
analysis  113
entry  107
Gymnocalycium denudatum  93, 104
analysis  113
Gymnocalycium fleischerianum  104, 261
analysis  113, 114
Gymnocalycium gibbosum  93, 104, 114
analysis  114
cv. schlumbergii  108
entry  107
var. gibbosum  107, 108
water content  114
Gymnocalycium guerkeanum  110
Gymnocalycium horridispinum  93, 104
analysis  114
entry  108
Gymnocalycium leeanum  93, 104, 108, 109, 114
analysis  114
entry  108
Gymnocalycium mesopotamicum  93, 104
analysis  114
Gymnocalycium monvillei  93, 104
analysis  115
Gymnocalycium moserianum  93, 104
analysis  115
Gymnocalycium multiflorum  109
entry  109
Gymnocalycium netrelianum  93, 104
analysis  115
entry  109
Gymnocalycium nigriareolatum  93, 104
analysis  115
Gymnocalycium oenanthemum  93, 104, 115
analysis  115
Gymnocalycium paraguayense  93, 104
analysis  116
Gymnocalycium platense  119
Gymnocalycium quehlianum  93, 104, 116
analysis  116
Gymnocalycium ragonesii  93, 104
analysis  116
Gymnocalycium riograndense  93, 104, 110, 116
analysis  116
entry  110
Gymnocalycium riojense  104, 261
analysis  116
Gymnocalycium species
analysis reported  111
entry  104
Gymnocalycium stellatum  93, 104
analysis  116, 117
Gymnocalycium striglianum  93, 104
analysis  117
entry  110
Gymnocalycium triacanthum  93, 104, 117, 118
analysis  117
Gymnocalycium uebelmannianum  93, 104
analysis  117
Gymnocalycium uruguayense  110
Gymnocalycium valnicekianum  93, 104, 110, 117
analysis  117
entry  110
Gymnocalycium vatteri  93, 104, 111, 119
analysis  119
entry  111
H
H 53086 Bolivia  425
hahaayanx  150
hair  226
Hamatocactus spp  167
hatzimouika  154
HCl gas  354
healing wash  155
heliamine
structure  316
hemorrhages  155
heptane  392
hexane  393
hiccoughs  155
hicoli  150
hicore  150
hÌcori  150
hÌcouri  150
hÌculi  150
hÌcuri  150
hÌkoli  150
hÌkori  150
hik˙ri  150
hÌkuli  150
hÌkuli houanamÈ  154
hÌkuli wal˙la s‰lÌami  154
hi-kuri  150
hÌkuri  150
hÌkurÌ-ÌkurÌwa  154
hi-kuri owa-me  154
hi-kuri waname  150, 154
hi-kuri waru-ra seriame  154
hi-kuri wikara-re  154
Hildago  165
ho  150
ho-as  150
hogim·  154
Holy medicine  151
hoos  150
hordenine  103, 111, 113, 114, 115, 116, 117, 119, 120, 126, 131, 134, 138, 139, 213, 253, 254, 255, 256, 257, 258
effects  211
structure  312
hos  150
ho-se  150
houanamÈ  150
houatari  150
houtari  150
huaname  150
Huarochiri  89
huatari  150
human urine
recovering mescaline  354
huÒka  150
hus  150
Hutchison 543  89
Hutchison 1046  412
hydrocotarnine
structure  317
hydrohydrastinine
structure  317
I
icaros  225, 226
icuri  150
iguana  280
indian dope  150
infections  155
influenza  155
Inquisition law  227
intestinal ills  155
ion-exchange resin  352
IPA  393
i-propanol  393
ISBN
San Pedro  409
Some simple tryptamines  409
ISI 98-20  425
Islaya minor  93
entry  120
isoanhalamine  215
structure  317
isoanhalidine  215
structure  317
isoanhalonidine  215
structure  317
isobackebergine
structure  316
isonortehuanine
structure  318
isonorweberine
structure  319
isopachycereine
structure  319
isopellotine  215
structure  317
isopropanol  393
isoquinoline
key to structural table  315
isoquinolines
structure table  316
isosalsolidine
structure  317
isosalsoline
structure  316
J
Jalisco  165
Jardin Exotique, Monaco 3487  412
Jatropha dioica  167
jÌcoli  150
jÌcori  150
jÌculi  150
jicuri  150
jicurite  150
jÌkuli  150
jÌkuri  150
Jimenez-Quemado  155
Johnson, Harry S.  350
joutori  150
K
kamaba  150
kamba  150
key to structural tables  315
Kimnach et al. 2760B  425
KK242  395
KK2151  307
KK2152  307
KK2175  307
KK2176  307
Knize  396
Kobuki-ubadama  143
Koeberlinia spinosa  167
Krebs acid conjugates  321
Krebs cycle conjugates
structure  321
kÛp  150
L
La Plata  107
Larrea tridentata  167
Las Tablas  252
LD50
solvents  392
leather plant  167
lechuguilla  167
lemaireocereine
structure  316
Lemaireocereus laetus  273
likuri  150
liquor head  154
longimammamine
structure  316
longimammatine
structure  316
longimammidine
structure  316
longimammine  312
longimammosine
structure  316
longispinogenin  323
lophenol
structure  323
lophocereine
structure  317
Lophophora
fricii
flowering  129, 419
possible hybrids  145
sp. Parras  129, 419
Lophophora decipiens  140, 142
entry  143
type specimen  139
Lophophora diffusa  93, 121, 122, 123, 124, 417
analysis reported  134
& Anhalonium williamsii  122
entry  121
flower  123
seedlings  123
var. koehresii  134, 136
analysis reported  126
entry  126, 133
flower  134
Lophophora echinata
crest  411
Lophophora fricii  93, 126, 127
flower  126, 127, 129, 419
flowering  125
Lophophora jourdaniana  93, 131, 132, 421, 427, 428
analysis reported  139
entry  130
fruit  130
Lophophora koehresii  93
Lophophora species
no labels  422
Lophophora williamsii  7, 10, 29, 83, 84, 93, 151, 152, 151, 182, 155, 216, 205, 227, 210, 101, 358, 102, 182, 413, 417, 422
87 year old  206
alkaloid biosynthesis
studies  219
alkaloid content  205
seasonal fluctuations  206
alkaloids identified  213
analysis
ancient  219
analysis reported  204
ancient  219
archaeological recovery  219
Australia  150
cactus sand  204
cultivation in closet  227
description  176
distribution  155
distribution map  80
druses  204
eaten  206
echinata  90, 139, 153
entry  150
etymology  150
f. caespitosa  137
first illustration  145
flower  430
flowering  87
folk use  155
grafted  83, 84, 358, 417
hair  226
in habitat  95, 96
Inquisition Law  227
mescaline content  204
impact of water deprivation  206
mummified  220
music  225, 226
name meaning  150
occurrence  80, 155
oxalate druses  204
percentage of alkaloid reported  207
peyote button  204, 221, 275
pollen  195
radiocarbon dating  219
regrowth after harvest  176, 208
sacramental history  155
scale insects  87
seasonal fluctuations  206
songs  225, 226
spines  131, 163, 181, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 196, 197, 198, 202, 203, 433
suggested reading  223
var. caespitosa  216, 138, 216, 138, 222
analysis reported  218
entry  143
var. decipiens  142, 145
analysis reported  218
var. echinata  8, 93, 182, 146
var. pentagona  142
analysis reported  218
var. texensis  143
var. typica  214
analysis reported  219
var. williamsii  182
weightlifting  1
williamsii  147, 149
lophophorine  111, 114, 115, 116, 117, 119, 131, 134, 138, 139, 143, 216, 218
effects  211
separating from mescaline  353
structure  317
lophotine  216
structure  318
lotebush  167
L.S.D. cactus  150
LSD cactus  154
lupenetriol
structure  323
lupeol
structure  323
M
macdougallin
structure  323
machaeric acid
structure  323
machaerinic acid
structure  323
Machaerocereus eruca  73
macromerine  260
structure  314
makan  150
Mammillaria  154
Mammillaria spp  167
Marini-BettÚlo & Coch Frugoni 1958
electrophoresis of mescaline  355
Martin, Ralph  307
Matucana  11, 12
Maverick  155
McLaughlin & Paul 1966
isolation abstract  352
McLaughlin & Paul 1967
isolation abstract  285
medicine  150
medicine of god  150
medizin  150
MEK  393
Melocactus  119
Melocactus peruvianus  261
Mendoza  107
mescal  150, 154
mescal bean  150
mescal button  150
mescale  150
mescaline  103, 111, 113, 114, 115, 116, 117, 119, 120, 126, 131, 134, 138, 139, 214, 218, 219, 253, 255, 257, 258
3,4-dimethoxyphenethylamine, separation from  353
citrimide  217
structure  321
electrophoresis  355
erroneous reports  260
errors  260
isocitrimide lactone  217
structure  321
lophophorine, separating from  353
maleimide  217
structure  321
malimide  217
structure  321
occurrence list  93
pellotine, separating from  353
preparative tlc  354
questionable  260
structure  314
succinamide  217
structure  321
trace reports  260
mescaline containing species  89
mescalito  150
mescaloruvic acid  217, 142
structure  321
mescalotam  142
structure  318, 321
mescaloxylic acid  217, 142
structure  321
mesquite  167
metanephrine
structure  313
methamphetamine
structure  312
methanol  393
methyl betulinate
structure  323
methylene chloride  393
methyl epithelanthate
structure  323
methyl ethyl ketone  393
methyl machaerinate
structure  323
methyl oleanolate
structure  323
methyl queretaroate
structure  323
Mexican buckeye  222
mezcal buttons  150
Mitragyna africana  16
Moche
collection scene  74
Moche ceramic  280
Mollendo  120
monstrose
Trichocereus bridgesii  445
moon  150, 152
moon pods  152
mother hurimoa  154
mummified peyote  220
Murrah Cave  220
Musacchio & Goldstein 1967
isolation abstract  354
muscale buttons  150
music
peyote  225, 226
Myrtillocactus geometrizans  261
myrtillogenic acid
structure  323
N
N-(3,4,5-trimethoxyphenethylamine)-alanine  142
N-(3,4,5-trimethoxyphenethylamine)-glycine  142
N-acetyl-3-demethylmescaline  214
N-acetyl-3-hydroxy-4,5-dimethoxyphenethylamine  214
structure  314
N-acetylanhalamine  215
N-acetylanhalonine  217
N-acetyl DMPEA
structure  313
N-acetylmescaline  215
structure  315
NAMT
structure  313
nat·inoni  150
naw-tai-no-nee  150
Neolloydia schmiedickeanus var. schwarzii  258
Neolloydia spp  167
Neoraimondia macrostibas  261
nesac  150
Newcomb, WW  220
nezats  150
N-formyl-3-demethylmescaline  214
N-formyl-3-hydroxy-4,5-dimethoxyphenethylamine  214
structure  314
N-formylanhalamine  215
N-formylanhalinine  215
N-formylanhalonidine  215
N-formylanhalonine  217
N-formylmescaline  215
structure  314
N-formyl-O-methylanhalonidine  216
Nickels, Anna B.  210
nicouri  150
nihook’eh doo bÌnii’oh  154
ni’iln’ÌÌ’ sizÌnii  154
nipple cactus  167
N-methyl-3,4-dimethoxyphenethylamine  126, 131, 214
N-methyl-3-hydroxy-4,5-dimethoxyphenethylamine  214
structure  314
N-methyl-3-methoxytyramine
structure  313
N-methyl-4-hydroxy-3-methoxyphenethylamine  214
N-methyl-4-methoxyphenethylamine
structure  312
N-methyl-6,7-dimethoxy-isoquinolinium chloride
structure  318
N-methylheliamine
structure  316
N-methylisosalsoline
structure  317
N-methylmescaline  111, 113, 114, 115, 116, 117, 119, 126, 131, 134, 138, 139, 214, 253, 255, 256, 257, 258
structure  314
N-methylmetanephrine
structure  313
N-methyl-pachycereine
structure  319
N-methylphenethylamine
structure  312
N-methyltyramine  103, 111, 113, 114, 115, 116, 117, 119, 120, 126, 131, 134, 138, 139, 213, 253, 255, 256, 257, 258
structure  312
N,N-dimethyl-3,4-dimethoxyphenethylamine  103
N,N-dimethyl-3-hydroxy-4,5-dimethoxyphenethylamine  214
structure  314
N,N-dimethyl-3-methoxy-4-hydroxyphenethylamine  131
N,N-dimethyl-3-methoxytyramine
structure  313
N,N-dimethyl-4-hydroxy-3-methoxyphenethylamine  214
N,N-dimethyl-4-methoxy-b-hydroxyphenethylamine  312
N,N-dimethyl-4-methoxyphenethylamine  312
N,N-dimethylmescaline  111, 113, 114, 115, 116, 117, 253, 255, 256, 258
N,N-dimethylphenethylamine
structure  312
nonc-g·ien  150
norepinephrine  313
normacromerine  260
structure  313
normetanephrine
structure  313
nortehuanine
structure  317
norweberine
structure  319
Notocacteae  94
n-propanol  393
Nuevo Leon  103
Nuevo LÈon  165
O
occurrence of peyote  80
octopamine
structure  312
o-jay-bee-kee  150
oleanolic acid
structure  324
oleanolic aldehyde
structure  324
ololiuqui  150
O-methyladrenaline
structure  313
O-methylanhalidine  111, 113, 114, 115, 116, 117, 131, 134, 138, 139, 253, 255, 256, 257, 258
O-methylanhalonidine  113, 114, 115, 116, 117, 215
structure  317
O-methylcandicine  312
O-methylcorypalline
structure  316
O-methylpellotine  131, 134, 136, 216
structure  317
O-methylpeyoruvic acid  217
structure  318
O-methylpeyoxylic acid  217
structure  318
Opuntia  93
Opuntia acanthocarpa  93
Opuntia atrispina
companion  175
Opuntia basilaris  93
Opuntia echinocarpa  93
Opuntia ficus-indica
Australia  92
Opuntia imbricata  93
Opuntia leptocaulis  167
Opuntia pachiypus  261
Opuntia sp  261
Opuntia spinosior  93, 353
Opuntieae  93
Opuntioideae  94
Ostolaza 1998  280
owa-me  154
oxalate druses  204
P
P  150
pachanol A
structure  324
Pachycereeae  94
pachycereine  319
pajÈ  150
Pang 1992  280
paralysis  155
Pardanani et al. 1978
isolation abstract  353
Parras  129, 419
partially eaten peyote  206
pee-yot  150
peiotl  150, 152
pejori  150
pejote  150
pejuta  150
Pelecyphora aselliformis  93, 423
pellote  150
pellotine  103, 111, 113, 114, 115, 116, 117, 119, 120, 131, 134, 138, 139, 143, 215, 218, 219, 253, 255, 256, 257, 258
effects  211
methiodide  215
separating from mescaline  353
structure  317
pencil cactus  167
penicillin resistant bacteria  212
peniocerol
structure  324
pentane  393
peodi  150
peote  150
peotl  150
percentages of alkaloids
chronology of alkaloid identification  209
effects  212
nonmescaline alkaloids
pharmacological overview  211
Pereskia corrugata  93
Pereskia tampicana  93
Pereskieae  93
Pereskioideae  94
Pereskiopsis scandens  93
Peru 56.1153  350
Peru 60.0450  412
peyiotl  150
peyocactin  212
peyoglunal  142
structure  321
peyoglutam  142
structure  318, 321
peyonine  142
structure  321
peyophorine  217
structure  318
peyori  150
peyoruvic acid  217
structure  318
peyot  150
peyote button  204, 221, 275
peyote crisis  77, 79
peyote harvests  78
peyote medicine  154
peyote music  225, 226
peyote woman  154
peyotine  143, 215
structure  318
pÈyotl  150
peyotlevye  150
peyotlkaktus  150
peyotl of the goddesses  154
peyotl of the gods  154
pÈyotl zacatecensis  150
peyotyl  150
peyoxylic acid  217
structure  318
pezote  150
phenethylamine  120, 253, 255, 256, 257, 258
key to structural table  315
structure  312
phenethylamines
structure table  312
pilocereine
structure  319
piote  150
piotes  212
piotl  150
piule  150
pi.yot  150
pneumonia  155
Poisson 1960
isolation abstract  355
polarity index  392
Polaskia chende  93, 9
Porlieria angustifolia
flower  169
PR 3293  138
preparative tlc  354
Prince Albert I  360
propanol  393
Prosopis laevigata  167
protection  155
pterocereine
structure  317
Pterocereus gaumeri  93
pulmonary issues  155
pycnarrhine
structure  318
pyridine  393
Q
Quepo  280
Queretaro  254
QuerÈtaro  121, 165
queretaroic acid
structure  324
queretarol
structure  324
questions  260
quinic acid  103, 134
R
raÌz diabÛlica  150
Ratsch 1998  280
rat urine
recovering mescaline from  354
Rauschgiftkaktus  150
Reading suggestions  374
Real del Catorce  165
red bean  220
Requirement  41
Reynosa  155
RhaÔtoumuanitarihua-hicouri  154
rheumatism  155
RÌo Chubut  107
RÌo Negro  107
Rio Rimac  89
Ritter
field collection #  307
rock lifting
peyote  1
Rosenberg et al. 1967
isolation abstract  352
Rouhier 1927  80
RS0003  395
S
Sacred Cacti
covers  2
sacred mushroom  150
salicifoline
structure  313
Salomon et al. 1949
isolation abstract  355
salsolidine
structure  316
salsoline
structure  316
salsolinol
structure  316
San Luis  107
San Luis Potosi  252, 254, 257, 258
San Luis PotosÌ  155, 165, 206
San Pedro  273
ISBN  409
Santa Rita  257
scaling up  357
scarlet fever  155
Schnapskopf  150, 154
schneckenwesen  280
scorpion stings  155
sei  150
Seimayi  154
seni  150
seÒi  150
Shumla Cave  219
Sierra de CÛrdoba  107
sitosterol
structure  322
skin diseases  155
snake-bite  155
solubility of solvents  392
solvent hazards  392
solvent properties  392, 393
table  392
endnotes  394
Some simple tryptamines
ISBN  409
songs
peyote  225, 226
Sonora  165
Sophora secundiflora  152, 222
flowering  218
seed  220
seedpods  219
sores  155
spasms  155
spinasterol
structure  322
spines on peyote  131, 163, 181, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 196, 197, 198, 202, 203, 433
SS02  90
Standard  414
Staphylococcus aureus  212
Staphylococcus pyogenes  212
stellatogenin
structure  324
stenocereol
structure  324
Stenocereus beneckei  93
Stenocereus eruca  93, 246
Stenocereus hystrix  271
Stenocereus stellatus  93
Stenocereus treleasei  93, 249
Stetsonia coryne  93
stigmasterol
structure  324
stimulant  155
Strombocactus lophophoroides  252
Strombocactus pseudomacrochele  254
var. krainzianus  254
Strombocactus schmiedickeanus  256
Strombocactus schwarzii  258
structure table
isoquinolines  316
phenethylamines  312
triterpenoids  322
strychnine-like  211
sugar  150
suggested reading  374
superior peyote  154
supernatural protection  155
swooning  155
synephrine
structure  312
T
table of contents  5
taraxerol
structure  324
taraxerone
structure  324
tarbush  167
Taumaulipas  155
Taylor 1941  220
tehuanine
structure  317
tehuanine-N-oxide
structure  317
teocomitl ahuitzyo  150
teonanacatl  150, 151
tepenine
structure  317
Terry et al. 2005  219
tetrahydrofuran  393
Texas mountain-laurel  222
Thelocactus lophophoroides  252
THF  393
thurberin
structure  324
thurberogenin
structure  324
thurberol
structure  324
TJG. See Juul’s Giant
Todd 1969  134, 205
isolation abstract  352
toluene  393
tonic  155
toothache  155
topi  150
tops  151
Toumeya krainziana  254
Toumeya lophophoroides  252
Toumeya pseudomacrochele  254
Toumeya schmiedickeanus  256
Toumeya schwarzii  258
traces  260
treleasegenic acid
structure  324
Trichocereeae  94
trichocereine
structure  315
Trichocereus
aff. bridgesii  319
aff. huanucoensis  93
Trichocereus bridgesii  93, 307
HBG  28
monstrose  13, 93, 445
crest  377, 444
cristate  377, 444
SS02  90
Trichocereus cephalomacrostibas  261
Trichocereus crassicostatus  307
Trichocereus cuzcoensis  93, 307, 477
Trichocereus cv.
Lumberjack  277
Trichocereus fulvilanus  14, 93, 377
Trichocereus glaucus  307, 395
Trichocereus huanucoensis  93, 423
Peru 56.1153  350
Trichocereus knuthianus  307
Trichocereus macrogonus  93
pup  478
Trichocereus pachanoi  93, 307, 418
compared to
pachanoi Ecuador  420
Ecuador  420
flowering  4
monstrosus  93
Peru  4
typical  418
Trichocereus pallarensis  93, 307, 93
forma Machac  307
Trichocereus peruvianoid  396
Trichocereus peruvianus  93, 353, 307, 424
Ancash  351
flower  3
Hutchison 543  89
in habitat  11, 12
KK242  395
Knize  396
Matucana  11, 12
monstrosus  93
RS0003  395
Trichocereus puquiensis  93
monstrosus  93
Trichocereus riomizquiensis  307
Trichocereus santaensis  93, 307, 93
Trichocereus scopulicola  93, 307, 73
Trichocereus sp
Juul’s Giant  93
SS03  426
Standard  414
Trichocereus strigosus  93
Trichocereus tacaquirensis  307
Trichocereus tacnaensis  307
var Estique  307
Trichocereus taquimbalensis  93, 425
in habitat  98
Trichocereus tarmaensis  412
Trichocereus terscheckii  93, 307
Quebrada del toro  377
Trichocereus terscheckioides  307
Trichocereus thelegonoides  93
Trichocereus torataensis  307
Trichocereus tulhuayacensis  261
Trichocereus uyupampensis  93, 412
Trichocereus validus  30, 93
Trichocereus vollianus  93
Trichocereus werdermannianus  93, 307
triterpenoids
key to structure table  325
structural table  322
structure table  322
tuberculosis  155
tuna de tierra  150
Turbinicarpus
entry  252
Turbinicarpus flaviflorus  252, 257
Turbinicarpus krainzianus  254
Turbinicarpus lophophoroides  93, 253
entry  252
Turbinicarpus pseudomacrochele  254
entry  254
var. krainzianus  93, 254, 255
entry  254
f. minimus  255
Turbinicarpus schmiedickeanus
entry  256
ssp. dickisoniae  257
var. flaviflorus  93, 257
entry  257
var schmiedickeanus  256
var. schmiedickeanus  256
var. schwarzii  93
entry  258
Turbinicarpus schwarzii  258
Turner & Heyman 1960
isolation abstract  353
turnip cactus  150
tyramine  111, 113, 114, 115, 116, 117, 119, 120, 126, 131, 134, 138, 139, 213, 253, 255, 256, 257, 258
structure  312
tzinouritehua-hicouri  154
U
ubadama  150
uberine
structure  316
ubine
structure  312
Ungnadia speciosa  219
uocoui  150
urine
recovering mescaline  354
V
venereal diseases  155
Viesca/Vieska  131
VizarrÛn  121, 134, 136
W
walena  150
waname  150
wanamo  150
wanamu  150
watara  150
water  393
wax plant  167
weberidine
structure  316
weberine
structure  319
weightlifting
Lophophora williamsii  1
w gwe i-a  151
whiskey barrel cactus  150
whiskey cactus  150
whiskey root  150, 154
whisky cactus  154
white mule  150, 154
William’s aloÎcactus  150
Williams, C.H.  150
witchcraft  155
wo-co-wist  150
wohoki  150
wokow  150
wokowi  150, 151
wokwi  150, 151
wonderful herb  150
woqui  150
wounds  155
X
xÌcori  150
xucladjin-dei  150, 152
xwucdjuyahi  150
xylene  393
Y
yucca  167
Yucca filifera  167
Z
Zacatecas  165
Zapata  155

Turbinicarpus

The Turbinicarpus species

 

These plants are miniature cacti occurring in the Mexican Chihuahuan Desert.
They are often grafted to produce faster growth and increased offsets for propagation. Grafting similarly increases the rate and occurrence of flowering.
Extremely easy to grow from seed. Ready sets viable seed even in cultivation or in grafted plants.
Fruit dehisces via a single longitudinal split.
The dull colored fruit are said to not be attractive to birds and other animals that could help spread seeds.
Distribution is apparently via ants, wind and water; producing a limited range for these tiny plants.
Many different collection numbers exist in horticulture.
They are very popular among cactus collectors due to their small adult size, free flowering and generally overall wonderful appearance.
So much so that some have been entirely wiped out of their native habitat to fill the demand of collectors.
In at least one case where a new species was described, its extremely limited native habitat was immediately collected down to the last locateable plant by commercial European cactus collectors. All were apparently shipped elsewhere for resale to collectors who value possessing very rare plants.
They are EASY to grow from seed.

The published names have included not just several other genera (Echinocactus, Neolloydia, Pediocactus, Strombocatus, Thelocactus & Toumeya) but they have also been variously reshuffled as varieties and subspecies of each other.  
Lining up the actual species that were tested by Štarha with what is recognized as those species may not be accurate due to those repeated revisions. In those areas with discrepancies it is best to weight in on the side of European views rather than those coming from authors in the USA as Štarha relied on European seed sources for producing his material.
All Turbinicarpus species analyzed by Dr. Štarha were seed grown in Czechoslovakian greenhouses.

Etymology:
Turbinicarpus was named for its top-like fruit (“turbinate“) It is a “bastard” word combining the Latin word “turbineus“, meaning “top“, with the Greek word for fruit “karpos“.
Echinocactus was named for being perceived of as resembling a hedgehog. From the Greek words echinos (hedgehog) and kaktus (thistle or artichoke).
Neolloydia was named after the botanist Francis Ernest Lloyd (4 October 1868 – 10 October 1947).
Pediocactus was derived from the Greek word pedion referring to its habitat being on the “plains“.
Strombocactus is from the Greek word strombos meaning “fir-cone” or “a spinning top” or “shell-shaped” in reference to its shape.
Thelocactus  came from the Greek word thelo meaning “wart” or “nipple” referring to the sharply defined and pronounced tubercles.
Toumeya was coined to honor Dean James W. Toumey of New Mexico.

Biznaguita” can be found given online, without a reference, as a common name for a number of the Turbinicarpus species but I cannot locate any primary source confirming that or, if so, which species it actually refers to. Biznaguita appears to be a generic word that is the diminutive of biznaga so it may be a general term similar to the word biznaga.

Turbinicarpus lophophoroides  (Werdermann) Buxbaum & Backeberg

Georg Werdermann (1934) Kakteenkunde, 176, as Thelocactus lophophoroides.

Franz Buxbaum & Curt Backeberg (1937) Jahrbuch der Deutschen Kakteen-Gesellschaft in der Deutschen Gesellschaft für Gartenkultur, 1: 27 (this refers to the article number – there are NO page numbers in this journal.), as Turbinicarpus lophophoroides.

Also as:
F.M. Knuth (1936) Kaktus-ABC, 356. (Strombocactus lophophoroides)
W.T. Marshall (1946) Cactus (Paris), 4: 5 & (1947) Cactus & Succulent Journal (USA), 19: 77. (Toumeya lophophoroides)

Mescaline reported as traces.

Turbinicarpus-lophophoroides-187BL

Turbinicarpus lophophoroides

Etymology: Named due to having a general resemblance to Lophophora.

Distribution & occurrence: 200 m; Las Tablas, San Luís Potosí, México (Backeberg 1977).

Habitat:  “Occurs in silty, limestone soil in dry patches in semi-swampy country where in the dry season it pulls down into the ground and is occasionally completely covered by soil” (Glass & Foster 1977).

Turbinicarpus-lophophoroides-187BR

Turbinicarpus lophophoroides

Original description:
“Simplex (ut videtur), ± hemisphaericus, ca. 2,5–3,5 cm altus et 4–4,5 cm diam., vertice dense lana albida clausus atque nonnullis aculeis laxe dispositis superatus. Costae in tuberculas 4–6 angulare, ± applanatas dissolutae. Areolae oblongae, primum breviter floccosae, dein glabrescentes. Aculei radiales 2–4, horizontaliter divaricati, ca. 4–8 mm longi, aciculares vel subsubuliformes, centralis 1, crassior, ad 1 cm longus, erectus et apicem versus incurvatus, omnes subnigri vel grisei, laeves vel subasperi. Flores e lana verticis, aperti ca. 3,5 cm diam., subalbidi. Ovarium atque tubus pallide viridia et glabra. Phylla perigonii interiora ad 2 cm longa et 4 mm lata, subacuta, albida. Filamenta fere albida. Stylus ca. 1–1,2 cm longus, albidus, stigmatibus 4, albidis multum brevior quam stamina longissima.” p. 176 in Werdermann 1934.

Generally these occur as single plants. There is a “fairly stout” taproot, Backeberg 1977.
Bluish-green (Backeberg 1977) glaucous greyish-blue to bluish-green (Glass & Foster) dull grey- or more dark green (Werdermann) Body is depressed-hemispherical (Backeberg 1977) depressed globose to flattened (Glass & Foster) rather depressed hemispherical or somewhat more conical (Werdermann), and can reach 3.5 cm high and 4.5 cm in diameter.
The crown of the plant is concealed by abundant dense, white to silvery-grey, wool or hair which is pierced through by the slightly curved spines (Backeberg & Werdermann). Grafted plants offset more freely than when on their own roots (Backeberg 1977). Anderson 1998 described stems as often being clublike and up to 2 inches wide and 4 inches tall with age.
Ribs consist of loosely packed (Werdermann) fairly flattened-rounded tubercles arranged in a spiral. They are “4-6 sided below” (Backeberg 1977), “more or less 6 angled at base, 2-4 mm high, slightly rounded, more or less 4 angled” (Glass & Foster 1977), and up to 12 mm across. They are often more or less confluent below in grafted plants (Backeberg 1977).
Areoles are somewhat elongated. They are 2.5 mm long (Glass & Foster 1977), longitudinally stretched, about 2 to 2.5 mm long, white wool when young, soon becoming bare (Werdermann).
2 or 3 (to 4) straight erect spines to 8 mm in length. One is more central than the rest and can reach 1 cm. [straight, erect to incurved, Glass & Foster]. Spines begin black or white tipped with black (Backeberg 1977). All are smooth, stiff grey to blackish or whitish with darker upper portion, slightly recurved (Glass & Foster 1977).
Whitish flower is tinged with a delicate pink color. More so towards the center and middle of the petal (Backeberg 1977).  Flowers 3.5 cm wide, tube 5 mm long, slender, pale greenish, smooth; outer perianth segments 1 cm long, 2.5 mm broad, pale yellowish green to brownish olive with pale, rounded margins; inner segments 2 cm long, 4 mm broad, white to pinkish” (Glass & Foster 1977). Light pink 1.25 inch in diameter flowers several times during the summer, Anderson 1998.
Style and 4 stigma lobes whitish (Glass & Foster 1977).
Anthers: orange yellow (Glass & Foster 1977).
Pericarp: 2-3 mm in diameter (Glass & Foster 1977).
Fruit is light green (Backeberg 1977); “occasionally with traces of vestigal scales” (Glass & Foster 1977).
Seeds are small and black.

Description adapted from:
Backeberg 1977; pages 500-501.
Glass & Foster 1977: page 171.
Werdermann 1934

Turbinicarpus-lophophoroides-187CR

Turbinicarpus lophophoroides

EM seed photo on page 170; fig. 43 of Glass & Foster 1977.

Photo on page 165; fig 13 and page 171; fig. 53 (flowering).

Photo with flowers: page 114 of Anderson 1998.
Turbinicarpus web site: http://www.mfaint.demon.co.uk/cactus/turbo/desc/lophophoroides.html includes photo of plant, flowers & seedling.

Miles Anderson describes it as being rot prone and requiring warm nights for growth during summer.
Anderson adds that it can handle 20°F for brief periods.

Turbinicarpus-lophophoroides-187TR

Turbinicarpus lophophoroides

Reported chemistry:

Phenethylamine (1.04% [± 0.27] of total alkaloid fraction of over 500 mg total alkaloids per 100 gm of fresh plant)
Tyramine (1.82% [± 0.17] of total alkaloid fraction of over 500 mg total alkaloids per 100 gm of fresh plant)
N-Methyltyramine (0.13% [± 0.11] of total alkaloid fraction of over 500 mg total alkaloids/ 100 gm of fresh)
Hordenine (91.69% [± 0.54] of total alkaloid fraction of over 500 mg total alkaloids per 100 gm of fresh plant)
Mescaline (Trace detected)
N-Methylmescaline (0.51% [± 0.11] of total alkaloid fraction of over 500 mg total alkaloids/ 100 gm of fresh)
N,N-Dimethylmescaline (Trace detected)
O-Methylanhalidine (0.55% [± 0.02] of total alkaloid fraction of over 500 mg total alkaloids/ 100 gm of fresh)
Anhalinine (0.15% [± 0.08] of total alkaloid fraction of over 500 mg total alkaloids per 100 gm of fresh plant)
Anhalonidine (2.37% [± 0.12] of total alkaloid fraction of over 500 mg total alkaloids per 100 gm of fresh plant)
Pellotine (0.46% [± 0.08] of total alkaloid fraction of over 500 mg total alkaloids per 100 gm of fresh plant)
    Štarha et al. 1999

Turbinicarpus pseudomacrochele  (Backeberg) F.Buxbaum & Backeberg

Reported chemistry:

Hordenine (Sole alkaloid. 1-10 mg of total alkaloids/ 100 gm.
fresh.) Bruhn & Bruhn 1973

Turbinicarpus-pseudomacrochele-188

Turbinicarpus pseudomacrochele

Turbinicarpus pseudomacrochele var. krainzianus  (Frank) Glass & Foster

Gerhart Frank (1960) Kakteen und Andere Sukkulenten, 11: 168, as Toumeya krainziana.
Milan Zachar (2004) The Genus Turbinicarpus, 50, as Turbinicarpus pseudomacrochele subsp. krainzianus.Also as:
Gordon D. Rowley (1974) Repertorium Plantarum Succulentarum, 8 (1972): 10 (Strombocactus pseudomacrochele var. krainzianus)
Leo Kladiwa (In Hans Krainz) (1966) Kakteen, 34: C 8 (Toumeya pseudomacrochele var. krainziana)Several additional names have appeared; those are being omitted.

 

Mescaline reported as traces.

Turbinicarpus-pseudomacrochele-v-krainzianus-188

Turbinicarpus pseudomacrochele krainzianus (SS)

Etymology: Named for Hans Krainz.

Distribution & occurrence: Mexico (It was described some 25 years after being discovered) Backeberg 1977. Glass & Foster 1977 give the distribution as “unknown, but presumed to occur in Queretaro or Hidalgo.”

Turbinicarpus-pseudomacrochele-v-krainzianus-189L

Turbinicarpus pseudomacrochele krainzianus (SS)

 

Original description:
[INSERTION STILL NEEDED]

Dark green stem is short and cylindrical. Occasionally multiheaded (Backeberg 1977). [Anderson 1998 states that it “tends to offset heavily” and forms clumps up to 6 inches across.] Heads can reach 4 cm tall and 3 cm wide (Backeberg 1977), 2-3.5 cm in diameter, 3-4 cm long (Glass & Foster 1977) [1.5 inch wide: Anderson 1998]
The crown bears white wool.
11 ribs divided into tubercles are set in spirals. The tubercles are conical above and rhomboid below.
Areoles are white and wooly. They become naked with age (Glass & Foster 1977).
6-8 flexible spines, 12-30 mm long, are more or less twisted
(tortuous). They start yellow-brown becoming grey and dark tipped and eventually drop off. [The upper spine is longest according to Glass & Foster.]

Slender funnelform flowers from apex, (Glass & Foster 1977).
Creamy yellow flower is greenish cream outside. (Backeberg 1977) Outer perianth segments are greenish with the inner segments [the petals] greenish to yellowish cream colored (Glass & Foster 1977). Flower can reach 2 cm in length.

  5/8th inch in diameter flowers in flushes; several times during summer, Anderson 1998.
Pericarp is green (Glass & Foster 1977).
Style is white with 4 white stigma lobes (Glass & Foster 1977).Ovate to globose fruit is 3-5 mm in diameter. Starts green later becomes reddish (Glass & Foster 1977).
Black seeds are 1 mm long with finely tuberculate testa (Glass & Foster 1977).

Description adapted from:
Backeberg 1961: p. 2890. Photo flowering in fig. 2721.
Backeberg 1977: page 500.
Glass & Foster 1977: page 173. Photo on page 165; fig. 16 and page 173; fig. 58 (flowering).

 

Turbinicarpus-pseudomacrochele-v-krainzianus-f-minima

Turbinicarpus pseudomacrochele krainzianus f. minima (SS)

Photo with flowers: page 114 of Anderson 1998

Miles Anderson describes it as being rot prone and needing a coarse compost.
He adds that it can handle 25°F for brief periods.

Turbinicarpus-pseudomacrochele-v-krainzianus-189

Turbinicarpus pseudomacrochele krainzianus (Mesa Garden)

Reported chemistry:

Phenethylamine (1.12% [± 0.13] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
Tyramine (0.98% [± 0.18] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
N-Methyltyramine (Trace detected)
Hordenine (49.60% [± 0.55] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
Mescaline (2.48% [± 0.19] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
N-Methylmescaline (3.27% [± 0.09] of total alkaloid fraction of 250-500 mg total alkaloids/ 100 gm of fresh plant)
N,N-Dimethylmescaline (2.89% [± 0.15] of total alkaloid fraction of 250-500 mg total alkaloids/ 100 gm of fresh plant)
O-Methylanhalidine (0.77% [± 0.04] of total alkaloid fraction of 250-500 mg total alkaloids/ 100 gm of fresh plant)
Anhalinine (29.24% [± 0.04] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
Anhalonidine (2.44% [± 0.13] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
Pellotine (0.36% [± 0.08] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
    Štarha et al. 1999

Turbinicarpus schmiedickeanus  (Bödeker) Buxbaum & Backeberg

Friedrich Bodeker (1928) Zeitschrift für Sukkulentenkunde, 3: 229, as Echinocactus schmiedickeanus.
Franz Buxbaum & Curt Backeberg (1937) Cactaceae. Jahrbücher der Deutschen Kakteen-Gesellschaft, 1: folio 27, as Turbinicarpus schmiedickeanus.Also appearing as:
J. West (1930) Cactus & Succulent Journal (USA), 2: 298 (Strombocactus schmiedickeanus).
W.T. Marshall (1946) Cactus (Paris), 4: 5 & (1947) Cactus & Succulent Journal (USA), 19: 77 (Toumeya schmiedickeana).

Mescaline reported in trace amounts.

Turbinicarpus-schmiedickeanus-HBG

Etymology: Named for Karl Schmiedicke (1870-1926).

Distribution & occurrence: La Peditas, near Miquihuana, Tamaulipas, Mexico.

Habitat: Rocky crevices in low hills. (Backeberg 1977 & Glass & Foster 1977)

Original description:
[INSERTION STILL NEEDED]

Vivid matte green (Backeberg 1977), dull green becoming gray and corky below (Glass & Foster 1977) stem is typically solitary (Glass & Foster 1977) eventually becoming shortly cylindrical (Backeberg 1977) depressed to ovate to ovate elongate (Glass & Foster 1977); to 5 cm tall and 3 cm in diameter (Backeberg 1977) to 5(-6) cm long, (2-)3 cm in diameter (Glass & Foster 1977). Grafted plants will grow larger than this (Backeberg 1977). The crown bears white wool which is overtopped by spines (Backeberg 1977).
Ribs are tuberculate and set in 8 and 13 spirals (Backeberg 1977 & Glass & Foster 1977).
Tubercles are obscurely 4-angled; 5 mm wide at base and 7 mm long (Glass & Foster 1977).
The areoles at tips of tubercles are round, white & wooly. They later become naked (Glass & Foster 1977).
3(-4) spines to 2.5 cm long. Spines curve like a ram’s horn and are bent & interlacing. they are subterete with the upper one being blade-like. They can reach 1 mm across and are flat on their upper surface (often showing a fine groove). All spines later fall off (Backeberg 1977). Spines (1-)3(-4), one to 2.5 cm long, more or less 1 mm wide, cardboardlike, curved and twisted, upper surface flattened or channeled, not rigid or pungent, gray with black tips (Glass & Foster 1977).
Pink flower with a light violet mid-stripe. Around 18 mm in diameter: Backeberg 1977. “Flower funnelform, +-2.5 cm in diameter, tube light olive green; outer perianth segments lanceolate, acute, pale dull pink with brownish mid-stripe on back; inner segments to 15 mm long, 2 mm wide, white to faint pink with cerise mid-stripe” (Glass & Foster 1977).
Fruit may have rudimentary scales or be naked (Backeberg 1977). Fruit is naked and dehisces along a single longitudinal split (Glass & Foster 1977).
Stigma has 5 whitish to pale yellowish lobes (Glass & Foster
1977).

Anthers are whitish to pale pink (Glass & Foster 1977).
Seeds are small, black and rough verrucose (Glass & Foster 1977).

Description adapted from:
Backeberg 1977; page 501,
Glass & Foster 1977.

EM seed photo on page 170 of Glass & Foster 1977.
Photo on page 162; fig. 3 (seedling), page 164; fig. 7, page 166; fig. 19 and page 167; figures 20 (flowering) & 21 (in habitat).

Turbinicarpus-schmiedickeanus-SS

Reported chemistry:

Phenethylamine (1.1% [± 0.12] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
Tyramine (5.46% [± 0.14] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
N-Methyltyramine (Trace detected)
Hordenine (43.02% [± 1.86] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
N-Methylmescaline (1.02% [± 0.21] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
N,N-Dimethylmescaline (Trace detected)
O-Methylanhalidine (2.76% [± 0.42] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
Anhalinine (17.19% [± 1.00] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
Anhalonidine (19.86% [± 1.41] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
Pellotine (9.02% [± 0.06] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
    Štarha et al. 1999

Turbinicarpus schmiedickeanus ssp. dickisoniae (Glass & Foster) N.P.Taylor

This species appears listed as containing Mescaline in Štarha 2001c but the only citation included was Štarha et al. 1999c. Which does NOT state that.

Turbinicarpus-dickisoniae-191

Turbinicarpus dickisoniae

Turbinicarpus schmiedickeanus (Bödeker) Buxbaum & Backeberg  subsp. flaviflorus  (Frank & Lau) Glass

Charles Glass (in R. Ortega-Varela & C. Glass) (1997) “Guia para la Identificacion de Cactaceas Amenazadas de Mexico” (Identification Guide to theThreatened Cacti of Mexico), as Turbinicarpus schmiedickeanus subsp. flaviflorus.
Gerhart Frank & A.B. Lau (1979) Kakteen und Andere Sukkulenten, 30 (1): 6, as Turbinicarpus flaviflorus.

Also published with a handful of other names that are not included here.

 

Reported to contain traces of mescaline.

Turbinicarpus-flaviflorus

Turbinicarpus flaviflorus

Etymology: In reference to the yellow flower.

Distribution & occurrence: Known only from Santa Rita, San Luís Potosí. Like many Turbinicarpus species it grows within a very limited area.

Turbinicarpus-flaviflorus-SS-01

Turbinicarpus flaviflorus

It forms globose to cylindrical greyish-green [Anderson] slate grey-green [Frank & Lau] stems that can reach 3 or 4 inches tall with age. (Club-shaped: 1.5 inches wide and 3.5 inches tall, Anderson)
Apex of plant is filled with white hair.
Spines are corky and twisting.
(Beet-like root [Frank & Lau])
Yellow flowers, 5/8th inch wide; in early summer.
Description adapted from Anderson 1998 and Sacred Succulents Seed supplement listing 1 except where indicated.

Turbinicarpus-flaviflorus-HBG-2006-P1010668

Turbinicarpus flaviflorus HBG

Photo with flower: Anderson 1998; page 114
See also Frank & Lau 1979 KuaS, 30(1): 6-7.

Miles Anderson describes it as rot prone and doing best when kept rootbound in a small pot.
He notes that it can handle 25°F for brief periods.

Turbinicarpus-flaviflorus-SS-02

Turbinicarpus flaviflorus (SS)

Reported chemistry:

Phenethylamine (1.01% [± 0.21] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
Tyramine (3.08% [± 0.08] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
N-Methyltyramine (Trace detected)
Hordenine (92.05% [± 0.71] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
Mescaline (Trace detected)
N-Methylmescaline (Trace detected)
O-Methylanhalidine (2.89% [± 0.46] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm fresh)
Anhalinine (Trace detected)
Anhalonidine (0.88% [± 0.12] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
Pellotine (0.15% [± 0.07] of total alkaloid fraction of 100-250 mg total alkaloids per 100 gm of fresh plant)
    Štarha et al. 1999

Turbinicarpus schmiedickeanus var. schwarzii  (Shurly) Glass & Foster [Plant name may be invalid?]

Ernest William Shurly (1948) Cactus and Succulent Journal of Great Britain, 10: 93, as Strombocactus schwarzii.
Charles Glass & Robert Foster (1977) Cactus & Succulent Journal (USA), 49: 161-177, as Turbinicarpus schmiedickeanus var. schwarzii.
ITIS gives the accepted name as Turbinicarpus schmiedickeanus ssp. schwarzii which is from Nigel P. Taylor (1998) Cactaceae Consensis Initiatives, 5: 14.
Zachar, Milan (2004) The Genus Turbinicarpus, instead absorbs it into Turbinicarpus schmiedickeanus subsp. macrochele var. macrochele in the back sections of synonyms yet in the text seems to equate Shurly’s wild populations with klinkerianus. What seems to be clear is that Zachar found problems existed with the original collection sites, and the details concerning the plants that were purportedly collected at that locale, so he rejected “schwarzii” as an invalid name.
Also appearing as:
Leo Kladiwa (in Hans Krainz) (1975) Kakteen, 61: CV 3b. (Toumeya macrochele var. schwarzii).
Alexander Borissovitch Doweld (2000) Sukkulenty, 3 (102): 70. (Turbinicarpus macrochele subsp. schwarzii).

 

Mescaline reported as trace amounts.

Turbinicarpus-schwarzii-UC

Turbinicarpus schwarzii (UC)

 

Etymology: Named after its discoverer Fritz Schwarz.

Distribution & occurrences: East of San Luís Potosí, Mexico (Backeberg 1977) San Luís Potosí. Encountered near junction of road from Charco Blanco to Guadalcazar, SLP. East of there, near Cerros Blancos, south of Mier y Noriega, Glass & Foster found a bluish green form with lavender or pale purple flowers. (Glass & Foster 1977). (See comments in Zachar.)

Habitat: Shurly 1941 commented that it occurs “in heavy black earth among small green plants or grass and mostly under shrubs”

Original description:
“Planta simplex; radix maxime evoluta. Corpus depresse semi-globosus, turbinatus; tubercula subapplanata, rhomboidea, quadrangula, latice aquoso, axillae nudae; spiris 5 et 8 spinae sive 1 sive 2 antica brevis, postica elongata, vertice plantae tantum evolutae; areolae ovatae, setis sericeis copioso-indutae, vertice plantae tantum evolutae. Flores albi, prope medium plantae verticem ex areolis proxime ante spinas exorientes.” p. 93, Shurley 1948.

Single small hemispherical (Backeberg 1977), turbinate with
flattened apex (Glass & Foster 1977), stems to 3.5 cm (Backeberg 1977), 4(-5) cm (Glass & Foster) in diameter. To 2 cm tall (Shurly).

The basal section can reach 3 cm long (Backeberg 1977).
Bears a thick taproot (Anderson 1998).
While normally solitary in the wild, they have been observed to form clumps up to 5 inches across in cultivation acording to Anderson 1998.
Tuberculate ribs are brownish to pale green and set in 5 and 8 spirals (Backeberg 1977). Pale green to bluish green to brownish green; flattened, somewhat 4-angled (Glass & Foster 1977).
Areoles are minutely tufted (Backeberg 1977).
1-2 whitish or yellowish brown [or horn-colored: Glass & Foster 1977] spines up to 2 cm in length. Spines later fall off (Backeberg 1977), “when 2, the lower is 4-20 mm long, the upper ca. 20 mm long, cardboard-like in texture” (Glass & Foster 1977).
Bell-shaped-rotate (Backeberg 1977), rotate-campanulate (Glass & Foster 1977), flower is white, suffused with green, and bears a reddish midstripe (Backeberg 1977), white to lavender or pale purple (Glass & Foster 1977). Flowers are 3 cm long and 4 cm in diameter (Backeberg 1977).
Stigma has 5-6 long, narrow, linear white lobes that are spreading & pubescent (Glass & Foster 1977).
Filaments are pale purple with orange-yellow anthers (Glass & Foster 1977.
Flowers several times during late spring and summer (Anderson 1998).
Fruit naked and dehiscent along a longitudinal split (Glass & Foster 1977).
Seeds small, black and rough verrucose (Glass & Foster 1977).

Description adapted from:
Backeberg 1977; page 501
Glass & Foster 1977

EM seed photo on page 170 of Glass & Foster 1977)
Photo on page 162; fig. 5 (seedling), page 164 fig. 12, and page 169; figures 29 (close-up), 30 (flowering in habitat), 31 (in habitat) & 32 (flowering)
Photo with flower: page 114 of Anderson 1998
(See also Shurly 1941 CSJGB 93)

Miles Anderson describes it as being rot prone.
He adds that it can handle 20°F for brief periods.
Shurly 1941 commented that “The plants need to be kept fairly dry.”

Reported chemistry:

Phenethylamine (1.07% [± 0.42] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
Tyramine (2.92% [± 0.25] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
N-Methyltyramine (Trace detected)
Hordenine (48.81% [± 2.72] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
Mescaline (1.26% [± 0.21] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
N-Methylmescaline (0.98% [± 0.24] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm fresh)
N,N-Dimethylmescaline (Trace detected)
O-Methylanhalidine (2.82% [± 0.41] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
Anhalinine (39.57% [± 1.14] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
Anhalonidine (0.52% [± 0.11] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
Pellotine (0.41% [± 0.11] of total alkaloid fraction of 250-500 mg total alkaloids per 100 gm of fresh plant)
  Štarha et al. 1999

Stenocereus

The members of Stenocereus have typically worn four or more names during their botanical history.

Stenocereus is derived from the Greek word stenos “slender”; for sake of having thinner branches than a true Cereus spp.; however, this is not true for all Stenocereus and Cereus species. “Cereus” came from the Latin cera meaning “waxy” in reference to the candle or candelabra-like shape of the Cereus species.
Lemaireocereus was named after Charles Lemaire.
Hertrichocereus after William Hertrich.
Rathbunia after Richard Rathbun.
Ritterocereus after Friedrich Ritter.

More detailed information concerning the published analysis of these species can be found in Sacred Cacti Part C, section 2: Cactus Chemistry By Species.

The species of interest in this discussion:

Stenocereus beneckei

Stenocereus eruca

Stenocereus hystrix (This will be discussed within Questions & Errors – an entry is due for completion in the near future.)

Stenocereus stellatus

Stenocereus treleasei

Stenocereus beneckei (Ehrenberg) Buxbaum

Carl Ehrenburg (1844) Botanische Zeitung, 2: 835, as Cereus beneckei.
Alvin Berger & Franz Buxbaum (1961) Botanische Studien, 12 (Entwickl. Trib. Pachycereae): 99, as Stenocereus beneckei.

Also appearing as:

Hertrichocereus beneckei in Backeberg (1951) Cact. Succ. J. (USA), 23: 120.
Lemaireocereus beneckei in Britton & Rose (1923) Cactaceae, 4: 273, fig. 247.
Rathbunia beneckei in P.V. Heath (1992) Calyx, 2 (3): 103.

Mescaline is present in trace amounts.

Stenocereus_beneckei_tipwithbuds_5_5widecolor

Stenocereus beneckei

Etymology: Specific name beneckei was named for the German consolate in Mexico, Stephan (Etienne) Benecke.

Distribution & occurence: Occurs in Mexico; in Guerrero in the Canyon de la Mano and del Zopilote. It may also occur in Puebla. Backeberg 1960

Occasional in occurrence between Coxcatlan (Puebla) and Teotitlan (Oaxaca): Jorge Meyrán García 1973.

Stenocereus-beneckei-LD

Stenocereus beneckei

“Stamm ästig, hellgrün, mit weissem Staube bedeckt, welcher sich abwischen lässt, 7–10 kantig, 1½ – 2½ Z. stark;
Furchen an den weniger kantigen stumpf; Kanten abgerundet, höckerig;
Höcker kegelförmig, stumpf, au der Spitze der Pflanzen eyrund oder rundlich, 6–9 L. lang, 1–1½ Zoll von einander entfernt;
Scheibe rund, mit kurzem, braunem oder schwarzem (abfärbendem?) Filz, später nackt;
Stacheln 1–9, unregelmässig, stark, steif, nagelförmig, ungleich, braun, schwarzbraun, an der Spitze schwarz, 1 Lin. – 2 Z. lang.” column 835 in Ehrenberg 1844.

Plant is bright green but may be reddened, around 1.5 meters tall, may be erect or prostrate with sprawling branches that have 7 to 9 ribs.

The areoles are set around 2.5 to 4 cm apart.

5 radial spines are around 1.5 cm long; one central spine up to 5 cm long. Sometimes the spines have fallen off.

Flowers are 7.5 cm long and 6 cm in diameter.

Red colored fruit is 5 cm long and 3 cm in diameter.

Backeberg 1960 4: 2235. (as Hertrichocereus pp. 2232-2235.) and García 1973.

Stenocereus-beneckei-HBG-2006-P1010615

Stenocereus beneckei

Photograph of entire plant p. 2233, fig. 2131.
Plant with flower page 2233, fig. 2132, plant with flower buds fig. 2133, page 2234 in Backeberg 1960 vol. 4.
Also see: Danny Schuster 1990; color photograph with side view of a flower on page 135.

Stenocereus-beneckei-HBG-2006-tip

Stenocereus beneckei

Reported analysis:

Mescaline was present at less than 0.01% (tlc and ms-ms)

3,4-Dimethoxyphenethylamine was indicated by tlc as less than 0.01% while ms-ms estimate was 0.01%.

3,5-Dimethoxy-4-hydroxyphenethylamine was estimated at 0.01% (tlc and ms-ms)

Ma et al. 1986

Stenocereus_beneckei_HBG_march2006_C_3widecolor

Stenocereus beneckei

Stenocereus eruca (Brandegee) Gibson & Horak

Townshend Stith Brandegee (1889) Proceedings of the California Academy of Sciences, ser. 2, 2: 163, t. 7, as Cereus eruca.
Arthur Charles Gibson & Karl E. Horak (1979) Annals of the Missouri Botanical Gardens, 65: 1007, as Stenocereus eruca.
Best known as Machaerocereus eruca, which was published in Nathaniel Lord Britton & Joseph Nelson Rose (1920) Cactaceae, 2: 115, fig. 171, 172.

Also appearing as:

Lemaireocereus eruca in N.L. Britton & J.N. Rose (1909) Contributions from the U.S. National Herbarium, 12: 425.
Rathbunia eruca in P.V. Heath (1992) Calyx, 2(3): 102.

Mescaline is present in trace amounts.

Stenocereus-eruca-HBG-2006-P1010380

Stenocereus eruca

Etymology: Machaerocereus was from macaera “dagger”, hence one common name ‘Dagger Cactus’, in reference to the shape of the spines; eruca is similarly from the Greek meaning “caterpillar” in reference to its creeping habit.
Pizzetti 1985

Stenocereus-eruca-bigger-454

It is easy to see why some people would call this the “dagger” cactus.

Common names: Most commonly called the “Creeping Devil.” Also known as “Chirola” and “Chirinole” and “Chilenola.”

Distribution & occurrence: From Mexico in the Baja, Llano de la Magdalena and Magdalena Island. Brandegee described it as being “Common on the sand of Magdalena Island and about San Jorge.”

 

Stenocereus-eruca-HBG-2006-P101163

Stenocereus eruca in Oz.

“Prostrate, very rarely branched, 13-ribbed, 3-4 feet long, 3-4 inches in diameter; rooting from the under side of the older growth, decaying at one end and growing forward at the other, generally in patches of 20-30, probably originating from a common center: areolae 4-6 mm. in diameter, separated about the same distance: spines about 20, stout, ash-colored, less than an inch long, the exterior cylindrical, the interior stouter, angular, somewhat and the lower central one much flattened, more than an inch long, angular, strongly reflexed: flowers and fruit not seen. […] The manner of growth, with uplifted heads and prominent reflexed spines, gives the plants a resemblance to huge caterpillars. The flowers are said to be yellow.” p. 163 in Brandegee 1889.

Plants grow prostrate with the growing tip slightly elevated. Many times the decaying base of the plant with new roots forming under the plant give the impression that they are slowly crawling away from their point of origin leaving a trail of debris (hence its most common name).

Stems are usually 1 to 3 meters in length and 4 to 8 cm in diameter.

There are usually around 12 ribs with large areoles set about 2 cm apart.

They are fiercely spined (unequal and pale grey or white) with around 20 spines per areole.

Yellow flowers [cream colored; sometimes with pink base] are 10 to 14 cm [4-5 in.] long and 4-6 cm wide; forming a 4 cm long, spiny, scarlet fruit. Spines fall off when ripe.

Backeberg 1960 4: 2114-2115, pictures pages 2114, fig. 1996 and 2115, fig. 1997, and Britton & Rose 1920 2: 115-116, pictures, fig. 171 on page 115 (in habitat) and fig. 172, page 116. and Pizzetti 1985: entry #156 (has photo of young plant).

Stenocereus-eruca-sideviewclose

Stenocereus eruca

Reported analysis:

Mescaline was indicated to be present at less than 0.01% (dry weight) by tlc but was not observed using tandem mass spectrometry.

3,4-Dimethoxyphenethylamine was indicated to be present at less than 0.01% (dry weight) by tlc but was not observed using tandem mass spectrometry.

3,5-Dimethoxy-4-hydroxyphenethylamine was indicated to be present at 0.01% (dry weight) by tlc but was not observed using tandem mass spectrometry.

Ma et al. 1986

The triterpenes, Lupeol and Lupenone, were isolated by Kinoshita et al. 1992.

Djerassi et al. 1953a had earlier identified Queretaroic acid and Oleanolic acid.

Djerassi et al. 1955 found a triterpene composition quite similar to that of both Lemaireocereus stellatus and Lemaireocereus treleasei. They detected no alkaloids. (See comments on Djerassi’s analysis farther below)

W. Taylor Marshall & Thor Methron Bock 1977 noted that this cactus, although popular, is very prone to rotting and rarely flowers in cultivation. They recommend that the soil be well draining but not too rich and that due to its slowness in rooting, water should be withheld at first and then given only lightly.

Stenocereus-eruca-tip

Stenocereus eruca cultivated in California

Stenocereus hystrix

See the entry under Questions & Errors

Stenocereus stellatus (Pfeiffer) Riccobono

Louis Karl Georg Pfeiffer (1836) Allgemeine Gartenzeitung, 4: 258, as Cereus stellatus.
Vincenzo Riccobono (1909) Bollettino delle R[eale] Orto Botanico di Palermo, 8: 253, as Stenocereus stellatus.

Also making an appearance as:
Lemaireocereus stellatus in Britton & Rose (1909) Contributions from the U.S. National Herbarium, 12: 426, pl. 69.
Neolemaireocereus stellatus in Backeberg (1942) Jahrbuch der Deutschen Kakteen-Gesellschaft in der Deutschen Gesellschaft für Gartenkultur, 1941, pt. 2: 46.

Mescaline is present in trace amounts.

Stenocereus-stellatus-tip-buds

Stenocereus stellatus

Water content: 87.4% water by weight.

Common names: “Pitayo” and “Xoconostle” García 1973

Fruit is called “Joconoxtle” Helia Bravo 1931. Britton & Rose 1920 also noted the fruit to be known by that same name in local markets and occasionally as “tuna”.

Etymology: “stellatus” is in reference to the starry or “stellar” appearance of the spine clusters. The adults can be stunning.

Stenocereus-stellatus-column

Stenocereus stellatus

Occurrence & distribution: Puebla, Oaxaca and Tehuantepec in Mexico. Backeberg 1977

Southern Puebla & Northern Oaxaca. García 1973

Pfeiffer 1836

Pfeiffer 1836

Stenocereus-stellatus-column

Stenocereus stellatus

Erect columns to 3 meters tall. Matte, dark green often reddish (Backeberg). [Pale bluish green (Britton & Rose).] Branching mainly from the base. Branches can be up to 8 cm in diameter.

The 8 to 12 ribs may show tubercles but are low and obtuse.

The areoles are white, set 1 to 2 cm apart and have 8 to 12 spreading radial spines up to 12 mm long. The 10 to 12 radial spines usually are shorter than the centrals. There are 1 to 3 brown central spines which can reach 2 cm. (Britton & Rose say they can reach 5 to 6 cm)

It bears white flowers at or near the apex, which are pink on the outside (red according to Britton & Rose) and up to 6 cm long (4 in Britton & Rose) The deciduously spiny spherical fruit is 3 cm in diameter, red and edible.

Backeberg 1977: 463 and

Britton & Rose 1920 2: 92-93.

 

Stenocereus-stellatus-oldertip

Stenocereus stellatus

See also Backeberg 1960 4: 2223, pictures on page 2220, fig. 2116 and on 2221, fig. 2117. Also fig. 17 in García 1973 and fig. 136, page 94 in Britton & Rose for a picture in habitat. Also see Bravo 1931: page 123, fig. 8 for a picture of a plant with fruit.

Edible but slightly acid fruit. García 1973

 

Stenocereus-stellatus-youngtip

Stenocereus stellatus

Reported analysis:

Mescaline 0.01% by dry weight (tlc, ms-ms)

3,4-Dimethoxyphenethylamine and
3,5-Dimethoxy-4-hydroxy-phenethylamine present in similar amounts.
Ma et al. 1986

Djerassi et al. 1955 found 3.5% triterpenes (reporting both oleanic acid and the triterpene lactone stellatogenin) but reported no alkaloids from this species. See comments on Djerassi under Stenocereus eruca.

Stenocereus-stellatus-column-detail

Stenocereus stellatus

    

Stenocereus treleasei (Rose) Backeberg

Joseph Nelson Rose (1909) Contributions from the U.S. National Herbarium, 12: 426, tab. 70 as Lemaireocereus treleasei.
Curt Backeberg (1951) Cactus & Succulent Journal (USA), 23: 120, as Stenocereus treleasei.

Also appearing as:
Cereus treleasei in Vaupel (1913) Monatsschrifte fuer Kakteenkunde, 23: 37, 58.

Mescaline is present in trace amounts.

Stenocereus-treleasi-oldertip

Stenocereus treleasei

Water content: 82.6% water by weight.

Common name:Tunillo” Djerassi et al. 1956; also Bravo 1931.

Etymology:treleasei” was for the botanist William Trelease.

Distribution & occurrence: Oaxaca, Mexico (Road between Mitla and Oaxaca).

Stenocereus-treleasi-youngertip

Stenocereus treleasei

Usually simple columns to 7 meters tall. Rarely branching from the flank.

There are up to 20 tubercled ribs with a v-shaped depression.

Spines are short and yellowish, borne in groups of 7 to 9. Later one grows longer and appears more distinctly central.

Diurnal flowers resemble S. stellatus but are up to 5 cm. in length.

Fruit is red and covered with deciduous spines.

Backeberg 1977: page 463 and

Britton & Rose 1920 2: 93-94.

Stenocereus-treleasi-tips

Stenocereus treleasei

Britton & Rose noted that the plant is not common in the deserts around Oaxaca but does occur in clumps. They mention that while its flowers and fruit resemble those of Lemaireocereus stellatus it has a different habit, more ribs and different areoles. They characterize it by having seldom branching, strict, elongated stems.

See also Backeberg 1960 4: 2223, picture on page 2222, fig. 2120.
Britton & Rose include a picture in habitat on page 95, fig. 137;
as does Bravo 1931: page 122, fig. 7

Stenocereus-treleasii-HBG-2006-C

Stenocereus treleasei

Reported analysis:

Mescaline 0.01% by dry weight (tlc, ms-ms)

Also found 3,4-Dimethoxyphenethylamine and
3,5-Dimethoxy-4-hydroxyphenethylamine present in similar
amounts.

Ma et al. 1986

Ma’s specimen was unvouchered and may actually have been a form of S. stellatus.

Djerassi et al. 1956 found oleanic acid and the triterpene lactone stellatogenin but reported that no alkaloids were present. See comment on Djerassi  below.

Stenocereus-treleasii-tip

Stenocereus treleasei

re: Djerassi reporting the detection of no alkaloid

During their studies elucidating the terpenoids present in a number of plants, Carl Djerassi and coworkers published a series of papers in which they reported finding no alkaloids in numerous species that were later determined by other workers to contain alkaloids.

Djerassi’s alkaloid detection procedure usually consisted of extracting with alcohol, evaporating to a residue and extracting the residue with ether. They assumed any alkaloid present would be extracted into the ether and show alkaline results. Many alkaloids, including mescaline, are not particularly soluble in ether. Others are neutral rather than alkaline. If one examines their results, it rapidly becomes unsurprisingly apparent what the few alkaloids they did report from cacti were all ether soluble (such as anhalonidine reported from Lemaireocereus (Pachycereus) weberi in Djerassi et al. 1954).

Many cacti which they assayed as negative (such as several of the numerous Lemaireocereus spp. they looked at) were subsequently shown to contain only trace amounts of alkaloids by later workers but others (such as Trichocereus peruvianus) proved to be a good source of alkaloids.

Djerassi and coworker’s papers should be noted by chemotaxonomists.
Both alkaloids and compounds such as triterpenes and lactones are valuable qualitative marker compounds for chemotaxonomic work in spite of their quantitative variability.
Unusual amino acids observed in seeds and flavones are good and proven markers.
Biominerals also appear to have diagnostic usefulness.

Chemotaxonomy is best viewed as a supplemental tool and cannot replace the existing taxonomic system on its own. While alkaloid and triterpenes present reflect what enzymes are expressed and hence mirror elements of genetic structure, not all genes are necessarily expressed. This is an important point in understanding the sometimes conflicting array of plant products formed by closely related plants.

Anyone with an interest in chemotaxonomic approaches is urged to obtain a current and solid understanding of and familiarity with what is presently known in immunology concerning variability of gene expression, (regardless of their qualifications and background). What has been elucidated concerning the origin of the variability and diversity of antigen receptor sites (in humans) is most applicable towards enlightenment in this area. Chemotaxonomy might be welcomed and understood rather than resisted and belittled for its limitations.